This study demonstrates that cytoskeletal state at the onset of directed differentiation impacts the exit of stem cells from pluripotency and downstream lineage specification. These findings are utili...

BMC Methods - Pancreatic islet transplantation is a promising therapeutic strategy to restore insulin independence in patients with type 1 diabetes mellitus. In addition to primary human islets,...

Tai Lee of Millman Lab Most 15-year-olds are figuring out who they want to be. Tai Le was doing that too – just 9,000 miles from home, on his own. At just 15, Le immigrated to the United States fro…

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Glioblastoma (GBM) is characterized by a high degree of heterogeneity and plasticity due to interplay with neural developmental programs. Here, the authors develop a model of GBM by introducing sequen...

Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by the T cell-mediated destruction of insulin-secreting pancreatic β cells, leaving patie...

Pathways to Advanced Scientific Skills through Postdoctoral Research Training (PASSPoRT) Register Here Thank you for considering WashU for your...

Our team is walking and raising funds to support the most promising, cutting-edge science to create a world without T1D. Join us!

Veronese-Paniagua et al. demonstrate that coxsackievirus B3 infects all primary human islet cell types and elicits distinct cell-type-specific transcriptional and mitochondrial responses. They identif...

This article summarizes the current understanding of the heterogeneity of type 1 diabetes from a June 2024 international Expert Forum organized by the edit

The need to suppress a patient’s immune system after the transplantation of allogeneic cells is associated with wide-ranging side effects. We report the outcomes of transplantation of genetically m...

By Erika Brown – July 7, 2025 Research Technicians are the backbone of research laboratories. They actively participate in various projects, acquiring knowledge that they can apply in their f…

Growth factors enhance survival and integration of transplanted Mesenchymal Stromal Cells (MSC), but successful supplementation often requires supraphysiological growth factor doses, risking off-targ....

Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of zimisle...

Application Application window is now open. Due Date June 15th, 2025 – Current RFA details The Center of Regenerative Medicine (CRM) at WashU invites applications for the Rita Levi-Montalcini…

Islet cell replacement therapies have evolved as a viable treatment option for type 1 diabetes complicated by problematic hypoglycemia and glycemic labilit

The Investor Relations website contains information about Vertex Pharmaceuticals's business for stockholders, potential investors, and financial analysts.

In his resignation letter, Dr. Peter Marks cited ‘misinformation and lies’ from Health and Human Services Secretary RFK Jr.

Penn notified department chairs that it will cut admissions across graduate programs — a decision faculty members say will force them to rescind offers from newly-accepted students.

Renee Wegrzyn, Ph.D., the inaugural head of the Advanced Research Projects Agency for Health (ARPA-H), has been let go, a Department of Health and Human Services spokesperson confirmed with Fierce | R...