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Span

@anna2.bsky.social
34 followers 357 following 182 posts

spanning with spandrels whiles tnetting on 'kneedles

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sarah boothby @swastrosarah.bsky.social · 09/10/2026
Justice4me.uk lawyers have asked me for evidence of my submissions to DHSC and NHS England 2022 - ongoing. I have obliged; why would I not? What Maeve and I went through has not stopped, despite a 3 year inquest and 6 national institutions being cited in the Prevention of Future Deaths report 2024.
justice4me.uk
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J. Offir, PhD @joffirphd.bsky.social · 29/09/2026
in the development of autoimmune conditions like lupus & multiple sclerosis, and chronic ME/CFS, as well as cancers. Folks wanting to know about EBV vax research can look here: pmc.ncbi.nlm.nih.gov/articles/PMC... and: www.nature.com/articles/s41...
pmc.ncbi.nlm.nih.gov
The case for an Epstein–Barr virus vaccine: Lessons from its link to systemic lupus erythematosus
Growing evidence has strengthened the longstanding hypothesis that Epstein–Barr virus (EBV) contributes directly to the development of systemic lupus erythematosus (SLE). While earlier work establishe...
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brandon-beaber.bsky.social @brandon-beaber.bsky.social · 29/09/2026
Yes: Sunlight, vitamin D, diet, age at EBV infection, hygeine, rate of diagnosis.
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Chris Ponting @cgatist.bsky.social · 28/09/2026
Matthias Wielscher (Vienna) showing significant genetic associations to ME/CFS via rare gene disruptive variants in UK Biobank to C2orf66 and OBSCN genes. Wishes to use long read Oxford Nanopore Technologies approach in a replication study.
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Span @anna2.bsky.social · 25/09/2026
I wonder where dopamine disorder “encephalitis lethargica” and other virus-triggered complications sit in the ranking. “Experience”? life history, known as “age”and stage?
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Anna Wood @annakwood.bsky.social · 25/09/2026
#DVparty #NF RAISING HARE X BODY WEATHER Excited to present my mood board for THE CALL OF THE DUNNOCK, a nature memoir about discovering the wildlife in my suburban garden while grappling with being housebound due to a chronic illness. #mecfs
A montage of 9 photos, 8 showing birds, the centre one is myself a white woman sitting in a wheelchair holding a camera to my face
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Span @anna2.bsky.social · 20/09/2026
Oh this is so good. Adore this game thank you thank you. Anthropeum.com · Sep 21 2026 🟥🟨🟩🟦🟥🟥🟩🟨🟨🟨 50,764 · top 52% of players today!
anthropeum.com
Anthropeum
A daily game that challenges our understanding of human cultures. Ten objects. 5,000 years of human history. Guess where and when each artifact was made. See how you rank.
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Span @anna2.bsky.social · 18/09/2026
Spotting Extinction Debt in the wild (including Aotearoa based research) Thanks for introducing me to this term @endofthepier.bsky.social @xriskology.bsky.social concept might interest
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David Daniel @daviddaniel.bsky.social · 13/09/2026
I was excitedly telling a friend about finally getting Inventing The Renaissance, and explaining who @adapalmer.bsky.social was... which led to me reading her magnificent disability essay for at least the third time. It's where I first learned of Ada's work (and that of @bluejo.eurosky.social).
strangehorizons.com
Writing/Realizing Disability + Power
I chose the photo where I’m with Dad outside the Hugo Losers Party, with my bright blue jacket and my squidgy-handled cane—Dad’s injured hand is in his pocket, not visible, but I know.  So there it…
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A Jean Stevenson @amandajean.bsky.social · 14/09/2026
Why are all those tech dudes so especially weird about fertility rates? It's not just misogyny or eugenics or greed. Their twisted definition of "human" and their odd conceptions of types of extinction and their fundamentally not human goals for the future are all part of the weird story.
realtimetechpocalypse.com
The ASI Extinction Debate Is the Opposite of What You Think
The media needs to wake up, fast. (3,100 words.)
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Leslie Root @lesja.bsky.social · 08/09/2026
OK but consider: what if, by not messing with people's reproductive lives, we are ensuring the defeat of humanity by a giant space meteor. Really makes you think.
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Span @anna2.bsky.social · 06/09/2026
immersive and compulsive listen from @legroff.bsky.social “the hummingbird with its invisible wings, darting among the flowers” 👀 awww not in Engleterre, hummingbird moth perhaps ok, ok, back in 🎧
Matrix by Lauren Groff penguin audiobook, medieval illustrated nuns in twining gilded foliage
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Span @anna2.bsky.social · 01/09/2026
Everything Treatment, for Everything Disease. School refusal & withdrawal w/mixed state, POTS, pain, anxiety, IBS, post partum insomnia, low milk supply, PMDD, migraine disorder, inattentiveness, dysphoria, perimeno Have trialled dozens of prescriptions, of those offered. Teens through 40s
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Steve Fifield @stevefifield.bsky.social · 23/08/2026
So true Emily. Pacing is framed as a means to adjust our approaches & behaviours to maximise capacity & capability. But it's just elimination. You write down a list of activities needed to get you between waking each day -> sleeping, then mark each down, one by one, as unachievable without support.
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Paper Skygest Team @paper-feed.bsky.social · 19/08/2025
**Please repost** If you're enjoying Paper Skygest -- our personalized feed of academic content on Bluesky -- we'd appreciate you reposting this! We’ve found that the most effective way for us to reach new users and communities is through users sharing it with their network
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Tom Kindlon @tomkindlon.bsky.social · 03/08/2026
2/ "we identified 26 genetic risk loci for fibromyalgia, providing robust characterization of its genetic architecture. These findings establish a firm biological basis for a long-debated condition." #Fibromyalgia #Fibro #FMS #FM
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Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · 27/07/2026
Most HPV16 research treats the virus as genetically static. It is not. HPV16 isolates differ by up to ~2% of its ~7900 bp genome, and can differ in cervical cancer risk by >100-fold. We analyzed 4704 carefully-curated HPV16 genomes to study this variability. 2/9
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Libby Heeren @libbyheeren.bsky.social · 24/07/2026
It's never in my entire life worked 😂 For decades, docs told my parents & me, "it's anxiety, she has panic attacks" In my 30s: got an x-ray of my heart. Radiologist wrote "her heart is fine, but why does she have COPD lungs??" Saw a pulmonologist. Raging lifelong asthma. Lungs 150% normal size 🫠
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A Jean Stevenson @amandajean.bsky.social · 20/07/2026
truly the problem is the idea that you can and should maximize utility from other people's reproduction.
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Patrick Deelen @patrickdeelen.bsky.social · 17/12/2025
Great paper. Can we then also conclude that rare recessive diseases would have been more common, where it not for the negative effects that are exerted on carriers?
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Cat Bohannon @catbohannon.bsky.social · 20/06/2026
Not the NYT literally claiming the decline in teen births is an apocalypse *and* that it’s because of phones and not an active international campaign to f’ing reduce teen births as a Moral Good www.nytimes.com/2026/06/18/o...
nytimes.com
Opinion | Why We Delude Ourselves About the Birthrate
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Span @anna2.bsky.social · 19/06/2026
You might enjoy “Shakespeare is Hard, but so is Life” by Fintan O’Toole, a short book. It also includes some asides about Renaissance period in surprising consonance with Palmer.
book.it
book.it - book Resources and Information.
book.it is your first and best source for information about book. Here you will also find topics relating to issues of general interest. We hope you find what you are looking for!
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Lara Durgavich @ldurgavich.bsky.social · 03/06/2026
Fun fact: Mendel originally planned to breed mice but the abbot at his monastery took offense at the idea of a priest having anything to do with sex, so Mendel switched to peas. Mendel was grateful that "the bishop did not understand that plants also have sex.”
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This Podcast Will Kill You @tpwky.bsky.social · 02/06/2026
An accurate diagnosis can give us so much, yet many people wait years to receive an accurate diagnosis, causing a physical and emotional toll. What underlies this and what can we do about it? In this week’s TPWKY book club, Alexandra Sifferlin joins to discuss her book The Elusive Body. Listen now!
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Prof Danny Altmann @daltmann.bsky.social · 28/05/2026
Hard-to-detect mutations explain how common autoimmune diseases arise www.nature.com/articles/d41...
nature.com
Hard-to-detect mutations explain how common autoimmune diseases arise
An old theory gains fresh support from advanced DNA sequencing, which can detect rare mutations in B cells from people with autoimmune thyroid conditions.
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Henry Gee 亨利·纪 @endofthepier.bsky.social · 28/05/2026
‘The Wonder of Life on Earth’, illustrations by Raxenne Maniquiz, published by @twohootsbooks.bsky.social
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Elizabeth Wrigley-Field @wrigleyfield.bsky.social · 18/05/2026
Finally, here's an absolute banger of an article, published just last month (Hoffman et al. 2026), showing how incredibly powerful the cohort patterning of influenza deaths is, in regular (not pandemic) years, corresponding to how circulating strains match up w what people were exposed to as kids
science.org
Childhood immune imprinting shapes cohort and period influenza mortality
Childhood exposure to different influenza strains shapes the age-profile of seasonal influenza mortality.
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bioRxiv Genetics @biorxiv-genetic.bsky.social · 19/05/2025
Mutation-selection-drift balance models of complex diseases www.biorxiv.org/content/10.1101/202…
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Leslie Root @lesja.bsky.social · 08/05/2026
Bhattacharya goes "there were political machinations in the old process too. (pause) I shouldn't say 'too,' I don't believe there are political machinations in the current process" 🫠🫠🫠
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Leslie Root @lesja.bsky.social · 08/05/2026
I need to start keeping a tally of how many times he mentions whole-genome sequencing
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Lara Durgavich @ldurgavich.bsky.social · 01/05/2026
By the early 1900s, the work of Goddard & others had led many Americans to embrace negative eugenics, or the idea that "unfit" individuals should not be allowed to reproduce.
Early 1900s propoganda poster with a drawing of a man spreading seed on a landscape. The text says "Only healthy seed must be sown! Check the seeds of hereditary disease and unfitness by eugenics." Photograph of a 1923 article from Popular Science magazine. The headline is "Registering Human Pedigrees: how Kansas develops filter families; a remarkable experiment in eugenics"
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Post-Viral Trials @postviraltrials.bsky.social · 16/04/2026
The drug is trimetazidine (seems very paternalistic to not mention it)
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Span @anna2.bsky.social · 04/03/2026
A fun paper explainer, with sci fi references
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Span @anna2.bsky.social · 15/02/2026
Rita Levi-Montalcini Thanks for highlighting, this lady’s career is fascinating. “one of the first scientists to point out the importance of the mast cell in human pathology.”
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Ada Palmer @adapalmer.bsky.social · 14/02/2026
Prevention may have wider spillovers than we thought: Eric Topol explores the evidence that older adults who received a shingles vaccine had a roughly 20% lower risk of developing dementia in later years buff.ly/iuMmX9U #ShareGoodNewsToo
buff.ly
Spotlight on the Shingles Vaccine—Again!
Two new studies add to a remarkable body of evidence for benefit
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Span @anna2.bsky.social · 03/02/2026
1490s 💫 reading @adapalmer.bsky.social book Inventing the Renaissance, I lately learn “the #earlymodern “ could be that old* too *for some
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Span @anna2.bsky.social · 02/02/2026
Apt
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Span @anna2.bsky.social · 14/01/2026
“it can be hard not to marvel at certain empirical blind spots that ought not have been there by the middle of the twentieth century.” Yah. Jaw dropping to glimpse the mirror mid century researchers held up to themselves when writing about women patients .
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Scott L Greer @scottlgreer.bsky.social · 11/01/2026
The idea that getting surviving a disease is proof of strength and fitness has deep and largely disgusting roots in American history (see Olivarius’ book). In this case, they are drawing the lOgIcAl conclusion that needless exposure to disease is therefore a valuable test of strength…
hup.harvard.edu
Necropolis — Harvard University Press
Disease is thought to be a great leveler of humanity, but in antebellum New Orleans acquiring immunity from the scourge of yellow fever magnified the brutal inequities of slave-powered capitalism.Ante...
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BCMECR spooky/pumpkin spice mode @b1kes.bsky.social · 19/12/2025
People distrust healthcare, and often it's not the medicine itself. It's because of exceptionally negative experiences with medical "professionals." I'm a white male. And even I have experienced doctors treating me like total garbage. Makes me scared of how marginalized people are treated.
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Span @anna2.bsky.social · 12/12/2025
”Long COVID is sometimes described as an anything-goes sequela. This study shows the opposite. A consistent, reproducible biological signature across independent cohorts.“ (from the Zdenek tweet thread on the nature paper)
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This Podcast Will Kill You @tpwky.bsky.social · 09/12/2025
In this week’s TPWKY book club episode, Dr. Homer Venters joins us to discuss his latest work, Outbreak Behind Bars: Spider Bites, Human Rights, and the Unseen Danger to Public Health. Dr. Venters has extensive firsthand knowledge of the barriers in care - and he has evidence-based solutions.
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Simon Spichak @spichaksimon.bsky.social · 21/11/2025
A few charts we created for this analysis.
A Sankey chart showing the 112 exercise trials. 21 measured PEM and only 4 excluded participants who experienced it.
Bar plot showing the number of Long COVID exercise trials over time that mention PEM in the registration
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Span @anna2.bsky.social · 21/11/2025
Had an exchange not so long ago here on when neuroplasticity approach appropriate. The cause of illness accurately recognised (e.g. a discrete lesion) and not as a cure for impairment but to improve quality of life, post CNS injury for example. Misapplications harm reputation.
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ME/CFS Science @mecfsscience.org · 28/10/2025
2) The authors started with data in the UK Biobank. They looked for cases with MS, Crohn's disease, ulcerative colitis, and atopic dermatitis using their ICD-10 health records. Next, they used the genetic data of these participants to screen for disease–causing mutations.
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Laura Spinney @laurainparis.bsky.social · 29/10/2025
We're beginning to see how disease shaped (pre)history. www.newscientist.com/article/2500...
newscientist.com
How a surge in ancient plagues 5000 years ago shaped humanity
Plague, leprosy, smallpox and other diseases didn't jump from animals to humans when we thought. Ancient DNA is revealing where they come from and how they changed history
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Miska Knapek @miskaknapek.bsky.social · 27/07/2025
(kindly share) I'm selling photos to raise money private medical help for a severe - quite lifeshortening - immune damaging disease I have, #MECFS, outside the coverage of public health. There are some good nature photos in any event ;) More info here: payhip.com/MiskaKnapek/...
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Span @anna2.bsky.social · 13/09/2025
@cgatist.bsky.social @decodemestudy.bsky.social @openmedf.bsky.social
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This Podcast Will Kill You @tpwky.bsky.social · 11/09/2025
Last ep, we took you through all the ways that cold can harm us. Ending the story there would be skipping over the parts where cold is the hero, rather than the villain. In the second of this frosty miniseries, we explore situations in which we might use cold to protect us and how it actually works.
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Ada Palmer @adapalmer.bsky.social · 09/08/2025
A very important point! When my cognitive stuff started making long form reading intermittently impossible, I adopted a variety of tools to still engage w/ my craft: audiobooks, graphic novels, short fiction, film adaptations of books & plays, the mix has & hones the tools of writing really well 1/2
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