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Antonia Sagona

@antoniasagona.bsky.social
303 followers 296 following 15 posts

Reader (Associate Professor) in School of Life Sciences, University of Warwick, UK. Interested in bacteriophages and phage therapy.

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Reposted by Antonia Sagona
Tamas Lazar @tamaslazar.bsky.social · 01/09/2026
International postdocs are welcomed to apply for interdisciplinary research positions as #MSCA fellows @vubrussel.bsky.social. If you are interested in computational protein science, contact me in email for supervision. Or find other Life Sci. supervisors here: interact-programme.be/vub-supervis...
interact-programme.be
VUB supervisors
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Willem van Schaik @wvschaik.bsky.social · 20/09/2026
Brilliant paper by the labs of @epcrocha.bsky.social @jrpenades.bsky.social 'Mobile genetic elements drive a plasmid fusion and deletion lifecycle shaping evolution and antimicrobial resistance' www.nature.com/articles/s41...
nature.com
Mobile genetic elements drive a plasmid fusion and deletion lifecycle shaping evolution and antimicrobial resistance - Nature Communications
Plasmids drive bacterial adaptation, but how their diversity arises has remained unclear. Here, they show that in Staphylococcus aureus, mobile genetic elements repeatedly fuse and delete plasmids, re...
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Rafal Mostowy @rafalmostowy.bsky.social · 04/09/2026
🧬 Postdoc ad is now live: evolutionary genomics of Klebsiella pneumoniae phages. How do prophage depolymerases vs SGNH-esterases shape phage host range? Krakow, Poland. Deadline 21 Sept: mostowylab.com/job-postdoc-...
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Patrick Moynihan @pmoyniha.bsky.social · 24/06/2026
New paper in collaboration with @proftracypalmer.bsky.social, @lislowe.bsky.social and many more. We show that mycobacteria produce Type VII secreted anti-bacterial protein toxins. Excited to explore this new area of mycobacterial biology. www.nature.com/articles/s41...
nature.com
A Type VII-secreted toxin enables inter-mycobacterial competition - Nature Communications
Mycobacteria have not yet been reported to engage in interbacterial competition via secretion of proteinaceous toxins. Here, Benedict et al. show that some mycobacteria can use their type-VII secretio...
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Tracy Palmer @proftracypalmer.bsky.social · 24/06/2026
Check out our latest T7SS toxin story. These reverse toxins aren’t as rare as we thought!
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Paul Turner Lab @paulturnerlab.bsky.social · 06/06/2026
Come see my former postdoc @cathyhernandez.bsky.social’s presentation on how prophages shape thermal performance in marine bacteria (room 147AB at 12:15PM). Cathy is now a professor at the University of South Carolina and is recruiting PhD students for Fall 2027!
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Vivek Mutalik @vivekmutalik.bsky.social · 19/05/2026
Revised story Systematic receptor mapping in acapsular Klebsiella www.biorxiv.org/content/10.6...
biorxiv.org
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Britt Koskella @bkoskella.bsky.social · 19/05/2026
Please share widely! Abstract submissions open for the 2026 Jacques Monod conference: Ecology and evolution of host-parasite interactions in a changing world! Held in beautiful Roscoff France from November 2- 6, 2026. Abstracts submission deadline : June 6 cjm.sb-roscoff.fr/en/conferenc...
cjm.sb-roscoff.fr
Ecology and evolution of host-parasite interactions in a changing world | CNRS - Conférences Jacques Monod (CJM)
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Franklin Nobrega @fnobrega.bsky.social · 14/05/2026
Very happy to share our Druantia III–Zorya II synergy story, now on bioRxiv: www.biorxiv.org/cgi/content/short/2026.05.12.724681v1 It appears alongside several Druantia III papers from excellent colleagues, each telling a different part of the story. (links below)
biorxiv.org
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Vivek Mutalik @vivekmutalik.bsky.social · 13/05/2026
Bacterial−viral conflicts shape cholera evolution www.nature.com/articles/d41... #phagesky #microsky
nature.com
Bacterial−viral conflicts shape cholera evolution
Genomics and experimental data suggest that an evolutionary arms race between cholera-causing bacteria and their viral predators shapes the disease in humans.
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Michael Brockhurst @brockhurstlab.bsky.social · 08/05/2026
Less than 1 week to apply for this postdoc! If you want to find out more about the project have a look at our recent preprint: www.biorxiv.org/content/10.6... #mevosky
biorxiv.org
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Michael Brockhurst @brockhurstlab.bsky.social · 28/04/2026
We have a PhD studentship available to develop genome safeguarding technologies for synthetic phage therapeutics www.findaphd.com/phds/project... It is part of an exciting new @officialuom.bsky.social PhD by Enterprise programme www.bmh.manchester.ac.uk/study/resear...
findaphd.com
(PhD by Enterprise) Genome safeguarding technologies for synthetic phage therapeutics against multidrug resistant bacterial infections at The University of Manchester on FindAPhD.com
PhD Project - (PhD by Enterprise) Genome safeguarding technologies for synthetic phage therapeutics against multidrug resistant bacterial infections at The University of Manchester, listed on FindAPhD...
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Simon Roux @simrouxvirus.bsky.social · 24/04/2026
www.nature.com/articles/s41...
nature.com
Phage host range: determinants, dynamics and applications - Nature Reviews Microbiology
Comprehensive assessment of the host range of phages is a prerequisite for their safe and effective use in multiple applications but is rarely undertaken. This Review outlines the molecular and ecolog...
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Tim Overton @overtonlab.bsky.social · 24/04/2026
New paper! We have written a (hopefully) simple primer on microbial energy metabolism - how do bacteria harvest energy from their environment, and how does this impact their behaviour? www.microbiologyresearch.org/content/jour...
microbiologyresearch.org
Microbial Primer: Bacterial energy metabolism
All cells need energy to perform their functions. This primer introduces energy metabolism in bacteria, with a focus on key pathways and examples from model organisms, while acknowledging that bacteri...
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davidroper2.bsky.social @davidroper2.bsky.social · 21/04/2026
Congrats to Charis Thompson in my lab and joint student with @friendlymicrobe.bsky.social who has just won the 2026 Dr Mrytle Pridgeon Scholarship! @warwicklifesci.bsky.social
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Jessica Blair @jessicamablair.bsky.social · 21/04/2026
Applications are officially OPEN for the 2027 Gordon Research Conference on Multidrug Efflux Systems. 📅 When: March 21–26, 2027 📍 Where: Ventura, California 🔗 Apply here: www.grc.org/multi-drug-e... #GRC #MultidrugEfflux
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annadragos.bsky.social @annadragos.bsky.social · 20/04/2026
Our latest work by PhD student Maja Popović in collab with @romain-briandet.bsky.social & Yasmine Dergham=> Disruption of bacteriophage integration site promotes rapid diversification of multicellular traits in Bacillus subtilis | Microbiology Spectrum journals.asm.org/eprint/MQ2RH...
journals.asm.org
Disruption of bacteriophage integration site promotes rapid diversification of multicellular traits in Bacillus subtilis | Microbiology Spectrum
Prophages, defined as viruses integrated into bacterial genomes, can reshape bacterial physiology and evolution. Previous studies suggested that disruption of an integration site (spsM) by the SPβ pro...
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Vivek Mutalik @vivekmutalik.bsky.social · 19/04/2026
www.nature.com/articles/s41... #microsky
nature.com
Synthetic microbial co-cultures for modular bioelectronic sensing in diverse environments - Nature Biotechnology
Modular integration of bacterial strains expands the application range of whole-cell bioelectric sensors.
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Ben Adler @benadler.bsky.social · 04/04/2026
10 years ago @vivekmutalik.bsky.social introduced me to the wild world of phages. Today, @lucasmoriniere.bsky.social presents a truly foundational scale bridging genomes, viruses, editing and function. Truly an amazing scale and vision for the future! Congrats to phage foundry 🌶️🌶️🌶️
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Paul Turner Lab @paulturnerlab.bsky.social · 04/04/2026
Our perspective on measuring individual virus traits, led by staff scientist @antanij.bsky.social #phagesky #microsky
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The Gold Lab @the-gold-lab.bsky.social · 01/04/2026
It's been a long road, but thank you to everyone involved in getting this work published! @alexanderneuhaus.bsky.social and @mathewmclaren.bsky.social
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The Gold Lab @the-gold-lab.bsky.social · 02/04/2026
Are you interested in phages, cryoEM, and looking for a PhD opportunity near the beach? www.exeter.ac.uk/research/ins...
exeter.ac.uk
LSI PhD programme | Living Systems Institute | University of Exeter
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Will Smith @willpjsmith.bsky.social · 20/03/2026
Here’s the latest preprint from my work on evolved resistance to Type VI Secretion system (T6SS) weaponry, funded by a @wellcometrust.bsky.social Sir Henry Wellcome Fellowship. So happy to see this out! www.biorxiv.org/content/10.6...
biorxiv.org
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Vivek Mutalik @vivekmutalik.bsky.social · 26/03/2026
www.pnas.org/doi/10.1073/... Phages drive the dissemination of antibiotic resistance genes by facilitating host adaptation to heavy metal stress #phage #phagesky
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Alexander Harms @aharms485.bsky.social · 07/03/2026
New preprint of our friend Aritz Roa @aritz-roa.bsky.social with Nicholas Taylor @nmitaylorlab.bsky.social - even if phage mechanics are not your thing, check out their MAGNIFICENT video of T4 host recognition + infection directly im the post! 🎬🧬🔥
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Franklin Nobrega @fnobrega.bsky.social · 03/03/2026
Have a read! www.biorxiv.org/content/10.6...
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Franklin Nobrega @fnobrega.bsky.social · 03/03/2026
In our latest work, we characterise the Tmn defence system. We reveal plasmolysis as a new way to block phage infection, dramatically reducing secondary infections.
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Peter Fineran @peterfineran.bsky.social · 04/03/2026
Appl here : apc01.safelinks.protection.outlook.com?url=https%3A...
apc01.safelinks.protection.outlook.com
Postdoctoral Fellow - Microbiology and Immunology
Click the link provided to see the complete job description.
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Peter Fineran @peterfineran.bsky.social · 04/03/2026
New post-doctoral research position in my phage-host interactions (Phi) laboratory in @otagomicroimmuno.bsky.social at @universityofotago.bsky.social New Zealand. The project is focused on defences against jumbo phages. Please share and if interested apply using the link in the comments.
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BejaLabTechnion @bejalab.bsky.social · 25/02/2026
Convergent MurJ flippase inhibition by phage lysis proteins www.nature.com/articles/s41...
nature.com
Convergent MurJ flippase inhibition by phage lysis proteins - Nature
A common mechanism of inhibition of the essential lipid II flippase MurJ by three distinct phage-encoded single-gene lysis proteins provides insights into potential new targets for antimicrobial devel...
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Waggoner Lab @labwaggoner.bsky.social · 26/02/2026
SNIPE is a widespread bacterial defence system that exploits the spatial organization of phage genome injection to specifically target viral DNA, distinguishing self from non-self in prokaryotic immune systems @nature.com @mitpress.bsky.social www.nature.com/articles/s41...
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Rafal Mostowy @rafalmostowy.bsky.social · 26/02/2026
📢 Hiring a Postdoc in Computational Phage Biology (Kraków, Poland) We study the evolution & structural modularity of prophage-encoded glycan-degrading enzymes in Klebsiella pneumoniae — combining genomics and AlphaFold-based analyses. Details in attached PDF 👇
docs.google.com
Postdoc Ad
Postdoctoral Position in Computational Phage Biology Microbial Genomics Group, Malopolska Centre of Biotechnology (MCB), Jagiellonian University, Kraków PL Summary We are seeking a postdoctoral rese...
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Michael Brockhurst @brockhurstlab.bsky.social · 14/02/2026
What’s holding back clinical use of phage therapy in the UK? Our workshop last year brought together international experts, biotech and regulators to find out Meeting Report out now in Nature Microbiology with our take on the challenges and opportunities facing the UK phage therapy sector
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Michael Brockhurst @brockhurstlab.bsky.social · 20/02/2026
How does treatment induced antibiotic resistance happen in real-world infections? We analysed 25k Pseudomonas isolates from 180 patients in a clinical trial to find out! TLDR: The ecological and evolutionary paths are surprisingly diverse & complex even in patients receiving identical treatment…
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Jyot Antani @antanij.bsky.social · 24/02/2026
Yet another awesome single-phage paper from Ido Golding's lab #phagesky www.biorxiv.org/content/10.6...
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Michael Brockhurst @brockhurstlab.bsky.social · 06/02/2026
Exciting new PhD programme CODE-M Control and Design of Engineered Microbial Systems @officialuom.bsky.social Projects now advertised! Ours is on division of labour & horizontal gene transfer in microbial communities @biotechdixon.bsky.social @coytelab.bsky.social www.findaphd.com/phds/project...
findaphd.com
(CODE M) How do Division of Labour and Gene Mobility Impact Microbial Bioremediation? at The University of Manchester on FindAPhD.com
PhD Project - (CODE M) How do Division of Labour and Gene Mobility Impact Microbial Bioremediation? at The University of Manchester, listed on FindAPhD.com
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Michael Brockhurst @brockhurstlab.bsky.social · 06/02/2026
New PDRA position with @knightjar.bsky.social @coytelab.bsky.social & me Community assembly processes in soil microbiomes with focus on bioinformatics and computational modelling of data from field and lab experiments www.jobs.manchester.ac.uk/Job/JobDetai...
jobs.manchester.ac.uk
'Research Associate in Microbiome Ecology:Manchester
We wish to appoint a PostDoctoral Research Associate to an exciting project exploring the assembly, stability and function of microbial decomposer communities.
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Emmanuele Severi @emmseveri.bsky.social · 23/01/2026
#microsky #phagesky #phage defence www.nature.com/articles/s41...
nature.com
A bacterial defense system targeting modified cytosine of phage genomic DNA - Nature Communications
In this study, the authors identify and structurally characterize a single-component anti-phage defense system named CMoRE (Cytosine Modification Restriction Endonuclease).
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Sabrina Green @motherofphage.bsky.social · 14/01/2026
I think the #phages are spelling something. Phage + bacterial droplets as a way to quantify infectious titer. This is work from Stefan Vermeulen from HO Gent. This is a salmonella phage infecting after 180 minutes. The PMD4U platform with patented methodology.
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Aude Bernheim @audeber.bsky.social · 15/12/2025
Bacterial genomes encode a rich repertoire of antiphage systems, but we still know surprisingly little about when these systems are actually expressed. In this preprint, Lucas Paoli et al, ask what shapes antiphage systems expression in native contexts. www.biorxiv.org/content/10.6...
biorxiv.org
Environment and physiology shape antiphage system expression
Bacteria and archaea encode on average ten antiphage systems. Quorum sensing, cellular, or transcription factors can regulate specific systems (CRISPR-Cas, CBASS). Yet, a systematic assessment of anti...
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Jessica Blair @jessicamablair.bsky.social · 18/11/2025
Really excited to say that we have been awarded a BBSRC sLola! Really looking forward to kick off this project with such a fantastic team! @webberma.bsky.social @overtonlab.bsky.social @bugsinblood.bsky.social Sara Jabbari, Dong-Hyun Kim @imibirmingham.bsky.social www.ukri.org/news/powerin...
ukri.org
Powering team science to unlock life’s secrets
Four world-class teams awarded major BBSRC sLoLa grants to push the frontiers of discovery in microbiology, photosynthesis, gene regulation and quantum biology.
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Emmanuele Severi @emmseveri.bsky.social · 16/11/2025
Interesting CRISPRi screening in Smeg to identify factors modulating resistance to antimicrobials (new insights into the role of the cell envelope)
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Antonia Sagona @antoniasagona.bsky.social · 14/11/2025
Many congratulations one more time for an excellent viva! @tosinorababa.bsky.social Fantastic work!!
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Chris Corre @correlab.bsky.social · 28/10/2025
Very happy to have been involved in the discovery of “pre-methylenomycin C lactone”, a promising new antibiotic from Streptomyces bacteria - #JACS warwick.ac.uk/news/pressre...
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Freya Harrison @friendlymicrobe.bsky.social · 13/11/2025
#PhDone! Congratulations to Dr @tosinorababa.bsky.social, who passed his viva today 🎉
A group of people at a restaurant table
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Alexander Harms @aharms485.bsky.social · 13/11/2025
Fantastic paper by James Bean and colleagues on phage Bas63 - this has been one of the first phages I ever isolated just for fun as a PhD student (in 2012!). It's #2 on this plate of Rhine river water on an E.coli K-12 lawn.... How it started /// How it's going
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Emmanuele Severi @emmseveri.bsky.social · 03/11/2025
#microsky #phagesky #phage defence Novel bacterial ubiquitination-like pathway! www.nature.com/articles/s41...
nature.com
Mechanistic basis for protein conjugation in a diverged bacterial ubiquitination pathway - Nature Structural & Molecular Biology
Ye et al. define the structure and mechanisms of a bacterial pathway that performs ubiquitination-like protein conjugation, revealing new insights into the evolution and biological roles of ubiquitina...
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Syma Khalid @sykhalid.bsky.social · 02/11/2025
Really interesting interview. @timcoulson.bsky.social and I were also fortunate to chat with David Baker on our podcast which you can catch here: Science Of The Times EP7 Pt2 - Interview with 2024 Nobel Prize winner for Chemistry David Baker youtu.be/jShxgJ3XrWA
youtu.be
Science Of The Times EP7 Pt2 - Interview with 2024 Nobel Prize winner for Chemistry David Baker
YouTube video by Science Of The Times Podcast
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Asaf Levy @asaflevylab.bsky.social · 26/10/2025
R.I.P Hamilton Smith, 1978 Nobel Laureate for the discovery of type II restriction-modification systems (HindII).
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Ellie Jameson @elliejameson.bsky.social · 26/10/2025
Day 26, Give. This virus of bacteriophage Zamilon virophage, might benefit the bacteria (or not). Virophage infect viruses, in particular the giant DNA virus family Mimiviridae. #Drawtober #PhageSky #SciArt
Black and white ink drawing of a hexagonal viral particle with a faint, pale 5-point star shaded with stippling.
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