A free browser extension that marks antibodies cited in a paper with their knockout-controlled validation status, for the application they were used in.

Nucleosomes with their associated modifications organize and regulate the genome. It is unclear how this is integrated with the requirement of replica…

SUMO ligases conjugate the SUMO modifier to target proteins, thus regulating their functions. Here, the authors reveal how DNA and ATP binding by the multiple subunits of the SUMO ligase complex Smc5/...

MpRAD51 links homologous recombination-mediated DNA repair with morphogenesis, revealing an evolutionarily conserved role in maintaining genome stability a

SUMO ligases conjugate the SUMO modifier to target proteins, thus regulating their functions. Here, the authors reveal how DNA and ATP binding by the multiple subunits of the SUMO ligase complex Smc5/6 enable its efficient SUMOylation of genome maintenance proteins.

Transcription factor nanoclusters balance the DNA binding trade-off between weakly binding oligomers and nonspecific condensates.

To cope with the threat of genome instability, cells have evolved an intricate network of mechanisms ranging from cell cycle checkpoints to specialized DNA repair pathways known as the DNA damage res…

Understanding how natural genetic variants affect protein structure and function is central to plant biology. The 1001 Genomes Project has catalogued millions of single nucleotide polymorphisms (SNPs)...

The emergence of the eukaryotes coincided with the diversification of histone proteins and their post-translational modifications by enzymes that constitute the core of eukaryotic chromatin. Yet the e...

The transition from seed to seedling requires chromatin reprogramming. By studying the histone variant H2B.8, the authors show that it organizes silent chromatin in dry seeds and reveal that water upt...

Evidence is presented that crown gall tumors are caused by the incorporation of part of a virulence plasmid carried by the inciting bacterium, Agrobacterium tumefaciens. The rate of reassociation of l...

Folddisco enables protein structural motif search in million scale databases.

There is a particular look people give when you say you are a plant scientist…

Progress has always been made by people who think differently. Neurodiversity helps us think outside the box – and when we do, the sky’s the limit, says space scientist Maggie Aderin

Molecular Breeding - In temperate cereals, vernalization regulates the transition from vegetative to reproductive growth in response to low temperatures. A central component of this pathway is...

Scientists like Eva Dvořák Tomaštíková of the Czech Academy of Sciences chose to contribute to this work for the benefit of science. A. thaliana is key to understanding plant genetics, with implicatio...

A forward-directed screen revealed that Condensin II prevents formation of mitotic anaphase bridges and maintains genome stability under genotoxic stress i