An experiment in sea slugs suggests transcriptional changes might fade after 24 hours.

A complete guide to the NSF Graduate Research Fellowship from a coach who's supported 25+ GRFP applicants. Covers eligibility, the application, review criteria, and the major FY2026 changes — includin...

Post-transcriptional regulation of mRNA translation was explored using Ribo-STAMP and single-cell RNA sequencing to reveal cell-type-specific and isoform-specific translation patterns across hipp...

Here it is: your starter guide for developing the knowledge and skills you’ll need throughout your career. Compiled by our expert staff, here’s what this handbook covers:Overview of the…

A life-sciences job in Boston used to be a sure path to a high-paying career, but empty labs and unemployed grads now herald tougher times in the city.

In a memo obtained by STAT, the NIH gives specific steps on how grant reviewers can check for alignment with administration priorities.

A new NSF initiative will support teams of researchers, a departure from the traditional practice of giving grants to individual professors.

Sarah Tabrizi is part of Nature’s 10, a list of people who shaped science in 2025.

The first-in-class small molecule Jascayd targets a fibrotic signaling cascade, offering new hope in a stagnant therapeutic field, as several other programs near maturity.

Virus-like particles are engineered to edit human hematopoietic cells in vivo.

The chaos created by the freezing and termination of billions of dollars of research grants has left trans academics especially vulnerable.

Colors of the Brain colorsofthebrain.comcolorsofthebrain@gmail.comOUR MISSIONColors of the Brain is committed to diversifying STEM graduate education and academia. We support undergraduates from histo...

Nature Biotechnology - Designer voltage-gated anion channels suppress neuronal firing

Over 74,000 people enrolled in experiments have been affected by the NIH's funding cuts, according to a new report.

An optimized pipeline for functional ultrasound localization microscopy is safely and non-invasively applied to detect and characterize early microvascular alterations with high spatial and temporal r...

RNA-binding motifs in eukaryotic proteins are presented in a comprehensive resource.

Budding academics are delaying their graduate studies, continuing them abroad, or forgoing them entirely.

Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of zimisle...

A federal judge says it was illegal for the Trump administration to cancel several hundred research grants issued by the National Institutes of Health.

Nature Reviews Microbiology, Published online: 14 April 2025; doi:10.1038/s41579-025-01182-xThis study reports the identification of a ribosome-targeting lasso peptide that acts on a new ribosomal binding site.

Grassroots organizations, led by graduate students and postdoctoral researchers, are stepping up to provide neuroscience career training and guidance for students from marginalized backgrounds—and…

US National Science Foundation announces lowest number of Graduate Research Fellowship Programme recipients in 15 years.

A hallmark of pulmonary fibrosis is the aberrant activation of lung fibroblasts into pathological fibroblasts that produce excessive extracellular matrix1–3. Thus, the identification of key regulators that promote the generation of pathological fibroblasts can inform the development of effective countermeasures against disease progression. Here we use two mouse models of pulmonary fibrosis to show that LEPR+ fibroblasts that arise during alveologenesis include SCUBE2+ alveolar fibroblasts as a major constituent. These alveolar fibroblasts in turn contribute substantially to CTHRC1+POSTN+ pathological fibroblasts. Genetic ablation of POSTN+ pathological fibroblasts attenuates fibrosis. Comprehensive analyses of scRNA-seq and scATAC-seq data reveal that RUNX2 is a key regulator of the expression of fibrotic genes. Consistently, conditional deletion of Runx2 with LeprcreERT2 or Scube2creERT2 reduces the generation of pathological fibroblasts, extracellular matrix deposition and pulmonary

Nature Reviews Molecular Cell Biology, Published online: 28 March 2025; doi:10.1038/s41580-025-00844-1Carrie Bernecky describes why the first solved structure of RNA polymerase II was important for transcription researchers, structural biologists, and beyond.

At "Stand Up for Science" rallies across the U.S., scientists and their supporters protested Trump administration actions affecting research.

Students and early-career professionals in lab research, biology, neuroscience, immunology, and others should apply for our internships and fellowships.

Blindness afflicts ~39 million people worldwide. Retinal ganglion cells are unable to regenerate, making this condition irreversible in many cases. Whole-eye transplantation (WET) provides the opportu...