Single-cell transcriptomics, spatial transcriptomics and chromatin accessibility maps of the human craniofacial region in developing embryos provide insights into the mechanisms underlying facial vari...

Retrotransposons can infect neighboring cells using a mechanism that relies on a small fusogen-like protein rather than on the envelope protein that is typically required for infection.

The Pulitzer prizewinner shares his advice for pleasing readers, editors and yourself.

In the last decade, there has been an explosion in the development of in vivo germline genetic editing technologies in arthropods, first pioneered by the Receptor-Mediated Ovary Transduction of Cargo ...

As a fundamental biological principle, genomic information is typically transmitted vertically from parent to offspring. Occasionally, however, genetic material is transferred horizontally between spe...

Find out why there is still no second part in my series on Drosophila TE names — and how I spent my summer instead.

⭐ We are recruiting an M2 student for a 6-month internship in Montpellier in 2027!   Together with Albert Tsai, we are looking for a motivated Master 2 student to join our collaborative project: From ...

Inflammation induces interchromosomal DNA interactions that bring parent genes into close proximity, facilitating the formation of chimeric mRNAs that encode physiologically relevant, functional prote...

Transposable-element (TE) abundance can vary substantially among populations, yet population-specific differences in TE content remain incompletely characterized. Here, we compared known TE families a...

Arteriovenous fistulas are the most common vascular access points for hemodialysis, but they have a high incidence of postoperative dysfunction, mainly due to excessive neointimal hyperplasia. Here, t...

Super-enhancers have been proposed to cluster in the nucleus when compared to other genomic elements. Le et al. found that super-enhancer clustering was rare and driven by non-specific interactions. P...

A postdoctoral scholarship within the project “Transposable elements and the aging human brain: Functional Insights and therapeutic opportunities”

In Metazoa, transposon expression is suppressed by the piRNA pathway, and disruption of this pathway leads to rampant transposon expression. However, it remains unclear whether increased transposon ex...

Repbase and Dfam, the two foundational resources for transposable element annotation, are being unified into a single, fully open access framework, with Repbase released under CC-0 and its core curati...

Gregory J. Hannon passed away in April 2026 at the age of 61. A towering figure in modern molecular biology, Greg influenced remarkably diverse areas of science. His work reshaped our understanding of gene regulation, advanced the discovery of tumor suppressors that regulate the cell-cycle machinery, and uncovered fundamental mechanisms of RNA interference. By establishing core principles of small RNA biology, he not only transformed our mechanistic view of RNA-silencing pathways but also pioneered functional genomics approaches that revolutionized basic and biomedical research in mammalian systems.

Movement of genetic material between non-parental organisms, called horizontal gene transfer (HGT), is well recognized in prokaryotes but represents an underestimated force for the acquisition of nove...