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Cryo Mariena

@cryomariena.bsky.social
845 followers 542 following 235 posts

I like big scopes + I cannot lie. Struct bio + mat sci. Boricua. Pastafarian. Opinions = my own. #cryoeming since 2004. She/Her

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Reposted by Cryo Mariena
WutTheWut😵‍💫 RBroeck🗳️💙 @wutthewut.bsky.social · 29/08/2026
Believe the science. It is literally written in stone. Vaccinate.
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Cryo Mariena @cryomariena.bsky.social · 04/08/2026
If I were you, I'd wish @davidamuller.bsky.social a happy birthday 🎁🎉🥳🎂
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Cryo Mariena @cryomariena.bsky.social · 28/07/2026
Hey look @nozomi-ando.bsky.social
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Cryo Mariena @cryomariena.bsky.social · 10/07/2026
17 years ago, on a day like today, I had my thesis defense. Definitely one of my favorite presentations ever, even though I was so nervous. So many wonderful developments have happened since then.
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Cryo Mariena @cryomariena.bsky.social · 05/07/2026
Today I turned 45 (and my mom turned 77). I spent a quier day at home. Thinking of the craziness this last year has been. The new people I've met, the opportunities I've been given, the good fortune I've had.
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Cryo Mariena @cryomariena.bsky.social · 02/07/2026
Attending the B exam of one of our users. He's used SPA to do reconstructions of Si nanocages. Lots of cool stuff. I'm so proud of our users!!
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David A Muller @davidamuller.bsky.social · 06/06/2026
Seeing Li ions at atomic resolution is hard, seeing the missing ones? Harder. Dasol's electron ptychography now images Li vacancies in a battery cathode in 3D—atom column by atom column: pubs.acs.org/doi/10.1021/... @pubs.acs.org 🧪⚛️
pubs.acs.org
Atomic-Scale Imaging of Lithium Vacancies in a Battery Cathode by Multislice Electron Ptychography
Atomic-resolution imaging of battery materials is critical for identification of local defects and structural variations, which are tied to battery performance. However, since battery materials are, b...
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Cryo Mariena @cryomariena.bsky.social · 24/06/2026
Today, as pretty much every day, I miss you. I miss your wisdom, your character, your sense of justice, equity, fairness. Your fight to balance the scales. I also miss your humor and humanity. I can't believe that in a world full of randomness, I got to cross paths with you. Ich liebe dich.
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DrArchivalGenomics @ehekkala.bsky.social · 24/06/2026
🧪🦠🌏🧬👇
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Cryo Mariena @cryomariena.bsky.social · 06/06/2026
Missing you and all your atoms, especially today. We should've been making you blush by singing happy birthday (very offkey) and eating that delicious fruity cake from Wegmans you liked. Happy birthday to you and Sylvia.
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Jonathan Kaufman @jggkaufman.bsky.social · 18/05/2026
It's finally out! Molecular architecture of mammalian AP3:ARF1 carriers - a mechanism for lysosomal membrane protein trafficking - from a combination of #biochemistry, #cryoET and #cellbiology 📝 Paper: www.science.org/doi/10.1126/... 🧵 Thread: subsequently #teamtomo #membranetrafficking
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 18/05/2026
"Reached for comment by TechCrunch, Musk’s lead counsel Marc Toberoff said, 'One word: Appeal.'" [Two words, actually: "billable hours."]
techcrunch.com
Elon Musk has lost his lawsuit against Sam Altman and OpenAI | TechCrunch
Elon Musk's claim that he was mistreated by his OpenAI cofounders failed after nine California jurors decided in a unanimous verdict that his lawsuits had been filed too late.
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Cryo Mariena @cryomariena.bsky.social · 07/05/2026
FUUUUUUUUUCK. FUCKING FUCK. FUCKING FUCK FUCK. Massive FUCK you to the universe.
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Drug Monkey @drugmonkey.bsky.social · 06/05/2026
When do we start calling him a mass murderer?
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MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 29/04/2026
Congratulations to @lapassmore.bsky.social, Joint Head of the LMB’s Structural Studies Division, who has been elected an international member of @nationalacademies.org Congratulations to #LMBalumni Andrea Brand who has also been elected. Read more: mrclmb.ac.uk/news-events/... #LMBNews
Lori passmore
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Kihara Laboratory @kiharalab.bsky.social · 30/04/2026
We will host a ~30-45 min webinar introducing EM-server for cryo-EM structure modeling on May 6 (Wed) 12:30pm (Eastern Time). Will introduce DAQ-Score plugin & CryoZeta. EM-Server: em.kiharalab.org Registration link: kiharalab-events.vercel.app Hope to see you there!
em.kiharalab.org
EM Server
Kiharalab EM Server
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David A Muller @davidamuller.bsky.social · 12/03/2026
@sciencex.bsky.social ex.bsky.social picked up our #ptychography paper on imaging the atomic-scale roughness in transistor channels in 3D, in a single scan and without having to tilt the sample. ⚛️
ex.bsky.social
Bluesky
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Cornell Center for Materials Research (CCMR) @cornellccmr.bsky.social · 26/03/2026
Atomic‑scale nickel. Zero precious metals. Serious fuel‑cell power—thanks in part to CCMR tools news.cornell.edu/stories/2026...
news.cornell.edu
Nickel catalyst enables high-performance fuel cell free of precious metals | Cornell Chronicle
Cornell researchers have developed a non-precious-metal catalyst that represents a major step toward alkaline fuel cells that use inexpensive commodity metals, such as nickel and cobalt, in several en...
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bioRxiv Molecular Biology @biorxiv-molbio.bsky.social · 22/04/2026
Cryo-FIB lamellae enable ultra-high excitation laser intensities for cryogenic super-resolution fluorescence imaging www.biorxiv.org/content/10.64898/20…
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Cryo Mariena @cryomariena.bsky.social · 22/04/2026
Too cool!
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Edward T Eng @edwardteng.bsky.social · 17/04/2026
Save the date: NYC-ISB26 Integrative Structural Biology symposium - Oct 8-9, 2026 Registration coming soon. Integrative structural biology is a powerful approach toward understanding biological macromolecular systems by bridging structural biology and biophysical methods. nysbc.org/nyc-isb26/
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Cryo Mariena @cryomariena.bsky.social · 21/04/2026
Friends on this side of the pond (US) ... any of you have a K2 Digitizer around you'd be willing to part with? Ideally manufactured from 2016 onwards. If so, feel free to let me know or if you come across @davidamuller.bsky.social somewhere in the world :). Thanks in advance!!
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Cryo Mariena @cryomariena.bsky.social · 15/04/2026
Yue!!!!!! ❤️❤️❤️❤️
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David A Muller @davidamuller.bsky.social · 02/04/2026
The concept that STEM is reciprocal to TEM is easier to explain with a Nion Column
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Cryo Mariena @cryomariena.bsky.social · 02/04/2026
At one point, I even did electron microscopy in vacuum AND in air (we had an airSEM ... RIP).
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Cryo Mariena @cryomariena.bsky.social · 02/04/2026
Ha! just realized that not only and I bilingual in (transmission) electron microscopy (TEM/STEM), I'm also bilingual in TEMperatures (🤣🤣, RT and cryo), AND bilingual in scanning and transmission electron microscopy.
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Sjors Scheres @sjorsscheres.bsky.social · 02/04/2026
Our latest @biorxivpreprint.bsky.social: "Prion-like transmission of human tau strains in the mouse brain" 🥳 With Michel Goedert and Masato Hasegawa. www.biorxiv.org/content/10.6...
biorxiv.org
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Cryo Mariena @cryomariena.bsky.social · 02/04/2026
Now, even though I say funny things about STEM, I gotta tell you, it's is fun to do, beautiful to collect data in, and I love being able to be bilingual in electron microscopy 😝😝 (TEM and STEM).
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Cryo Mariena @cryomariena.bsky.social · 02/04/2026
Things I say when I'm explaining TEM vs STEM: well, you can think of STEM as reciprocal TEM (always makes people lol). And: oh yeah, because STEM folks don't call it beam, they call it probe, and they don't list the whole beam, just the angle, in mrad 😝
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Cryo Mariena @cryomariena.bsky.social · 27/03/2026
Took a little bit of franken-doing, but, I have two used but in very used condition racks in the old dishwasher. Not more rusted racks. There was blood shed (mine, ofc). But, I did it!
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Cryo Mariena @cryomariena.bsky.social · 25/03/2026
Don't get me wrong, I love biology. A lot. But sometimes I wonder, if I had believed in myself enough, if I couldn't cut it as a mechE. Not too long ago, one of our detectors was acting up. One of my colleagues and I decided to take it apart and check things out, see if anything obvious jumped out
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MiTeGen @mitegen.com · 13/03/2026
Hitchhiker's guide to synchrotron and FEL light sources for quantum technology is now available - A listing of network of all Synchrotron Radiation and Free Electron Laser user facilities in Europe - Learn More zurl.co/KKmEi
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Cryo Mariena @cryomariena.bsky.social · 12/03/2026
when you keep old AF emails and can search, find, and share them with your labbies so they can get shizzle moving. I'm like my mom in that sense, except she keeps stuff and I keep messages 🤣
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Cryo Mariena @cryomariena.bsky.social · 28/02/2026
Thing I may have said to @davidamuller.bsky.social today: I didn't lick the board, just did a sniff test. But I did lick the copper. Because when you were trained in bio, you may lick or sniff things out of scientific curiosity 😆
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Cryo Mariena @cryomariena.bsky.social · 27/02/2026
Why have a red light, when your stage can have a blue light?
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Cryo Mariena @cryomariena.bsky.social · 27/02/2026
We have a misbehaving detector which has caused many of my hairs to turn grey. Well, my students know how to troubleshoot said detector. I was today years old when I learned I am known as ... THE NUCLEAR OPTION because I (try) to help said detector behave.
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MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 24/02/2026
Are you a structural biologist pushing the boundaries of molecular science with an ambitious research programme? Join our Structural Studies Division as a tenure-track Group Leader, with core funding, world-leading facilities & enthusiastic colleagues. Apply by 16 MAR www.nature.com/naturecareer...
Job opening for Research Group Leader in Structural Studies at MRC Laboratory of Molecular Biology, focusing on macromolecular structures.
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Lori Passmore @lapassmore.bsky.social · 24/02/2026
The most important #RNA conference of the year with lots of amazing science and a really friendly atmosphere. This year in beautiful Montreal 🇨🇦 ! www2.rnasociety.org
www2.rnasociety.org
RNA Society
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Cryo Mariena @cryomariena.bsky.social · 24/02/2026
When you remember how to troubleshoot you first baby in the silliest of ways. But hey, it worked! Who am I to question my methods? 🤣🤣
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Alexis Rohou @alexisrohou.bsky.social · 24/02/2026
Our department at Genentech is hiring. We're looking for a freshly-minted PhD (0-3 years) protein biochemist / structural biologist to join as a Sr Scientist. A rare opportunity to join our group leader job family at a more junior level than we usually hire.
careers.gene.com
Senior Scientist, Protein Sciences in South San Francisco, California, United States of America | Research & Development at Genentech
Apply for Senior Scientist, Protein Sciences job with Genentech in South San Francisco, California, United States of America. Research & Development at Genentech
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Pilhofer Lab 🦠❄️🔬 @pilhoferlab.bsky.social · 11/02/2026
Contractile Injection Systems - Hot Springs - cryoET: Read the final version of our paper here: academic.oup.com/ismej/advanc... #microsky #teamtomo
academic.oup.com
Thermophilic bacteria employ a contractile injection system in hot spring microbial mats
Abstract. Bacterial contractile injection systems (CISs) are multiprotein complexes that facilitate the bacterial response to environmental factors or inte
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Cryo Mariena @cryomariena.bsky.social · 12/02/2026
Awww. When guests come and bring goodies from our friendly neighbours upstairs. I miss the kindness of Canada. And I absolutely adore how excited they seem to be at the fact that Benito included them in the show.
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Cryo Mariena @cryomariena.bsky.social · 11/02/2026
Half joking. I'm. Toys r Us kid. I don't want to grow up. That, and the fact that the boss and sub-bosses always encourage curiosity and learning to troubleshoot like FSEs.
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Cryo Mariena @cryomariena.bsky.social · 11/02/2026
When you manage to fix an issue for a FSE in a couple of mins, without needing to restart a single thing. And the FSE says: that's very impressive. And I say, when I grow up I want to be like you 😁.
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STEAMLORD @exoplanetdinosaur.bsky.social · 11/02/2026
Happy Women in science day. On this day I am thinking of all my women science mentors and Rita Levi-Montalcini who did experiments in her bedroom in defiance of Mussolini’s ban on Jews in academic and professional careers while WWII raged around her.
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Cryo Mariena @cryomariena.bsky.social · 11/02/2026
About the only thing I feel like celebrating right now (well, along with doing a semi flawless cryo insertion)
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Cryo Mariena @cryomariena.bsky.social · 11/02/2026
Many congrats to our fearless leader @davidamuller.bsky.social www.nae.edu/19579/31222/...
nae.edu
National Academy of Engineering Elects 130 Members and 28 International Members
The National Academy of Engineering (NAE) today announced the election of 130 members and 28 international members to its Class of 2026, said NAE President ...
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Cryo Mariena @cryomariena.bsky.social · 10/02/2026
I still got it. Doing a cryo insertion for the first time this year and it went beautifully. 22yrs and it's still there *chef's kiss.*
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RCSB Protein Data Bank @rcsbpdb.bsky.social · 10/02/2026
Use RCSB PDB's Pairwise Structure Alignment tool to compare existing PDB structures or Computed Structure Models (or upload a local file) #LoveDataWeek www.rcsb.org/alignment
"Let's align our coordinates" valentine with Oxytocin receptor ("love hormone") aligned with vasopressin receptor
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Cynthia Pelayo @cynthiapelayo.bsky.social · 09/02/2026
For those unaware about the significance of the light poles during the song El Apagón it’s because of the Puerto Rican power system and the constant black outs. There have been a lot of protests on the island over this.
Bad Bunny in a field
Light poles behind him
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