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Stanford researchers have developed a technology that delivers RNA to damaged neurons and stimulates regrowth – paving the way for potential treatments targeting neurodegenerative diseases like ALS…

CRISPR-TO, a system for programmable control of spatial localization of cellular RNAs, is presented and enables functional investigation of endogenous RNA localization in diverse living cells.

Stanford bioengineer Stanley Qi is developing advanced gene-editing tools to treat life-threatening diseases and slow the onset of neurological aging.

Stanford bioengineer Stanley Qi is developing advanced gene-editing tools to treat life-threatening diseases and slow the onset of neurological aging.

Tissue-resident macrophages (TRMs) are innate immune cells that participate in tissue development, homeostasis, and immune surveillance. Extensive efforts have been made to recapitulate TRM developmen...

The Alzheimer's Association calls on HHS Secretary Kennedy to stop dangerous fabrications about the state of Alzheimer’s and dementia research.

Harvard University is devoted to excellence in teaching, learning, and research, and to developing leaders who make a difference globally.

A high efficiency binary format for sequencing data - ArcInstitute/binseq

Thousands of tons of trash are being dumped at unauthorized waste sites across the Antelope Valley, lawsuits claim. Authorities say they are aware but have done little to stop it.

Subcellular RNA organization can affect critical cellular functions. However, our understanding of RNA microenvironments, particularly biomolecular condensates, remains limited, largely due to a lack ...

By mapping SWI/SNF complex subfamilies in the melanocytic lineage, Grossi and Nguyen et al. find that PBAF-only sites harbor PRC1/2 modifications and the repressive transcription factor REST. PBAF is ...

While high and stable transgene expression can be achieved in undifferentiated pluripotent stem cells, conventional transgene expression systems are often silenced upon differentiation. Silencing occu...

Oligo-LiveFISH is an approach that can track diverse genomic loci at high spatial (20 nm) and temporal (50 ms) resolution and can work in diverse cell types, including primary cells. Combined with sup...

Changes to the female brain during menopause, together with social and cultural factors, might affect disease risk.

Expanded polystyrene foam, the white fluffy plastic in styrofoam, was banned in food service ware on Jan. 1. But shoppers in CA say its still on the shelves.

Podcast · Stephanie Wankowicz · A deep dive into scientific discovery and the process of doing science, hosted by Stephanie Wankowicz and James Fraser.

The US government has begun slashing US$400 million in research grants at Columbia University over pro-Palestinian campus protests.

As Elon Musk's DOGE continues to plunder the federal government, even the TSA's bomb-sniffing K9 units aren't safe.

An NIH funding policy is misguided and damaging

Pluripotent stem cells are susceptible to acquiring detrimental epigenetic abnormalities, posing a hurdle to their safe use in biomedical applications. Using pluripotent cells with defined genetic backgrounds, Stadtfeld and colleagues show that genetic variation is a major driver of epigenome stability and identify candidate regulators. These findings will enable novel approaches to stabilize the epigenome of pluripotent cells in culture.

A new H5N1 bird flu mutation has appeared in a cluster of infected dairy cows. It's a genetic change that scientists say could not only make the virus more lethal, but increase its spread between mamm...

Using a 3D co-culture system of iPSC-derived neurons and glia, termed iAssembloids, combined with CRISPRi-based screening, Li et al. investigate the effect of glial cells on neuronal activity and surv...

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Aggregation of the protein tau defines tauopathies, which include Alzheimer's disease and frontotemporal dementia. Specific neuronal subtypes are selectively vulnerable to tau aggregation and subseque...