Small gene regulatory circuits can encode a surprising diversity of dynamical behaviors. A biophysical model of the AC-DC motif reveals over thirty distinct bifurcation structures and shows how molecu...

Applying dynamical systems theory to single-cell data can provide a detailed picture of the cellular states observed during cell fate decisions. This study presents a dynamic landscape analysis (DLA) ...

Small gene regulatory networks (GRNs) are well-established biological modules that underpin cellular decisions and dynamical function. Their theoretic…

Like choreography, development consists of a highly ordered suite of steps and transitions. Modifying developmental tempo can affect final size and composition of tissues, as well as their plasticity…

Evolutionary Biology and Ecology of Cancer

The behavior of nonlinear systems near critical transitions has significant implications for stability, transients, and resilience in complex systems. Transient times, $\ensuremath{\tau}$, become extr...

The behavior of nonlinear systems near critical transitions has significant implications for stability, transients, and resilience in complex systems. Transient times, $\ensuremath{\tau}$, become extr...