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Nico Claassens

@nicoc-micsynmet.bsky.social
178 followers 112 following 41 posts

Associate Professor Microbial Synthetic Metabolism Wageningen University | Synthetic Biology | Sustainability | working at @mib-wur.bsky.social wur.eu/micsynme

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Reposted by Nico Claassens
Johan Vollenbroek @stichtingmobilisation.nl · 06/06/2026
Enorme hoeveelheden dierlijke eiwitten produceren is niet alleen slecht voor de gezondheid en de planeet, maar zet door de importafhankelijkheid ook onze economie en autonomie op het spel. Hoog tijd dus om hier verandering in te brengen.
decorrespondent.nl
Europa moet anders gaan eten – niet uit idealisme, maar uit veiligheidsoverwegingen
Europa’s inhaalslag op defensie en energie komt op stoom. Maar voor onze voedselvoorziening blijven we afhankelijk van landen waarmee we liever geen zaken doen. De EU kan er niet meer omheen: meer aut...
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Daniel Tamarit @danieltamarit.bsky.social · 22/05/2026
I'm looking for an enthusiastic student to join my team as a PhD candidate on archaeal genome evolution 🦠💻 Work in beautiful Utrecht, at @binfutrecht.bsky.social, an international group full of caring, amazing scientists, and with frequent cake breaks! www.uu.nl/en/organisat... Please share! 🙏
uu.nl
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Nico Claassens @nicoc-micsynmet.bsky.social · 21/05/2026
Early-career researchers do more ‘disruptive’ science than veterans www.nature.com/articles/d41...
nature.com
Early-career researchers do more ‘disruptive’ science than veterans
Analysis of papers from millions of scientists shows that older researchers tend to stick with ideas from their past.
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Reposted by Nico Claassens
Lorenzo Olivi @loreoliv.bsky.social · 11/05/2026
🧵 New pre-print out from my time at @mib-wur.bsky.social showing how the titration of the initiator protein DnaA on the chromosome of E. coli can generate stable DNA replication @hohlbeinlab.bsky.social @nicoc-micsynmet.bsky.social doi.org/10.64898/202...
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Stephan Hacker @stephanhacker2.bsky.social · 06/05/2026
Come and discuss with us about #PhD #Supervision Quality in the #Netherlands at the Profkip Symposium by De Jonge Akademie in the Trippenhuis on May 18th. You will have the chance to engage with members of De Jonge Akademie, @hetpnn.nl, @postdocnl.bsky.social and @apnet.bsky.social.
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Reposted by Nico Claassens
Luc Stultiens @lucstultiens.bsky.social · 06/05/2026
Hoeveel waarschuwingen zijn er nog nodig? De rijken worden rijker, de rest van NL betaalt de rekening. Hoogste tijd voor een forse koerswijziging van dit rechtse beleid!
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 06/05/2026
What we do in the Lab and what we ambition to happen in the (near) future 👇 www.nature.com/articles/d41...
nature.com
Are microbes the future of pollution clean-up?
Synthetic biologists are engineering bacteria to feast on oil, plastic and toxic chemicals.
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Progressief Nederland @progressiefned.bsky.social · 18/03/2026
Duidelijk, toch? Stem vandaag #GroenEnSociaal 💚❤️
1. Eindelijk meer betaalbare woningen 
Iedereen belooft meer woningen, maar als die veel te duur zijn dan heb je er niets aan. Wij kiezen écht voor betaalbaar.
2. Wij kiezen voor groene en gezonde buurten 
Wij werken aan buurten met veel groen, waar je kinderen kunnen spelen en je ‘s avonds veilig over straat kunt.
3. Zorg, onderwijs en zekerheid voor iedereen 
Wij investeren in voorzieningen waar iedereen op kan rekenen. Dat is sociaal beleid waar onze samenleving sterker van wordt.
4. Talent en ervaring overal in Nederland
Wij hebben ervaren bestuurders, sterke volksvertegenwoordigers én jonge talenten om uit te kiezen. Overal in Nederland.
5. Een progressief antwoord op rechtse plannen
Het nieuwe kabinet kiest voor VVD-beleid. Laten wij zorgen voor een progressief antwoord met een groene en sociale gemeente.
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Jacqueline @keuningin.eurosky.social · 16/03/2026
Mooi zo! Nieuwe MacBook is simpel te repareren, met dank aan de EU www.rtl.nl/nieuws/econo...
rtl.nl
Nieuwe MacBook is simpel te repareren, met dank aan de EU
Wie de nieuwe MacBook Neo van Apple openschroeft, ziet iets onverwacht: een batterij die simpel te vervangen is. Dat komt door nieuwe EU-regels, die het makkelijker maken voor consumenten om hun eigen...
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Atletiekvereniging Pallas '67 Wageningen @pallas67.eurosky.social · 11/03/2026
Ok, ik geef toe, ik was Bluesky even vergeten. Maar jullie moeten niet de Night Run Wageningen vergeten. Inschrijven kan nog steeds: nightrunwageningen.nl #wageningen #hardlopen #5km #10km #kidsrun
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Max-Planck-Gesellschaft @maxplanck.de · 08/03/2026
"My motto is: just do it!" We love this interview w/ Maren Nattermann, Research Group Leader @ Max Planck Institute for Terrestrial Microbiology, on Marjory Stephenson (1885–1948), pioneer of chemical microbiology as well as her own path into science www.mpg.de/26210626/mar... #IWD2026
mpg.de
"There isn't one 'single right way' for a career - and it doesn’t have to be a straight line"
Maren Nattermann, Research Group Leader at the Max Planck Institute for Terrestrial Microbiology, on Marjory Stephenson (1885–1948): pioneer of chemical microbiology, whose work on bacterial metabolic...
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Reposted by Nico Claassens
FEMS @femsmicro.org · 19/02/2026
💡 We are inviting you to nominate a woman in microbiology whose work or impact deserves to be seen. Selected nominations will be featured on the FEMS website and across our social media channels on International Women’s Day, 8 March. 👉 Who inspires you? Nominate them by 4 March . buff.ly/AKyMbQD
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embar nitwitzer @amberwiznitzer.bsky.social · 02/02/2026
rust in de portemonnee (geen inkomen)
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Dolf Weijers @dolfweijers.bsky.social · 28/01/2026
www.wur.nl/en/vacancy/f... Become our new colleague (and next door neighbor) and lead a chair/group/department of Biophysics at Wageningen University. Reach out to me for info and please spread!!!
wur.nl
Full Professor and Chair Laboratory of Biophysics
We are looking for a Full Professor in the Biophysics chair group, part of Wageningen University & Research (WUR)
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Johannes Hohlbein @hohlbeinlab.bsky.social · 27/01/2026
The Laboratory of Biophysics at Wageningen University & Research (NL) is looking for a new chair! Details here: www.wur.nl/en/vacancy/f...
wur.nl
Full Professor and Chair Laboratory of Biophysics
We are looking for a Full Professor in the Biophysics chair group, part of Wageningen University & Research (WUR)
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Kees van der Leun @sustainable2050.bsky.social · 10/01/2026
So when we want Dutch government to leave X (I do), we'd better follow them here. A starter pack! Nederlandse overheden: ministeries, provincies, gemeenten Aanvullingen welkom go.bsky.app/V4Bf6mB
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Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺 @ettema.bsky.social · 05/01/2026
I have a postdoc position in metagenomic exploration available in my group. Candidates with documented experience in phylo & metagenomics and preferably with petabase-scale data mining and GLM workflows are encouraged to apply. Come join us! 🧬🦠💻 Please repost Apply here: www.wur.nl/en/vacancy/p...
wur.nl
Postdoctoral researcher Phylogenomics and metagenomics
Are you just as excited as we are about the fascinating world of microorganisms? Do you want to contribute to exploring and genomically characterize novel prokaryotic lineages? Do you have a PhD degre...
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 03/01/2026
Time to leverage SynBio for tacking environmental pollution. But releasing bioengineered microorganisms still raises alarms. A new narrative is badly needed: bacteria for bioremediation are not alien intrusions but laboratory-trained extensions of life’s creativity link.springer.com/10.1038/s443...
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Itai Yanai @itaiyanai.bsky.social · 19/12/2025
Doing a PhD is - at heart - one long discussion with your mentor. The discussion changes over time - with unexpected turns and ups & downs - but through it all is a pair of people discussing a topic endlessly to make sense of it. PhD students: choose someone you like to talk to!
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Michael Wagner @michiwagner4.bsky.social · 19/12/2025
🚨 Postdoctoral Opportunity for Female Scientists🚨 The University of Vienna is awarding at least 20 fully funded 4 year postdoctoral positions to outstanding female scientists Interested? Get in touch via direct message careers.univie.ac.at/en/postdoc/e... #MicroSky 🧪 #PostDoc @univie.ac.at
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Nico Claassens @nicoc-micsynmet.bsky.social · 06/12/2025
For all PhD candidates interested in #syntheticbiology consider our #EMBOSynBio course! Applications open!
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Claudia Vickers @claudiavickers.bsky.social · 27/11/2025
Our new paper is out: we present a quantitative framework to assess how (bio)tech interventions in plant agriculture could meaningfully contribute to climate mitigation. This may be the most important paper I ever publish #SyntheticBiology #ClimateAction #Agriculture #Biochar doi.org/10.1093/plph...
doi.org
Harnessing plant agriculture to mitigate climate change: A framework to evaluate synthetic biology (and other) interventions
The scale of plant agriculture can be used to mitigate climate change, and meaningful targets (synthetic biology and comparators) can be selected to increa
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Nico Claassens @nicoc-micsynmet.bsky.social · 26/11/2025
Opportunity to join the lab of @ettema.bsky.social in our department as postdoc! 👇
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Nico Claassens @nicoc-micsynmet.bsky.social · 25/11/2025
Newest preprint from our lab: a new family of promising synthetic CO2 fixation cycles that may outcompete the Calvin cycle and that Vittorio Rainaldi realized to a great extent in E. coli! Up to 11 heterologous enzymes in a cascade supporting CO2 fixation & growth! www.biorxiv.org/content/10.1...
biorxiv.org
Modular in vivo engineering of the reductive methylaspartate cycles for synthetic CO2 fixation
Biological carbon fixation is currently limited to seven naturally occurring pathways. Synthetic carbon fixation pathways have the potential to surpass aerobic natural pathways in efficiency, but none...
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Nico Claassens @nicoc-micsynmet.bsky.social · 17/10/2025
Great to see our MOSAIC story about an easy, cloning-free efficient protocol for mutating plasmids using recombineering is out now officially and the cover story of ASC Synthetic Biology pubs.acs.org/toc/asbcd6/1... ! Great shoutout to Marijn van den Brink, Tim Althuis and Christophe Danelon!
pubs.acs.org
ACS Synthetic Biology
We introduce MOSAIC, a highly efficient protocol for the editing of plasmids and generation of combinatorial plasmid libraries. This quick protocol employs the single-stranded DNA annealing protein Cs...
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Gerrich @gerrich.bsky.social · 03/10/2025
'hey mela' is the first vegan pregnancy test in the world. Now available in Germany. What could be vegan about it? These tests are based on antibodies that are usually farmed from small rodents kept in cages, infected with hybridoma cells. This test is based on AB expressed from algae!! 🧪
In my left hand I am holding the package of the 'hey mela' pregnancy test. The first vegan pregnancy test in the world. Now available in Germany.
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Reposted by Nico Claassens
Ken Stedman @xtremevirusprof.bsky.social · 12/09/2025
Archaeal Virus Ph.D. project! (With Tessa Quax) www.rug.nl/about-ug/wor...
rug.nl
Vacatures bij de RUG
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Enrico Orsi @eorsi.bsky.social · 12/09/2025
Please repost! Postdoc in adaptive laboratory evolution and C1 synthetic metabolism! Location: DTU Biosustain 🦠🧬🔬 Starting in 01/2026! Fell free to reach out if you have questions! efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
efzu.fa.em2.oraclecloud.com
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Tom van der Lee @tomvanderlee.bsky.social · 09/09/2025
Fijn dat het deze verkiezingen een keer over belastingen gaat. Nu nog zorgen dat de feiten het winnen van de framing. De middenklasse in NL betaalt de belastingkortingen van de allerrijksten. Hoe rijker je bent, hoe lager je belastingdruk. Dit komt door politieke keuzes. Ga stemmen 29 oktober.
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Lorenzo Olivi @loreoliv.bsky.social · 22/08/2025
🧵 Our study on the elusive titration control mechanism of the replication initiator DnaA in Escherichia coli is now out on @natcomms.nature.com‬! @stephkoe.bsky.social @hohlbeinlab.bsky.social‬ @nicoc-micsynmet.bsky.social @ettema.bsky.social‬ @mib-wur.bsky.social doi.org/10.1038/s414...
doi.org
The Escherichia coli replication initiator DnaA is titrated on the chromosome - Nature Communications
A DNA-binding protein, DnaA, regulates the initiation of chromosomal replication in bacteria. Here, Olivi et al. show that the bacterial chromosome sequesters DnaA in a growth rate-dependent manner, s...
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Alex Fedorec @ajfedorec.bsky.social · 13/08/2025
I'm going to be advertising for a few positions in my group in the next couple of months for a big project on synthetic microbial communities. I would love to hear from you if you are interested and I'd also appreciate if everyone could share this far and wide!
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Tom Ellis @proftomellis.bsky.social · 11/08/2025
New paper from our lab on synthetic genome work in yeast is out - Iterative SCRaMbLE for Engineering Synthetic Genome Modules and Chromosomes. Exciting project led by Jane (Xinyu) Lu in our group, now online. t.co/0LuGwgAWlA
t.co
https://www.nature.com/articles/s41467-025-62356-y
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Bart Deplancke @bartdeplancke.bsky.social · 06/08/2025
Outstanding Faculty opportunity in the broad area of 'life sciences engineering' @EPFL School of Life Sciences, open to both junior and senior researchers. We may prefer metabolism-centric applications but remain open to outstanding applications across domains: www.epfl.ch/about/workin...
epfl.ch
Faculty Position in Life Science Engineering
The School of Life Sciences at EPFL invites applications for a faculty position in life science engineering. Appointments will be at Tenure Track Assistant Professor or at Associate Professor level. W...
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Helena Schulz-Mirbach @helenasm.bsky.social · 12/07/2025
#Growth-coupled #selection just got an update ! In the last years, E. coli selection strains for #central , #amino #acid and #energy metabolism intermediates were created by the community. So, we compiled them and revisit the core concepts of growth coupling. www.sciencedirect.com/science/arti...
sciencedirect.com
Escherichia coli selection strains for growth-coupled metabolic engineering
Synthetic metabolism has the potential to transform carbon capture, bioremediation, or bioproduction strategies. To transfer metabolic designs from an…
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Matthias Heinemann @matthiasheinemann.bsky.social · 27/06/2025
Proteins of amino acid metabolism form large structures and determine diffusion in the cytoplasm! Our 7-year-long tour-de-force is now out on Bioxriv www.biorxiv.org/content/10.1... Thanks everyone involved! And especially to Jose Losa who pioneered this!
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David Ho @davidho.bsky.social · 22/06/2025
I get annoyed at the narrative that all the awareness and work on climate change hasn't done anything. Yes, global CO₂ emissions indeed continue to climb, but we don't know the counterfactual. When I was in grad school, we were on track for 5°C of warming. Now it's below 3°C. That's progress.
A line chart titled “Annual CO₂ emissions” shows the global carbon dioxide emissions from fossil fuels and industry from 1950 to 2023. The y-axis represents emissions in billions of tonnes (t), ranging from 0 to 40 billion t. The x-axis covers the years from 1950 to 2023.

The chart presents a steady increase in emissions from approximately 5 billion tonnes in 1950 to over 36 billion tonnes in 2023. Key features include:

A consistent upward trend from 1950 through the early 1970s.

A brief plateau and dip around 1980–1983.

A strong growth trend resuming in the late 1980s.

A sharp increase during the 2000s.

A slight drop around 2008–2009, likely due to the global financial crisis.

A major dip in 2020, attributed to the COVID-19 pandemic.

A rapid rebound in emissions after 2020, continuing the upward trend to a new high in 2023.

A blue line labeled “World” traces these changes over time.

Below the chart, the data source is listed as the Global Carbon Budget (2024), and the graphic is credited to OurWorldInData.org with a Creative Commons license (CC BY). A footnote explains that the data includes emissions from coal, oil, gas, flaring, cement, and steel, but excludes land-use changes such as deforestation.
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Detmer Sipkema @detmersipkema.bsky.social · 22/05/2025
Bachelor open avond Wageningen Universiteit: 5 juni van 16-21h www.wur.nl/nl/onderwijs...
wur.nl
Bachelor Open Avond
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Daniel Tamarit @danieltamarit.bsky.social · 14/05/2025
New vacancy in my team! PhD student position on microbial genome evolution, focusing on the evolutionary principles underlying bacterial genome architecture. Please repost and share with talented MSc students in #evobio, bioinformatics or related :) www.uu.nl/en/organisat... #MEvoSky #MicroSky
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Detmer Sipkema @detmersipkema.bsky.social · 14/05/2025
Very nice lab to do a PhD
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Nico Claassens @nicoc-micsynmet.bsky.social · 12/05/2025
Ik vind deze campagne erg belangrijk - doe je ook mee? actie.degoedezaak.org/petitions/mo...
actie.degoedezaak.org
Teken voor een motie van wantrouwen tegen minister Faber
De ondertekenaars van deze petitie laten zien dat het Nederlandse volk klaar is met een minister die de hand boven het hoofd gehouden wordt om de coalitie bij elkaar te houden. Dit terwijl de minister...
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Sebastian S. Cocioba @atinygreencell.bsky.social · 02/05/2025
I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs. Plant, Bacterial, Archaeal Non-model Bioeng Custom Lab Hardware Turn Key Genetic Design Please repost for reach 💚
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Tom Ellis @proftomellis.bsky.social · 02/05/2025
>4 megabase synthetic genome assembled in E.coli with 7 of life's 64 codons removed throughout. A new landmark for synthetic genomes. I wonder how well this little cell grows...
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Cees Dekker @ceesdekker.bsky.social · 13/03/2025
We have 3 openings for ambitious postdocs or PhD students in our #CDlab - for exciting single-molecule biophysics research on nuclear pores, peroxisomes, or archaeal divisomes. Check it out and apply: ceesdekkerlab.nl/come-join-us/ RT=nice!
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Tom van der Lee @tomvanderlee.bsky.social · 19/04/2025
Wij zeggen: Er is wél een rode lijn. Onze advertentie, vandaag in het AD, Trouw en de Volkskrant. Deel dit statement en help ons om meer partijen te overtuigen! 👇🏼👊🏼
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European Synthetic Biology Society @eusynbios.org · 01/04/2025
✨ Our #SynBio map is growing! 🌍🔬 Excited to welcome 3 new labs to the #EUSynBioMap, connecting #SyntheticBiology labs and associations across Europe! Find out more here 👉 www.linkedin.com/posts/eusynb... ⭐️ Want to add your lab? Contact us!
linkedin.com
#eusynbiomap #syntheticbiology #europe #bristol #barcelona #leeds #synbio… | European Synthetic Biology Society (EUSynBioS)
✨ 𝗢𝘂𝗿 𝗦𝘆𝗻𝘁𝗵𝗲𝘁𝗶𝗰 𝗕𝗶𝗼𝗹𝗼𝗴𝘆 𝗠𝗮𝗽 𝗶𝘀 𝗴𝗿𝗼𝘄𝗶𝗻𝗴! 🌍⁣ ⁣ We’re excited to welcome 3 new labs to our #EUSynBioMap, our initiative dedicated…
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Nico Claassens @nicoc-micsynmet.bsky.social · 09/04/2025
Ik vind deze campagne erg belangrijk - doe je ook mee? actie.degoedezaak.org/petitions/ee...
actie.degoedezaak.org
Eerlijkere loonverdeling in het hoger onderwijs
Zeker nu minister Bruins van OCW de grootste bezuinigingen op het hoger onderwijs in decennia heeft aangekondigd is het essentieel dat de sector zich niet tegen elkaar uit laat spelen en solidair met ...
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Detmer Sipkema @detmersipkema.bsky.social · 07/04/2025
NTR weg......? Het lijkt wel alsof we ook een DOGE hebben. Teken de petitie als protest. Heb ik ook net gedaan.
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Andrew D Hanson @adhansonlab.bsky.social · 05/04/2025
Sam Lovat, Elad Noor, Ron Milo run the numbers on #VerticalFarming to get ⚡️ cost ≈$10/kg dry plant matter. Which explains why it's viable only for high-value 🥬 ('fru-fru baby lettuce') Vertical farming limitations & potential demonstrated by back-of-the-envelope calculations doi.org/10.1093/plph...
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SUN-PERFORM @sunperform.eu · 01/04/2025
During our recent consortium meeting in Marburg, we visited the cutting-edge research facilities at @mpimicrobiomarburg.bsky.social. Thank you, Nicole Paczia & Timo Glatter, for showing us around your Metabolomics and Proteomics installations! 🧪 #Microbiology #SynBio #SolarFuels #HorizonEU
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SUN-PERFORM @sunperform.eu · 28/03/2025
Our partners @w-u-r.bsky.social and @mpimicrobiomarburg.bsky.social demonstrated how synthetic metabolism can outperform the Calvin cycle—nature’s mechanism for CO2 fixation. Read the full, open-access Nature Microbiology article at doi.org/10.1038/s415... #SyntheticBiology #MetabolicEngineering
doi.org
One-carbon fixation via the synthetic reductive glycine pathway exceeds yield of the Calvin cycle - Nature Microbiology
An engineered one-carbon-fixation pathway increases biomass yields of Cupriavidus necator compared with the Calvin cycle and can support future, sustainable bio-based production.
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