The German Research Foundation (DFG) is funding seven new research groups (FOR) with a total of €33 million. One of these, DFG-FOR 5872, is dedicated to the role of molecular chaperones in the regulat...

Biomolecular condensates are made of multiple components but current techniques cannot capture their complex composition quantitatively. Now it has been shown that the dense-phase binodal point defini...

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Discovery by researchers in Dresden and Edinburgh points to new understanding of the onset of ALS.

»Biomolekulare Kondensate« in unseren Körperzellen organisieren die dortigen Abläufe und bieten neue Ansatzpunkte, um Krankheiten zu behandeln

Biomolecular condensates formed by intrinsically disordered protein condensates are known to be semidilute solutions, however, the molecular interactions in the dilute versus dense phases remain under...

Nixon-Abell et al. show that ANXA11 condensation on lysosomal membranes causes a coupled phase transition of the underlying lipids and mechanical stiffening of the overall ensemble involved in RNP gra...

Cells use membraneless compartments to organize their interiors, and recent research has begun to uncover the molecular principles underlying their as…

Tiny specks called biomolecular condensates are leading to a new understanding of the cell

Biomolecular condensates are non-stochiometric assemblies that organize cellular matter in space and time. Despite much work, many questions remain regarding what determines the recruitment and exclus...