The common antibiotic doxycycline inhibits the ribosome. Here, using cryo-EM, the authors identify additional binding sites for doxycycline in the Coxiella burnetii and E. coli ribosomes.

Outnumbering their hosts by at least a factor of 10, viruses are the most common biological entity on Earth, are major drivers of evolution, and greatly impact on the dynamics of our planet's ecosyste...