Nature - Models of how the brain changes over time could help researchers to understand how diseases affect the organ later in life.

In this review, we detail the features of barrier germinal centers (GC) that form in tertiary lymphoid structures (TLSs) within non-immune organs that…

New York, NY (Onsite)

Join us at the Keystone Symposia on B Cells and Plasma Cells: Fundamental and Translational Biology, March 2026, in Keystone, with field leaders!

IgA plasma cells are the most abundant antibody-secreting reservoir in the body, yet details of their origin and behavior remain elusive. In this issue of Immunity, Simons et al. and Siniscalco et al....

Three recent papers quantify how nucleotide-level mutation processes drive antibody evolution.

United States Senate Committee on Appropriations

Washington, D.C. – Today, U.S. Senator Patty Murray (D-WA), Vice Chair of the Senate Appropriations Committee, issued the following statement on reports today that President Trump’s Office of Manageme...

Researchers like Richard Huganir are closing in on a cure for SYNGAP1-related disorders. But in the face of federal funding cuts, can they finish what they started?

From 2020 to 2024, universities contributed patents underpinning 50% of FDA-approved drugs. 87% of those academic breakthroughs came from American institutions.

Widespread dissatisfaction over the NIH’s “continuous free fall” has people speaking out.

Five recent papers identify the RORγt+ antigen-presenting cells that induce food-antigen-specific regulatory T cells and establish food tolerance.

Immune responses lie at the heart of almost every aspect of human health, including host responses to infection, autoimmunity, cancer, metabolism and aging. While adaptive immune responses by B and T…

Shruti Naik, an immunologist and a strong advocate for diversity in science, has joined forces with Aaron Mertz, who leads programmes that help to explain, connect and maximize the benefits of science...

Initial specificity is thought to be required for somatic hypermutation (SHM)-driven antibody evolution. Zuo, Gautam, et al. demonstrate that non-cognate B cells can enter germinal centers, undergo SHM, and acquire new antigen specificities, highlighting the capacity of antibodies to generate new recognition through SHM.