Why the GPO?  The GPO offers a rare and remarkable opportunity. Many of the great academies of Europe, such as the Royal Academy in London, the Repin Academy in St. Petersburg, the Ecole de beaux...

NLRP3 inflammasome activation is critical for the induction of protective immunity, but molecular insights are still lacking. Here, the authors express NLRP3 variants targeted to different cellular lo...

PhD Project - Understanding how high plasma soluble urokinase plasminogen activator receptor (suPAR) predicts poor outcome in patients with ARDS. at Queen’s University Belfast, listed on FindAPhD.com

TBK1 and IKKe prevent premature cell death by limiting the activity of multiple death pathways in myeloid cells.

Injection of YopJ by Yersinia pseudotuberculosis triggers RIPK1-dependent caspase-8 and GSDMD activation in murine macrophages; however, how macrophages defend against Yersinia when caspase-8 or YopJ ...

Nature Immunology - Pyroptotic cell death results in inflammation. Here the authors find that F-actin-rich structures formed during macrophage pyroptosis persist after cell death to activate...

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Inflammasomes are nucleated by receptors that become activated upon cellular stresses including ioni