a blog for miscellaneous bioinformatics stuff

Nature - Telomere-to-Telomere Assembly Using HERRO-Corrected Simplex Nanopore Reads

Analyses of epidemiological, clinical and molecular data from a prospective cohort of 3,100 patients with esophageal carcinoma suggest intestinal metaplasia as a single precancer pathway preceding the...

In a real-world cohort of 888 patients with solid cancers receiving whole-genome sequencing profiling, actionable biomarkers were identified in 73% of patients, and targeted therapies were associated ...

Nanopore sequencing enables real-time, long-read analysis by processing raw signals as they are produced. A key step, segmentation of signals into events, is typically handled algorithmically, struggl...

The Somatic Mosaicism across Human Tissues Network aims to create a reference catalogue of somatic mosaicism across different tissues and cells within individuals.

Scientists must push back against the threat of rising white nationalism and the dangerous and pseudoscientific ideas of eugenics.

Tumoroids are cultures of patient-derived tumor cells, which are grown in 3D in the presence of an extracellular matrix extract and specific growth factors. Tumoroids can be generated from adult as we...

I'm happy to announce that I have been awarded the NMRC Open Fund - Young Individual Research Grant (OF-YIRG) for the project: Unveiling Risk Factors of Early-Onset Colorectal Cancers through…

To end the year, we want to highlight some of our biggest stories of 2024, including big advances in prevention, diagnosis, and treatment.