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Jiri Hofbrucker

@deepjdog.bsky.social
570 followers 556 following 25 posts

Empowering neuroscientists with fiber-based microscopic systems for imaging at any brain depth CTO at DeepEn, @deepen-imaging.bsky.social ( deepen-imaging.com )

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Reposted by Jiri Hofbrucker
Tatsuya Nobori @tatsuyanobori.bsky.social · 11/08/2026
We're hiring 🔬🌱🦠 We're looking for someone with confocal microscopy expertise to join our work on plant–microbe interactions @thesainsburylab.bsky.social . A whole new suite of genetically encoded reporters + 3D spatial gene expression tools like PHYTOMap and more. Please share!
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The Transmitter @thetransmitter.bsky.social · 10/07/2026
When another mouse goes from friend to foe, connections from the hippocampus to the amygdala strengthen. #neuroskyence By @natmesanash.bsky.social www.thetransmitter.org/social-behav...
thetransmitter.org
Friend to foe: How the brain updates feelings toward others
A specific pathway reassigns emotional valence to a known mouse, while the hippocampus’s own representation of that animal’s identity remains stable.
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Reposted by Jiri Hofbrucker
Jiri Hofbrucker @deepjdog.bsky.social · 01/07/2026
🧠🔬Really looking forward to joining the #FENS2026 in lovely Barcelona! The whole DeepEn team is excited to discuss holographic microendoscopy for deep brain imaging at Booth #64. Stop by for a chat—we'd love to meet you! #neuroimaging #microscopy #neuroscience
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Jiri Hofbrucker @deepjdog.bsky.social · 01/07/2026
🧠🔬Really looking forward to joining the #FENS2026 in lovely Barcelona! The whole DeepEn team is excited to discuss holographic microendoscopy for deep brain imaging at Booth #64. Stop by for a chat—we'd love to meet you! #neuroimaging #microscopy #neuroscience
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Reposted by Jiri Hofbrucker
Matthijs Dorst @mattneuro.dorst-lab.org · 17/05/2026
You ever get the feeling you may have slightly, massively overengineered something? Still need to add the electronics, but these should turn into some handy little Arduino-powered training rigs.
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Reposted by Jiri Hofbrucker
Marco A. Maximo Prado @maximoprado.bsky.social · 08/05/2026
#fluorescenceFriday looking at cholinergic neurons and processes in 3 D with Chat in yellow and VAChT magenta by the @mind-western.bsky.social team and Ariel Burrowes
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Reposted by Jiri Hofbrucker
Sheffield Hearing Group @hearingshef.bsky.social · 27/04/2026
Happy #MicroscopyMonday everyone!🔬🧪 Today's stunning image comes from Lillian! The image shows the apical part of a 9-day old mouse cochlea with myosin7a ❤️ staining the hair cells, DAPI 💙 staining the nucleus and a ✨mysterious✨ green protein💚👀 #NeuroSkyence #HearingResearch
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Primate Behavioral Ecology @primbehavecol.bsky.social · 25/11/2025
Come and join our lab! We have TWO fully funded PhD positions AND a paid field assistant opportunity in our Behavioral Ecology group @uni-goettingen.de & @primatenzentrum.bsky.social. Projects will be part of @rtg2906-curiosity.bsky.social & @sfb1528.bsky.social!! Details in thread. Please re-post!
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NeuroNexus Technologies @neuronexustech.bsky.social · 01/04/2026
Mini Matrix enables high-density 3D recordings in small animals, providing access to large neuronal populations for acute or chronic studies. 32–128 channels for rec & stim Automated, low-risk implantation Modular, customizable configurations Optogenetics-compatible
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TRIDENT Preclinical Trials @tridentpct.bsky.social · 06/03/2026
🎶Let’s dance…but make it light sheet. For #FluorescenceFriday, the team is looking at blood vessels in brilliant color🧠. Beautiful imaging by @mind-western.bsky.social, @shahrzadbahrampour.bsky.social, @nadiahaghbinphd.bsky.social, and Vladislav Novikov! When our science moves, it grooves. 🔬😎
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Hao Yin @haoyin.bsky.social · 14/03/2026
Optical clearing & time-lapse fluorescent imaging of Live mouse Brain (up to 800 μm of depth)🤯 An acute olfactory bulb slice(P11) loaded with GCaMP6f (Ca2+ sensor) was imaged with #2PM at a depth of 150 μm during clearing with SeeDB-Live👹 #NatMethods 2026 www.nature.com/articles/s41...
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Jiri Hofbrucker @deepjdog.bsky.social · 16/03/2026
@deepen-imaging.bsky.social will be exhibiting at the Bonn Brain Conference 23–25 March 2026 at #dzne #bonn. Come meet us to learn more about the latest developments in holographic microendoscopy and how you can use it to access deep brain regions. See you in Bonn! #Neuroscience #Neurotech
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Reposted by Jiri Hofbrucker
Network Glia | European Glia Meeting @gliameeting.bsky.social · 19/02/2026
Glia in Focus 🔬 A series highlighting the beauty of glial cells. Confocal image (64x) of rodent brain tissue (P1) showing microglia (Iba1, magenta) near a CMV-infected microglial cell (green). Image: @Sarah Tarhini #GliaInFocus #Microglia #ConfocalMicroscopy #BrainDevelopment #ScienceArt
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Jiri Hofbrucker @deepjdog.bsky.social · 12/02/2026
As Neurophotonics developers, we love learning about in vivo imaging directly from scientists. We’re recruiting 20participants for our in vivo imaging survey. ⏱️ ~10 min 🎁 Free neuron socks Work with in vivo animal imaging? Contact us at info@deepen-imaging.com. #neuroscience #microscopy#neuroimaging
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Jiri Hofbrucker @deepjdog.bsky.social · 12/02/2026
As Neurophotonics developers, we love learning about in vivo imaging directly from scientists. We’re recruiting 20participants for our in vivo imaging survey. ⏱️ ~10 min 🎁 Free neuron socks Work with in vivo animal imaging? Contact us at info@deepen-imaging.com. #neuroscience #microscopy#neuroimaging
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Lilian Weber @lilweb.bsky.social · 18/12/2025
🚀 Excited to announce that I'm looking for people (PhD/Postdoc) to join my Cognitive Modelling group @uniosnabrueck.bsky.social. If you want to join a genuinely curious, welcoming and inclusive community of Coxis, apply here: tinyurl.com/coxijobs Please RT - deadline is Jan 4‼️
uni-osnabrueck.de
192 FB 8/IKW Research Associate (m/f/d), Institute of Cognitive Science: Uni Osnabrück
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deepen-imaging.bsky.social @deepen-imaging.bsky.social · 20/11/2025
#SfN25 is now over! Thanks to all the lovely people who came to our booth and shared their science stories with us! It was an inspirational week for DeepEn! Thanks to @sfn.org for an extraordinary meeting!
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allen institute @alleninstitute.org · 05/12/2025
🧠📢 New preprint alert Large-scale ephys is exploding but spike sorting remains the computational bottleneck. A 2-hr, 6-probe Neuropixels 2.0 Quad Base session can take over a week to sort on a single machine. Here's a better solution. 🧵 #neuroskyence #compneurosky
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deepen-imaging.bsky.social @deepen-imaging.bsky.social · 17/11/2025
DeepEn is at NEUROSCIENCE 2025 #SfN25 ! 🧠🔬🌴 Come to our BOOTH #3027, check our microendoscope for deep brain imaging with sub cellular resolution and minimal tissue damage. And meet Hana, Tomas, Patrick and Jiri! #neuroimaging
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Jiri Hofbrucker @deepjdog.bsky.social · 07/11/2025
I'm excited to join #SfN2025 next week. Stop by booth #3027 to connect and learn more about structural and functional imaging in-vivo anywhere in the brain! I’d love to hear about your research and ideas! Looking forward to meeting you there.
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Reposted by Jiri Hofbrucker
Emily R. Trunnell, Ph.D. @ertrunnell.bsky.social · 03/11/2025
This new miBrain model from MIT has it all: 🧠 Neurons, microglia, oligodendroglia, astrocytes, pericytes, & brain microvascular endothelial cells ⚙️ Key features & functions of the human brain 👩‍👦 Specificity to individual donors 🧬 Customizability via gene editing 📈 Scalability for large projects
Image from the MIT Picower article, "MIT invents human brain model with six major cell types to enable personalized disease research, drug discovery" with the following caption: “Cyan staining shows each of the six major cell types [pericytes, astrocytes, endothelial cells, neurons, oligodendrocytes, and microglia] integrated in a miBrain culture.” The original image appeared in Figure 1 of the PNAS article, “Engineered 3D immuno-glial-neurovascular human miBrain model” (10.1073/pnas.2511596122) by Stanton et al.
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Jiri Hofbrucker @deepjdog.bsky.social · 07/10/2025
🧠What do neuroscientists think of DeepEn's holographic microendoscope? How can they use it to study learning and memory processes? Can it enable voltage imaging in deep brain structures to study processes behind neuronal firing? ⭐ Check the Nature’s article: www.nature.com/articles/d42...
nature.com
High-resolution insights from the deep brain
Discover the world’s best science and medicine | Nature.com
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Sanja Mikulovic @smikulovic.bsky.social · 04/09/2025
Excited to share we’ve been awarded the ERC StG 🎉 for our project ProSocial, studying neural mechanisms of prosocial behavior in health & disease. Huge thanks to my group for their amazing work & to great colleagues for their support! Positions opening soon—reach out if interested!
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Jiri Hofbrucker @deepjdog.bsky.social · 02/09/2025
Are you the kind of neuroscientist who scripts analysis or can’t resist tinkering with hardware? At DeepEn we’re building a fluorescence microscope to image deep in the brain through a single optical fiber. Join us to hack the future of neuroimaging: #ScienceJob www.linkedin.com/jobs/view/42...
linkedin.com
DeepEn hiring Neuroscience Imaging Scientist (Microscopy + Applications) in Jena, Thuringia, Germany | LinkedIn
Posted 8:01:32 PM. DeepEn develops minimally invasive microendoscopes for neuroscience applications. We transform a…See this and similar jobs on LinkedIn.
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German BioImaging @gerbi-gmb.de · 01/09/2025
⏰ Reminder: The early bird registration and abstract submission for our 5th Day of Intravital Microscopy close on September 5! Don’t miss your chance to join us in Tübingen on 18–19 Sept. Secure your spot today! 👉 bit.ly/3IOlJtJ
bit.ly
5th Day of Intravital Microscopy - German BioImaging
Intravital microscopy (IVM) enables the observation and precise quantification of cellular processes within native tissue microenvironments, with resolutions unmatched by other techniques. This powerf...
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Reposted by Jiri Hofbrucker
Danai Riga @danai-lama.bsky.social · 01/09/2025
Beautiful work!
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Tobias Ackels @tobiasackels.bsky.social · 11/06/2025
Fun collaborative work together with the amazing lab of @sophiesteculorum.bsky.social now published!
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Melike Eren @neurowithmelike.bsky.social · 07/07/2025
www.nature.com/articles/s41...
nature.com
A mouse brain stereotaxic topographic atlas with isotropic 1-μm resolution - Nature
A stereotaxic atlas of the whole mouse brain, based on a Nissl-stained cytoarchitecture dataset with isotropic 1-μm resolution, achieved through continuous micro-optical sectioning tomography, promise...
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Melissa Cooper, PhD @melcooperphd.bsky.social · 14/05/2025
Hippocampal vasculature is so pretty 😍 (mouse hippocampus perfused with Tomato Lectin and cleared) #Neuroscience #Microscopy
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Marc Aurel Busche @marcaurelbusche.bsky.social · 08/05/2025
Where does Alzheimer’s begin in the brain? Our study in @cp-neuron.bsky.social shows that the earliest amyloid-related neuronal dysfunction emerges selectively in deep cortical layers (layers 5/6), targeting fast-spiking parvalbumin interneurons via reductions in NPTX2. www.cell.com/neuron/fullt...
cell.com
Selectively vulnerable deep cortical layer 5/6 fast-spiking interneurons in Alzheimer’s disease models in vivo
Papanikolaou et al. show that deep-layer cortical neurons exhibit abnormally prolonged Ca2+ transients early in Alzheimer’s mouse models. This is linked to suppressed activity and altered tuning of fa...
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Nikita Vladimirov @nvladimus.bsky.social · 20/01/2025
Please welcome our official #mesoSPIM channel on this platform, @mesospim.bsky.social. Repost is appreciated!
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Petra Mocellin @petramoce.bsky.social · 01/05/2025
Too excited not to share this beauty! #fluorescenceFriday (but a day earlier) TH staining in cyan Virus injection in magenta Zona Incerta is definitely a tough cookie 🍪 but getting there!
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6th Neurons in Action Conference @neuronsinactionpl.bsky.social · 30/03/2025
🧠 GABA! 🔬✨Explore groundbreaking research on the GABAergic system and its role in health and disease in humans and rodents. Learn more by joining us #NeuronsInAction2025! 📍the Nencki Institute, Warsaw, Poland 📅 27-31 May, 2025 #nia2025 #neuronsinaction2025 #neuroscience #brain #nenckiinstitute
A picture of a gigaseal during electrophysiological recording in neuron.
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Markus Fendt @mfendt.bsky.social · 28/03/2025
Excellent Norbert Elsner Lecture by Rui Costa @ruimcosta.bsky.social, Göttingen Meeting of @neurowissg.bsky.social
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deepen-imaging.bsky.social @deepen-imaging.bsky.social · 20/03/2025
📣 1 week to go! Get ready for a LIVE DEMO of our Holographic Microendoscope for high resolution deep brain imaging 🧠 🔬 📍at the 16th Göttingen Meeting of the German Neuroscience Society Come to our booth and tell us about your research ideas! #NWG2025 #GöttingenMeeting #Neuroscience
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Brianna George, PhD @briannaegeorge.bsky.social · 14/03/2025
Just so happened to see this beauty today while recording in Kash Lab @superkash.bsky.social. Happy #FluorescenceFriday 🤩🔬
In vivo image captured of a neuron labeled with a calcium indicator
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allen institute @alleninstitute.org · 13/03/2025
Happy #BrainAwarenessWeek! Join this international celebration of the brain with this visual exploration of its makeup and neighborhoods: alleninstitute.org/news/what-ar... 🧠📈 @danafoundation.bsky.social
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Confocal NL @microscopy.confocalnl.com · 10/03/2025
Do you want to join a great team and work on cutting-edge confocal microscopy systems? Join us at Confocal NL as a Product Application Specialist and help researchers globally accelerate their discoveries with our disruptive technology! Apply here: confocal.recruitee.com/o/product-ap...
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MAC lab @maclab.bsky.social · 10/03/2025
The MAC lab is hiring a full-time lab manager to start in June! You will have the opportunity to conduct research projects relating to long-term memory and concept knowledge (methods include online and in-person behavioral experiments, fMRI, TMS). Apply by March 26 careers.drexel.edu/cw/en-us/job...
memoryandconceptslab.org
MAC lab
How does our prior knowledge impact how we learn new information? How do memories change over time? We use cognitive neuroscience methods to understand how the brain stores, organizes, and transforms ...
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NERF @nerflabs.bsky.social · 11/02/2025
As part of #NEUROGATE, the Haesler lab is helping develop a holographic endoscope for high-resolution, deep-brain imaging. Supported by a €2.5M EIC grant, this ultra-thin fiber technology could transform neuroscience & neurotech. nerf.be/en/news#/new...
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Czech Academy of Sciences @czechacademy.bsky.social · 03/02/2025
The research team from @leibnizipht.bsky.social, DeepEn, the Institute of Scientific Instruments @czechacademy.bsky.social & @nerflabs.bsky.social is developing this innovative imaging technology to visualize neuronal processes in living organisms with high precision.
“With NEUROGATE, we are taking it to the next level to study neuronal activity under natural conditions with unprecedented precision. These findings could significantly expand our understanding of neurological diseases.” Tomáš Čižmár, Institute of Scientific Instruments of the CAS
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Deutsche Gesellschaft für Neurologie (DGN) e.V. @dgn-ev.bsky.social · 07/03/2025
Dr. Jörg Philipps erhält den Robert Wartenberg-Preis 2025 für seine Arbeiten zu diagnostischen Anwendungen des hochauflösenden Nervenultraschalls in der #Neurologie. Herzlichen Glückwunsch! 👉 dgn.org/artikel/robe... #neuroskyence Foto:© DGN/Claudius Pflug
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SVI Huygens @svi.nl · 06/03/2025
Happy to provide a #TIM2025 Workshop and present together with Dr. Peter Hemmerich, from the CF Imaging of the Leibniz Institute on Aging – FLI, image Quality Control, restoration, deconvolution, denoising, and analysis of confocal and STED data. #microscopy #science
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Jiri Hofbrucker @deepjdog.bsky.social · 06/03/2025
Excited to attend the 16th Göttingen Meeting of the @neurowissg.bsky.social in three weeks! Looking forward to insightful discussions and cutting-edge research. If you're attending, let’s connect—I’d love to catch up in person! See you in Göttingen! 🚀🔬 #Neuroscience #GöttingenMeeting #NWG2025
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Denis Jabaudon @djabaudon.bsky.social · 02/02/2025
🧠Job Opening!🧠 We are opening 2️⃣! positions – bioinformatics / molecular biology – in a project studying how temporal patterns set up connectivity in human brain tissue. @institutimagine.bsky.social. Full details below, contact me for details if interested. And please retweet (re-bluesky?)!
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Natalie Christie Peluso 🧠 @nataliepeluso.com · 23/02/2025
Activation of neurons in the medial amygdala and oxytocin-expressing neurons in the hypothalamic paraventricular nucleus drive the impulse to revive an unconscious companion... An innate drive to save a life | Science #neuroskyence www.science.org/doi/10.1126/...
science.org
An innate drive to save a life
In mice, two brain regions drive the impulse to revive an unconscious companion
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LPJ Lab - Neuroimmunometabolism @lpjlab.org · 20/02/2025
Be part of our groundbreaking science! We're hiring a Project Coordinator to support our research team. Apply now: www.jobs.cam.ac.uk/job/50370/ Please share! #hiring #projectcoordinator #sciencejobs
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Jiri Hofbrucker @deepjdog.bsky.social · 19/02/2025
🚀 We’re Hiring a Photonics Scientists DeepEn develops minimally invasive microendoscopes for neuroscience applications. Using holographic light control, we transform a single optical fiber into a hair-thin imaging device, bringing microscopy into deep brain regions. lnkd.in/ee6VMNaM #ScienceJobs
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Kate Ellacott @neuroendo.bsky.social · 06/02/2025
🚨 Job alert 🚨 We have a 1-year post-doc position available at @exetermed.bsky.social with @craigbeall-lab.bsky.social to study the impact of maternal diet on astrocytes during development. Friendly and inclusive team in a beautiful location. Application deadline 5th March tinyurl.com/3zhd8wsm
media.tenor.com
a drawing of a brain with a rainbow and a blue one
Alt: a drawing of a brain with a rainbow on one hemisphere and blue on the other
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Stephanie Rossit @stephanierossit.bsky.social · 04/02/2025
🧠 📌 FINAL CALL FOR POST-DOC IN NEUROIMAGING 🧠 📌 Do you have (or will have soon) a PhD in Psychology, Neuroscience or Neuroimaging? Are you looking for a post-doc in neuroimaging? Do you want to join a friendly lab in a fab Psychology department? Do you wish to live in gorgeous Norwich?
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