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Clément Hallopeau

@challopeau.bsky.social
116 followers 179 following 0 posts

Mechanics, tissue dynamics, all kinds of biophysics In @XavierTrepat lab at @IBECbarcelona.

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Reposted by Clément Hallopeau
Ricard Solé @ricardsole.bsky.social · 16/08/2026
Can AI discover General Relativity? No, not yet. A provocative new paper argues that LLMs can master induction and deduction, but not the crucial abductive “jump” that allows us to invent entirely new principles. A fascinating question about the limits of AI openreview.net/challenge?re...
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Carlos Pérez-González @cperez-gonzalez.bsky.social · 18/02/2026
I’m thrilled to share that I will join @gustaveroussy.fr as a Group Leader! Our objective: to understand how mechanochemical feedbacks regulate tumor dynamics and plasticity, with the overarching goal of bridging tissue mechanobiology and tumor pathophysiology using human organoids.
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Nimesh Chahare @onenimesa.bsky.social · 23/10/2025
Join the coolest club on the internet! #EpithelialMechanics
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Reposted by Clément Hallopeau
Julia Eckert @juliaeckert.bsky.social · 23/10/2025
Exciting News! 🥳 Our Epithelial Mechanics Fan Club website is now live! 🎉 👉 epithelialmechanics.github.io Discover our #EpithelialMechanics threads and get to know our amazing delegates behind them. Would you like to share your story? Please DM us!
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Carlos Pérez-González @cperez-gonzalez.bsky.social · 16/10/2025
1/ 🎉Excited to share our new preprint @vignjeviclab.bsky.social @davidbrueckner.bsky.social : "Self-organization of tumor heterogeneity and plasticity" biorxiv.org/content/10.1... Tumor heterogeneity and plasticity drive metastasis and relapse. How is tumor patterning coordinated? A thread👇
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Levayer Lab @levayerr.bsky.social · 15/09/2025
Epithelial crowding drives membrane depolarisation by ENaC/Na+ entry which triggers rapid volume loss, piezo activation and live cell extrusion. Importantly, low intracellular ATP primes cells for live extrusion by preventing the restoring of mb polarisation. www.nature.com/articles/s41...
nature.com
Energy deficiency selects crowded live epithelial cells for extrusion - Nature
Crowded epithelial cells with the least energy and membrane potential are selected for extrusion.
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paveltomancak.bsky.social @paveltomancak.bsky.social · 04/09/2025
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
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Pau Guillamat @pauguillamat.bsky.social · 30/06/2025
New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations. The tissue morphogenesis logic, now engineered into living, programmable materials. www.biorxiv.org/content/10.1... #ActiveMatter #TissueEngineering
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Camilla Autorino @cami-autorino.bsky.social · 11/06/2025
🔔 Proud to share the preprint of my PhD work in the Petridou group @nicolettapetridou.bsky.social @embl.org ✨ “A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics” 🐟 🔁 📶 🔗 www.biorxiv.org/content/10.1... #devbio #biophysics 🧵⤵️
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Levayer Lab @levayerr.bsky.social · 21/05/2025
Many cells during development are exposed to caspase activation and yet survive. Why some die and not others ? We found out that the memory of previous caspase activation bias significantly later death comitment and bias death distribution and single cell decision www.biorxiv.org/content/10.1...
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Denis Krndija @deniskrndija.bsky.social · 06/04/2025
🥳 Thrilled to share our lab's first preprint, led by our talented postdoc Justine Creff! 👩🏻‍🔬 We tackled a fundamental question: how the epithelium withstands mechanical stress at the interface of cells with distinct geometries and mechanics, such as enterocytes (E) and goblet cells (G) (1/9)
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Alice Perucca @aliperri.bsky.social · 10/02/2025
1/7: New paper alert! Excited to share our co-first author paper on Micro Immune Response On-chip (MIRO) a model that recreates the tumour-stroma interface for immunotherapy testing! @oriolmb.bsky.social and I wrote this thread to break it down for you. 👇🧵 Read more: www.nature.com/articles/s41...
nature.com
Micro Immune Response On-chip (MIRO) models the tumour-stroma interface for immunotherapy testing - Nature Communications
Modelling the tumour immune microenvironment in vitro is a valuable tool to test immunotherapy efficiency but capturing its complexity is challenging. Here authors present a fully humanised in vitro p...
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Levayer Lab @levayerr.bsky.social · 13/01/2025
How oncogenic clones can eliminate their neighbours to take over space ? There are different ways combining growth and interfacial tension induced compaction. Check out our latest preprint led by Léo Valon and Alexis Matamoro-Vidal to learn more about this 👇 www.biorxiv.org/content/10.1...
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