New experiments identify a receptor that helps regenerate the brain’s white matter after #stroke—and reveal that activating this receptor enhances cognitive and motor recovery in mice by stimulating “clean up” cells called microglia. #ScienceSignaling scim.ag/456KI3v
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Adenosine 2A receptor drives microglial efferocytosis to accelerate white matter repair and functional recovery after stroke
Stimulating the efferocytosis of cellular and myelin debris by microglia after stroke promotes remyelination.