Evan DeTurk @evandeturk.bsky.social · 08/10/2026Another unreal find, this time in the wild (aka a bookstore in Brooklyn)! Krimsky was an SftP member and wrote the first history of the controversy. I don't agree with all his takes but this book opted for detail at a time (1982) when biotech was getting hyped through the roof. 020
Evan DeTurk @evandeturk.bsky.social · 25/09/2026This is basically what happens after Asilomar with the gradual dismantling of NIH guidelines est by the conference. So yes, avoiding capture requires ongoing diligence. Unfortunately for the case of AI, governance is highly reactive rn and imo we can’t just start over without the companies. 100
Evan DeTurk @evandeturk.bsky.social · 24/09/2026IMO it was good that Asilomar started the convo, even if it was partially to avoid regulation and made science policy more reactive. Today, the AI slowdown provides a similar starting point. But we need non-tech CEOs to shape it too - that's how we avoid regulatory capture! 101
Evan DeTurk @evandeturk.bsky.social · 24/09/2026Luis makes this point @ the article's end: “What mattered at Asilomar was the lawyers who said: You need to be thinking about these larger consequences, and you are not the only ones to make this decision...It's not just...let the experts decide” 100
Evan DeTurk @evandeturk.bsky.social · 24/09/2026A useful article about Asilomar and how it applies to AI governance! I'd emphasize that what's needed is broad participation and not scientific self-regulation. Asilomar's success socially was that it provoked public engagement. www.nytimes.com/2026/09/23/u...nytimes.comHow Scientists Contained a Threat That Could Have Destroyed HumanityA half-century ago, scientists and lawyers agreed to strict self-regulation in DNA research to avoid catastrophe. Can A.I. follow the same model? 110
Reposted by Evan DeTurkAlondra Nelson @alondra.bsky.social · 23/09/2026Honored to be invited by Gov. Newsom to serve on the advisory committee supporting CA's AI safety and security initiative. We need durable institutional mechanisms like truly independent verification, auditing and mandatory reporting and the state is leading the way. www.gov.ca.gov/2026/09/23/g...gov.ca.govGovernor Newsom announces world-leading experts to deliver on his AI executive order, including advancing creation of a “kill switch” | Governor of California 46912
Reposted by Evan DeTurkDoudna Lab @doudna-lab.bsky.social · 19/09/2026Out now in Science: Two papers from our lab reveal VIPR, an RNA-guided DNA-targeting system in bacteriophages, providing clues to the origins of CRISPR www.science.org/doi/10.1126/... www.science.org/doi/10.1126/... Congrats to Peter Yoon, @kenjmloi.bsky.social @terryzzy.bsky.social, T.Docter & teamscience.orgA noncontiguous code for RNA-guided DNA recognition at the origin of CRISPR-CasCRISPR-Cas provides RNA-mediated adaptive immunity, but how its first RNA-guided effector arose is unclear. In this study, we report the discovery of Viral Interference Programmable Repeat (VIPR) syst... 217771
Evan DeTurk @evandeturk.bsky.social · 18/09/2026Was considering using some very expensive grey market philosophy tools. Thankfully Harry Collins intervened: 000
Reposted by Evan DeTurkCarl Zimmer @carlzimmer.com · 17/09/2026I wrote about what came before CRISPR 4 billion years ago: a war among viruses. Gift link: nyti.ms/3TBq4q0nyti.msThe Next Gene-Editing Technology May Also Be the Oldest (Gift Article)Scientists have discovered a powerful gene-targeting system in viruses. Billions of years old, VIPR seems to predate CRISPR and may be even more powerful. 114351
Evan DeTurk @evandeturk.bsky.social · 15/09/2026On today’s episode of “nerdy history of science eBay finds”…a vintage (I think?) button from antiwar/Marxist group Science for the People. Key group opposing recombinant DNA/genetic engineering research in the ‘70s. 020
Evan DeTurk @evandeturk.bsky.social · 20/08/2026Finally managed to get my hands on a physical copy of this! Great to see in our paper literally in print 081
Evan DeTurk @evandeturk.bsky.social · 07/08/2026The viruses in this paper infect bacteria rather than humans so responses like this are premature. Still, there is much to be done to avoid harmful hijacking of bio models like Evo! See: www.science.org/doi/10.1126/...science.orgAI-designed viral genomesThe generation of functional viral genomes has urgent biosafety and biosecurity implications 000
Reposted by Evan DeTurkZehan Zhou @zehanzhou.bsky.social · 05/08/2026We are PUBLISHED!!! Our mechanistic work on how CRISPR-Cas ancestors unwind DNA and how this can be used to engineer hypercompact plant editors can now be found on Mol Cell- if you are interested in what defines a good genome editor, this read is for you 😎 🔗 www.sciencedirect.com/science/arti...sciencedirect.com 12012
Reposted by Evan DeTurkBel Esain @isabelesain.bsky.social · 17/07/2026So excited to see our paper out in Science! Beyond grateful to my co-leads @petrskopintsev.bsky.social @evandeturk.bsky.social, all co-authors & collaborators, everyone in Doudna lab, and @innovativegenomics.bsky.social Being EsAIn in the DouDNA lab, it couldn't have been any other way ✨ 0103
Reposted by Evan DeTurkPetr Skopintsev @petrskopintsev.bsky.social · 17/07/2026Proud to present our work, published today in @science.org! My deepest gratitude to @isabelesain.bsky.social, @evandeturk.bsky.social, Jennifer and our collaborators in the Doudna, Cate, Banfield, and Jacobsen labs, and the @innovativegenomics.bsky.social! I hope you enjoy reading it! ✨ 04310
Reposted by Evan DeTurkInnovative Genomics Institute @innovativegenomics.bsky.social · 16/07/2026Out today in @science.org, Doudna lab researchers describe an #AI-assisted method for designing enhanced genome editors, testing close to 2000 in lab. Read more: innovativegenomics.org/news/ai-desi...innovativegenomics.orgAI-Assisted Technique Allows Scientists to Design New, Functional Genome Editors Beyond What Can Be Found in NatureAI-Assisted Technique Allows Scientists to Design New, Functional Genome Editors Beyond What Can Be Found in Nature - Innovative Genomics Institute (IGI) 1135
Evan DeTurk @evandeturk.bsky.social · 16/07/2026It's out! Check out the D-LabSky thread below 👇 Pleasure working with and learning from @petrskopintsev.bsky.social @isabelesain.bsky.social and the whole team on this oen 021
Evan DeTurk @evandeturk.bsky.social · 26/05/2026I wrote about the ethics of the Enhanced Games for my first Substack post more than 2 years ago. Last weekend, the event actually took place. If there's anything I think we should understand, it's the individualistic biomedical techno-optimism that the Games is pushing: substack.com/home/post/p-...substack.comThe reality of the Enhanced GamesSteroids won’t automatically make you a better person 000
Evan DeTurk @evandeturk.bsky.social · 21/05/2026William Heath’s 1828 “Monster Soup” of microbes. I particularly love the crustacean-looking guys on the right! Fascinating convergence of the histories of biology and the city - would love to get urban studies people's thoughts on this. 000
Evan DeTurk @evandeturk.bsky.social · 19/04/2026Edinburgh via history/philosophy of science eyes! Safe to say the National Museum of Scotland has reached their target audience with the Dolly the Sheep pen. And the largest of shoutouts to @neurathic.bsky.social for spotting the Huxley book for me. 042
Evan DeTurk @evandeturk.bsky.social · 13/04/2026Been reading through lots of old Bulletin of the Atomic Scientists magazines recently for an ongoing project. Here are some of the coolest biology-related covers and illustrations I’ve found: 001
Evan DeTurk @evandeturk.bsky.social · 29/03/2026Ever been even mildly conflicted about the potential of genetic engineering? Unsure what to make of the mix of cool science, therapeutic utility, and potential eugenic misuse? Wrote down a few thoughts on how the history of biology can help us manage some of these ethical issues 👇substack.comWe’re not the first generation to think about designer babiesThe past offers both hope and warnings 020
Evan DeTurk @evandeturk.bsky.social · 28/02/2026Thanks Jeremy! Sadly I had to leave out the Ithaca institute and many others since going for completion on Weill's philanthropy would have been tough. I mentioned the med school since it's probably the most visible of all his donations and UCSF since there was a direct parallel to be made. 010
Evan DeTurk @evandeturk.bsky.social · 28/02/2026Yes, you're absolutely right. Thanks for catching that, really not sure how that got in there... 000
Reposted by Evan DeTurkTim O’Brien @timobrien.bsky.social · 28/02/2026“If ever history demanded that Congress reclaim its constitutional monopoly in declaring war, that moment is now.” www.bloomberg.com/opinion/arti...bloomberg.comIran Strikes Feel Like 2003 All Over AgainLess than a year ago, US President Donald Trump gave a speech in the Middle East in which he excoriated his predecessors for their habit of launching “forever wars” in that region. Alluding to the Ame... 2429876
Evan DeTurk @evandeturk.bsky.social · 28/02/2026Asking questions like “who the heck is Stanley Hall named for?” can teach you a surprising amount!substack.comA walk through biology history at UC BerkeleyWhat building names can teach us about the history of science 341
Evan DeTurk @evandeturk.bsky.social · 26/02/2026Wrote about the clever ways people have figured out for reading DNA! Plus great illustrations by @ellawatkinsdulaney.bsky.social 000
Reposted by Evan DeTurkKindra Crick 🧩 @kindracrick.com · 18/02/2026Things you happen upon in a small coastal town. I give you, a bowl of preserved moss. As a great admirer of moss in its natural habitat I did not realize that you could preserve it. #moss 🌱 1251
Reposted by Evan DeTurkDimitri Drekonja, MD, MS @dimitridrekonja.bsky.social · 24/01/2026Alex from our time working together, while he was in nursing school. Later, he moved to ICU, working as a nurse to support critically ill Veterans. He had such a great attitude. We’d chat between patients about trying to get in a mountain bike ride together. Will never happen now 626234927709
Evan DeTurk @evandeturk.bsky.social · 23/01/2026At the risk of being classified a domestic terrorist…man fuckkk ICE 000
Reposted by Evan DeTurkNational Academy of Sciences @nasonline.org · 22/01/2026Join us in congratulating Philip J. Kranzusch (@kranzuschlab.bsky.social) of @danafarber.bsky.social and @harvardmed.bsky.social, winner of the 2026 NAS Award in Molecular Biology for his groundbreaking work advancing understanding of innate immunity! www.nasonline.org/award/nas-aw... #NASaward 46011
Reposted by Evan DeTurkDoudna Lab @doudna-lab.bsky.social · 10/01/2026New preprint 👉Doudna x Bryant x Jacobsen x Savage collaboration! Work led by @zehanzhou.bsky.social, I. Saffarian-Deemyad, @honglue.bsky.social, T. Weiss We dissect how stepwise DNA unwinding gates TnpB genome editing, revealing how unwound DNA states enhance cleavage www.biorxiv.org/content/10.6...biorxiv.orgStepwise DNA unwinding gates TnpB genome-editing activityTnpB is a compact RNA-guided endonuclease and evolutionary ancestor of CRISPR-Cas12 that offers a promising platform for genome engineering. However, the genome-editing activity of TnpBs remains limit... 02611
Reposted by Evan DeTurkWalter Olson @walterolson.bsky.social · 03/01/2026Statement from Cato VP Clark Neily: Courts probably won't rule against the rendition. Yet Trump has chosen to bypass the constitutional provisions designed to cabin the president's powers in using force against other countries. And an indictment does not supply him with those powers. 8425157
Evan DeTurk @evandeturk.bsky.social · 19/12/2025Newest round-up is live, feat. the most entertaining, interesting, and informative stuff I read the past few months. This time around, we've got protein design updates, embryo editing companies, planetary cities, and more: scifinow.substack.com/p/the-round-...scifinow.substack.comThe Round-Up #4AI-designed proteins, embryo editing, Coruscant IRL, and more! 010
Reposted by Evan DeTurkMelanie Walsh @mellymeldubs.bsky.social · 11/12/2025Here are the top 10 most popular post-1945 American authors at the Seattle Public Library over the last 20 years. 13522112
Evan DeTurk @evandeturk.bsky.social · 12/12/2025Missed the stream (whoops!) but had a great time watching the film on YT! Bay Area enjoyers - don’t miss it! 010
Reposted by Evan DeTurkBel Esain @isabelesain.bsky.social · 09/12/2025First co-led work from the Doudna lab 🤜🤛 We designed minimal RNA-guided nucleases with AI, and even did Cryo-EM during an earthquake (!) Huge honor working with @petrskopintsev.bsky.social, @evandeturk.bsky.social, Jennifer Doudna and co-authors, everyone at D-Lab and @innovativegenomics.bsky.social 0204
Evan DeTurk @evandeturk.bsky.social · 09/12/2025Excited to share our work designing genome editors with machine learning! 🧬💻 Huge thanks to @petrskopintsev.bsky.social @isabelesain.bsky.social @doudna-lab.bsky.social and all co-authors. Check out the thread for a summary of what we found 👇 0133
Reposted by Evan DeTurkRichard Smyth @rsmythfreelance.bsky.social · 08/11/2025If I see one more stupid Rosalind Franklin take I'm going to lose my mind. Thank god for @matthewcobb.bsky.social and @nccomfort.bsky.social. www.nature.com/articles/d41...nature.comWhat Rosalind Franklin truly contributed to the discovery of DNA’s structureFranklin was no victim in how the DNA double helix was solved. An overlooked letter and an unpublished news article, both written in 1953, reveal that she was an equal player. 16342127
Reposted by Evan DeTurkNathaniel Comfort @nccomfort.bsky.social · 07/11/2025James D. Watson is dead. Stay tuned for some thoughts, based on my research on his biography, to be published soon. While I write that up, y'all can throw tomatoes at this if you like. But I will offer a more nuanced take. www.nytimes.com/2025/11/07/s...nytimes.comJames Watson, Co-Discoverer of the Structure of DNA, Is Dead at 97 118423
Reposted by Evan DeTurkMatthew Cobb @matthewcobb.bsky.social · 04/11/2025Cambridge graffiti, late 1960s. This kind of slogan was generally used for guitar heroes (Clapton, Alvin Lee, Hendrix). In this case, it appears the same person also scrawled 'Keep the lefties out' and 'Enoch is right' (amended by another hand to 'Enoch is a right pratt'). 092
Evan DeTurk @evandeturk.bsky.social · 10/10/2025An overly political CDC has stripped Americans of a one stop shop for health recommendations, but this piece has some advice about how to best replicate it: www.theatlantic.com/health/2025/...theatlantic.comWho to Trust If You Can’t Trust the CDCNo American institution is equipped to replace the agency. But a few trusted resources can help. 000
Evan DeTurk @evandeturk.bsky.social · 09/10/2025If you thought the Animorphs covers were silly, wait till you see 1863 animorphs making fun of Darwin substack.com/@scifinow/no... 000
Evan DeTurk @evandeturk.bsky.social · 06/10/2025For a bit of context, check out the mini-section I wrote on the EO for a Substack news round-up (w/ a bunch of links): scifinow.substack.com/i/165842458/...scifinow.substack.comThe Round-Up #2Dire wolves, AI virologists, sci-fi TV, and much more! 000
Evan DeTurk @evandeturk.bsky.social · 06/10/2025When Trump issued the gain-of-function Executive Order five months ago, people worried it might be applied too broadly. Sarah Stanley's piece for STAT provides evidence supporting that view. Grants flagged for gene knockouts and antibiotic selection markers in tuberculosis.statnews.comThe NIH ordered me to stop my ‘dangerous’ gain-of-function research. It isn’t dangerous at allSafe gain-of-function research is necessary to identify new treatments for diseases like for tuberculosis — but the NIH has imposed unfounded stops. 110
Evan DeTurk @evandeturk.bsky.social · 06/10/2025"Ramsdell couldn’t be reached immediately by the AP or his employer, who thought he might be away on a backpacking trip." Legendary! 000