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Inés

@ines-ddo.bsky.social
151 followers 126 following 3 posts

Postdoc at the Dunn School (University of Oxford) researching how Salmonella evades the Immune system

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Inés @ines-ddo.bsky.social · 11/05/2026
Our paper is finally out! 🥳 If you want to know how a single Salmonella effector rewires the whole macrophage transcriptional landscape by hijacking one host transcription factor, check our latest research! Thanks to the @thurstonlab.bsky.social and @peterwshill.bsky.social labs for an amazing work!
sciencedirect.com
Salmonella effector SteE reprograms the macrophage regulatory network to drive specific hyperactivation of STAT3 target genes
The ability of Salmonella Typhimurium to exploit macrophages as a niche for survival, replication, and dissemination is central to its pathogenesis. T…
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The Dunn School, Oxford @dunnschool.bsky.social · 13/09/2025
We had a fantastic time today showcasing our amazing history and cutting-edge research at #OxfordOpenDoors! Visitors learnt about 100 years of medical research, the development of penicillin and our ongoing work on microbiology and AMR. Thanks to all the volunteers!
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Inés @ines-ddo.bsky.social · 13/09/2025
Great time showcasing the amazing science we do at the @dunnschool.bsky.social at #OxfordOpenDoors today!
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Teresa Thurston @thurstonlab.bsky.social · 16/07/2025
We have a new preprint on Salmonella effector SteE! Here we describe how kinase reprogramming drives transcriptional remodelling of the infected macrophage www.biorxiv.org/cgi/content/... - work led by @ines-ddo.bsky.social and fantastic collaboration with @peterwshill.bsky.social
biorxiv.org
Salmonella Effector SteE Reprogrammes the Macrophage Regulatory Network to Drive Specific Hyperactivation of STAT3 Target Genes
The ability of Salmonella Typhimurium to exploit macrophages as a niche for survival, replication and dissemination is central to its pathogenesis. The effector SteE, which polarises macrophages into ...
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Inés @ines-ddo.bsky.social · 03/07/2025
It’s been a pleasure to attend and present my research at #ETOX2025! It’s amazing to see all the exciting science happening in the field!
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Teresa Thurston @thurstonlab.bsky.social · 18/03/2025
We recently had a day of Salmonella-focused fun. Special thanks to @eadirectordndi.bsky.social and PhD student Kelvin Kerring for joining us from Kenya to discuss iNTS. All made possible via the Global hubs fund and @embo.org YIP networking fund. @jayhinton.bsky.social @katrinrittinger.bsky.social
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Teresa Thurston @thurstonlab.bsky.social · 13/05/2025
How can a Salmonella effector change the specificity of a host kinase? SteE mediates kinase reprogramming via mimicry of conserved eukaryotic-like motifs- doi.org/10.1038/s443... Great collaboration with @katrinrittinger.bsky.social + big thanks to all authors & congrats to lead PDRA Ioanna Panagi!
embopress.org
Bacterial effectors mediate kinase reprogramming through mimicry of conserved eukaryotic motifs | EMBO reports
imageimageA virulence protein from diverse bacteria switches the amino acid specificity of the eukaryotic kinase GSK3. This kinase reprogramming depends on several short linear motifs that each appear...
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Timesh Pillay @timeshpillay.bsky.social · 04/03/2025
During my PhD at @crick.ac.uk and @imperialcollegeldn.bsky.social, I explored the molecular interaction between host and pathogen. My question: How have pathogenic bacteria evolved to manipulate their host environment during infection? 🦠https://biorxiv.org/content/10.1101/2025.03.01.640964v1 1/11
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