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Reposted by neurosock

neurosock @neurosock.bsky.social · 01/10/2026

Mix. selectivity is everywhere in cortex: from vis. to PFC This paper relates to Cover's theorem but the typical explainer kind of sucks I'll try to explain how the theory relates to the paper, and the importance of "weird" neurons A🧵with my toy model and notes: #neuroskyence #compneuro #NeuroAI

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neurosock @neurosock.bsky.social · 01/10/2026

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neurosock @neurosock.bsky.social · 04/08/2026

All-or-nothing behaviors aren't personal failures; they're circuit disruptions. Along the midline of the frontal lobe, the prelimbic cortex (PL) integrates memory engrams from the hippocampus with threat signals from subcortical networks ... #Neuroscience #BrainResearch #PTSD #Psychology

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neurosock @neurosock.bsky.social · 16/07/2026

This recent post by @earlkmiller.bsky.social got my attention. It shows how abstraction could emerge in the primate PFC. The paper is hard, but the main idea can be simplified to low-dims, so I made fun a little animation. A🧵with my toy model and notes: #neuroskyence #compneuro #NeuroAI

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neurosock @neurosock.bsky.social · 25/06/2026

🚨new paper explainer🚨 Took me six months to prepare but here it is ... The view that prefrontal is the boss is now outdated. This nice review shows how BG, dlPFC, pMD and M1 work in tandem to come to a decision. A🧵with my toy model and notes: #neuroskyence #compneuro #NeuroAI

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neurosock @neurosock.bsky.social · 21/05/2026

I really love when real science stories are presented in a fun format. Check this one out. Got me immediately hooked and motivated me enough to go back to writing. Reminds you also that papers is about finding the truth, and not about "writing a paper". comics.phillyharper.com/

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neurosock @neurosock.bsky.social · 20/04/2026

Raw thought: In the not so distant future there will be company the size of today's Apple **solely** dedicated to build a **single** detailed robot hand for humanoids and prostheses. It is such a hard problem ...

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neurosock @neurosock.bsky.social · 18/12/2025

Every year, I put together a year's review of what's going on in the crazily evolving world of brain chips, #Neuralink and #BCI's. 2025 was huge for BCIs, but we saw many other trends. Here are my top-10 trends of the year and what to watch for in 2026: #neuroskyence #NeuroAI #NeuroTech

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neurosock @neurosock.bsky.social · 18/12/2025

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neurosock @neurosock.bsky.social · 11/12/2025

The new Titans architecture shows how badly Google wants to go back to recurrence. Why? Recurrence is damn cheap. This paper shows how the brain does it. Striatum, cortex, HPC, BG, and thalamus, in recurrent loops with shortcuts. A🧵with my toy model and notes: #neuroskyence #compneuro #NeuroAI

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neurosock @neurosock.bsky.social · 11/12/2025

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neurosock @neurosock.bsky.social · 28/11/2025

The hippocampus is not a library, it is a simulation engine. HPC is known for storing maps of the environment but not so known for generating planned trajectories. This paper proposes that recurrence in CA3 is crucial for planning. A🧵with my toy model and notes: #neuroskyence #compneuro #NeuroAI

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neurosock @neurosock.bsky.social · 27/11/2025

Finishing a new paper notes post. Should be ready in a few hours. Here a little preview 🚀.

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neurosock @neurosock.bsky.social · 13/11/2025

Decisions under uncertainty are a coordinated action of PFC, pre/motor, BG, and thalamus. This model tries to explain decision impairments by hyperactive D2 receptors We can clarify the paper by building a mouse with schizophrenia. A🧵with my toy model and notes: #neuroskyence #compneuro #NeuroAI

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neurosock @neurosock.bsky.social · 30/10/2025

Dopamine ≠ reward but turns out, also not the learning molecule we thought. If DA RPE is the emperor, this work SCREAMS it was running naked all the time. This paper got quite some attention recently. Let's simplify it a bit. A🧵with my toy model and notes: #neuroskyence #compneuro #NeuroAI

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neurosock @neurosock.bsky.social · 25/10/2025

New habits move from the Prefrontal Cortex (conscious effort) to the Basal Ganglia (habit loop). A trick is to automate the first 30 seconds of a habit, minimizing the PFC's required 'energy' for initiation until the Basal Ganglia takes over. #LifeHacks #SelfImprovement #Brain

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Reposted by neurosock

neurosock @neurosock.bsky.social · 22/10/2025

To plan the future, the PFC represents a step-by-step map of actions, and at every step, this plan moves to the past like a conveyor belt. This proposes a simple subspace architecture for planning. A toy environment can clarify it. A🧵with my toy model and notes: #neuroskyence #compneuro #NeuroAI

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neurosock @neurosock.bsky.social · 22/10/2025

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neurosock @neurosock.bsky.social · 18/10/2025

To stop unwanted thoughts, the PFC sends a control signal to the hippocampus (brain's memory retrieval center). This activates local inhibitory interneurons (GABA), which then suppresses retrieval. Difficulties in this pathway may underlie #PTSD, #OCD, anxiety, and #depression.

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neurosock @neurosock.bsky.social · 15/10/2025

Impressive (200+ bps) BCI decoding speeds by Paradromics reported this month. Plus BCIs updates from: - E11 Bio - Morgan Stanley - Neuralink - New England Journal of Medicine - Precision - Figure - Stanford, China and more. Here's everything you need to know and my opinions:

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neurosock @neurosock.bsky.social · 09/10/2025

A core function of cortex is predicting what happens next given the world's state. This recent paper from Oxford shows how cortical layers may use a delay trick to learn to predict. A simple illustration can explain the idea. A🧵with my toy model and notes: #neuroskyence #compneuro #NeuroAI

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neurosock @neurosock.bsky.social · 08/10/2025

A core function of cortex is predicting what happens next given the world's state. This great recent paper from Oxford shows how cortical layers may use a clever delay trick to learn to predict. A simple illustration can explain the main idea. Here is my toy model and notes:

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Reposted by neurosock

neurosock @neurosock.bsky.social · 02/10/2025

The mammalian cortex acts as tutor, keeping the job of striatum simple. This totally changes our knowledge of how RL works in the brain. Instead of a new paper, I will dig in what could be the mysterious new mechanism of my last post. Let's deep dive into theories of cortex:

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neurosock @neurosock.bsky.social · 02/10/2025

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neurosock @neurosock.bsky.social · 25/09/2025

Dopamine (DA) in the dorsolat. striatum (DLS) is a teaching signal that shapes learning. DA in DLS ≠ RPE but = to stimulus-choice associations relevant to a learning strategy. This can be beautifully explained as saddles in a loss landscape. Here is my toy model and notes:

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neurosock @neurosock.bsky.social · 18/09/2025

This paper may solve a core neuroscience question of the last decades: What is the cortical code? Cognitive cortex also uses tuning, and latent variable span a non-linear manifold. Unlocking this work requires understanding why PSTHs are bad. Here is my toy model and notes:

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Reposted by neurosock

neurosock @neurosock.bsky.social · 10/09/2025

Significant progress in Brain Chips this month: I summarized everything from Paradromics, MIT Technology Review, UCL, Nature, Alterego, Meta, Neuralink, World Economic Forum, Duke University and more. Here's everything you need to know and my opinions:

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neurosock @neurosock.bsky.social · 18/09/2025

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neurosock @neurosock.bsky.social · 16/09/2025

I saw this recently as Fig. 1 of an AI paper that got quite some attention on X. Green-washing is a form of advertising that deceptively uses green PR to persuade the public that an organization's product is environmentally friendly. Can we call this Brain-washing? 🤦🏾‍♀️

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neurosock @neurosock.bsky.social · 10/09/2025

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neurosock @neurosock.bsky.social · 05/09/2025

Researchers were able to freeze learning in mice. This great recent work shows the striatum is required for skill learning but not skill use (through optogenetics). Understanding the memory-making mechanism helps understand the core idea. Here is my toy model and notes:

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neurosock @neurosock.bsky.social · 05/09/2025

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neurosock @neurosock.bsky.social · 31/08/2025

For my next paper summary I'd like to read something beyond neo cortex. ❤️⭐ I digged out the following 4 papers from my "to read" list. I am tending to pick #4. Any one you prefer? 🤔

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neurosock @neurosock.bsky.social · 28/08/2025

Most reports about this paper focused on the mind "password" aspect. But IMHO, the most exciting part is the existence of a neural intention axis. This is a slap in the face for modern motor neuro, worth simplifying for better understanding. Here are my notes and toy model:

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neurosock @neurosock.bsky.social · 27/08/2025

What a week last week: 🤓 NatComms paper corrections resubmitted. 🎉 Reached >17K people for the first time with something I love: making papers easy to understand. 👨🏽‍⚕️Dr confirms worrying issue was nothing to worry. 💸 ETH hits all time high. But I need to tell you this:

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neurosock @neurosock.bsky.social · 23/08/2025

Reactions of people hearing for the first time with a hearing aid. I can hardly hold back my tears, especially with the last one. I watch this video every once in a while to remind myself that working on brain chips is hard but worth it 🥲

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neurosock @neurosock.bsky.social · 21/08/2025

The brain uses orthogonal sub-dimensions in neural space as communication channels. This is a great new paper using Neuropixels from ~6500 neurons on 8 cortical and deep regions in mice. Simplifying the space helps a lot to understand the idea. Here is my toy model and notes:

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neurosock @neurosock.bsky.social · 20/08/2025

Brain interfacing technologies now use artificial direct, electrode communications. However, maximum bandwidth won't be achieved this way, but by thick, new bundles of biological neurons. Those are already being studied as biomaterial scaffolds for the recovery of spine injury.

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neurosock @neurosock.bsky.social · 16/08/2025

Brain Chip History 2012: Using a brain chip, brain researchers at Pittsburgh University allowed a woman to feed herself chocolate for the first time after many years of paralysis.

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neurosock @neurosock.bsky.social · 15/08/2025

Significant progress in Brain Chips this month: I summarized everything from Pittsburgh, Dartmouth, Sam Altman, Chicago, Figure, Germany, UCL, Princeton, Nature and more. Here's everything you need to know and my opinions:

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neurosock @neurosock.bsky.social · 12/08/2025

There was this discussion recently about wether the information throughput of the human brain was about 10 bits/s. Then you see this 🤣

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neurosock @neurosock.bsky.social · 07/08/2025

Gamers have .gg 2010's start-ups had .io AI companies have .ai I've an idea: What if we make .RO the official TLD for FROs, research labs, #DeSci, and in general research oriented organizations? There are plenty good reasons to consider this, here's my thinking 🧵:

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neurosock @neurosock.bsky.social · 22/07/2025

Three graphs showing neuro-technologies are accelerating. neuro/acc

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neurosock @neurosock.bsky.social · 15/07/2025

Researchers in Japan developed a light controlled Cockroach Cyborg. They use a UV light helmet to steer cockroaches by taking advantage of their tendency to avoid bright light. In a maze-like environment, 94% successfully escaped, compared to 24% of normal cockroaches. 🔗👇🏽

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neurosock @neurosock.bsky.social · 03/07/2025

This is a nice follow up to my previous rant re-post against people disregarding the Utah brain chip. There is a lot of knowledge on all those user/years. Spike life for 14 participants over 20y by @WillettNeuro & Co. Related links & preprint below 💬👇🏽

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neurosock @neurosock.bsky.social · 02/07/2025

Fleuron is a really interesting material for brain chips. It is super flexible and has a low body rejection. It can be used to cover electrodes and its transparent, so it could be used for optics. They just showed it can grow with tadpoles while reading their neurons. Link 👇🏾

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neurosock @neurosock.bsky.social · 27/06/2025

Writing an answer letter to reviewer and rewriting a paper. I am not using AI yet I have to constantly check my language hoping it doesn't sound like AI. In what world do we live in now ... 👩🏽‍💻

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neurosock @neurosock.bsky.social · 26/06/2025

Significant progress in Brain Chips this month: I summarized everything from Neuralink, UCDavis, Figure, Sanmai, China, Canada, Precision, Europe, Nature Neuroscience and more. Here's everything you need to know and my opinions:

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