Intra-tumour heterogeneity (ITH) and cellular plasticity contribute to therapy resistance. Single-cell transcriptomics is the gold standard for assessing ITH, but this approach remains costly and slow...

OverviewLymph node (LN) metastasis is a hallmark of disease progression in most solid tumors and remains one of the most consistent predictors of poor prognosis and reduced overall survival. In partic...

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Cuts and layoffs to the National Institutes of Health threaten medical research around the U.S., agency insiders warn.

TO THE AMERICAN PEOPLE We all rely on science. Science gave us the smartphones in our pockets, the navigation systems in our cars, and life-saving medical care. We count on engineers when we drive acr...

On Monday, January 27th, 2025, President Trump issued an order to freeze virtually all of approved and legally required federal funding.

NIH officials said they were given no advance warning and less than an hour to post the memo publicly.

NIH-related updates to the Federal Register, which are required for the scheduling of study sections and advisory councils, are on hold indefinitely, according to an email reviewed by <i>The Transmitt...

In 1964, the Declaration of Helsinki created a set of universal ethical principles to protect human participants in health research.1 Described as “the cornerstone of research ethics,”2 these principl...

YouTube video by Association of American Universities

Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068)

Select a state on the map to see the impact of NIH funding across America.

Join us at the Keystone Symposia on T Cell Differentiation in Tissue Microenvironments, February 2025, in Vancouver, with field leaders!

Researchers facing

A lot of talent is wasted in a world where more than half of laureates come from households in the richest 5%

Lymphatic vessels play a crucial role in activating anti-tumor immune surveillance but also contribute to metastasis and systemic tumor progression. Whether distinct lymphatic phenotypes exist that go...

Liver X receptor drives epithelial Areg-mediated intestinal regeneration, while preventing tumour growth through adaptive immune responses.