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Laura Winchester

@winchesterl.bsky.social
589 followers 709 following 36 posts

Dementia researcher @ Oxford University | Working on multiomics & bioinformatics Mum | runner | cat owner She / her

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Laura Winchester @winchesterl.bsky.social · 17/08/2026
Recovering from a broken leg this is the only cone of shame he can't break out of. He is not happy about it but still worth a photo for #blackcatappreciationday
Angry black cat in green cone of shame collar.
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Dementia Researcher @dementiaresearcher.bsky.social · 27/07/2026
Meet @winchesterl.bsky.social an Oxford Associate Professor shaping dementia research with integrative genomics, proteomics, and ML. From biomarkers to therapeutic insights, her work spans multi-omics, biobanks, and real-world data 🧠🔬 www.dementiaresearcher.nihr.ac.uk/profile-dr-l...
dementiaresearcher.nihr.ac.uk
Profile – Dr Laura Winchester, University of Oxford - DEMENTIA RESEARCHER
Dr Laura Winchester is an Oxford Associate Professor using genomics, proteomics and machine learning to uncover disease mechanisms and biomarkers in dementia.
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Laura Winchester @winchesterl.bsky.social · 09/06/2026
🧠📊 Join us for the JUNE DEMON Biomarkers Working Group 📅 10 June 2026 ⏰ 10:00–11:00 BST Online. We're pleased to host Dr Henry Musto presenting "Survival-Based AI for Dementia Prognosis Prediction". Please message for joining details. #academicsky #dementiaresearcher
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Cristina Legido-Quigley @legidoquigley.bsky.social · 10/05/2026
Our latest preprint is out and we found that sugar derivatives are increased in Alzheimer's Disease & identified a pathway that could be modulated www.medrxiv.org/content/10.6...
medrxiv.org
Polyol pathway dysregulation in CSF links glucose metabolism to tau pathology inde-pendently of amyloid and genetic predisposition
Dementia affects approximately 60 million people worldwide, yet molecular mechanisms linking early neuropathological changes to clinical progression remain poorly understood. We performed targeted and...
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Laura Winchester @winchesterl.bsky.social · 01/06/2026
New preprint using the Biohermes cohort to explore amyloid protein signatures. #proteomics
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Laura Winchester @winchesterl.bsky.social · 01/06/2026
Stumbled across the Luminarium with my daughter for a sunday afternoon lesson in visual light. #architectsofair @harwellcampus
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Laura Winchester @winchesterl.bsky.social · 10/05/2026
Brilliant work from @joshuasammet.bsky.social and so pleased to see his hard work in print
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Sarah Harris @saraheharris99.bsky.social · 10/09/2025
Calling for your paper for the upcoming collection Brain metabolomics in dementia and neurological disease I’m honoured to be serving as the collection’s Guest Editor and eager to read your submission. #CallForPapers @natureportfolio.nature.com Learn more about the collection: go.nature.com/41S5bI3
go.nature.com
Brain metabolomics in dementia and neurological disease
This Collection invites original research using metabolomic platforms to explore the mechanisms of dementia and neurological disease or aid in its diagnosis ...
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Laura Winchester @winchesterl.bsky.social · 12/01/2026
January @DEMONNetworkUK Biomarkers working group is hosting an Inflammation special with Dr Maura Malpetti and Dr Sofia Michopoulou “Unravelling Inflammation in Dementia: Proteomic and Imaging Insights” 📅 Wed 14th Jan 10.30am GMT. New members welcome - pls message for details.
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Laura Winchester @winchesterl.bsky.social · 05/01/2026
Trying to finish a grant submission while child plays the Imperial March on the kazoo. I hate inset days and also Santa for gifting kazoos this year.
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Conceicao Bettencourt @saobettencourt.bsky.social · 05/01/2026
Happy New Year everyone! 🚨Join our first @DEMONNetworkUK #Genetics #Omics meeting of 2026 - THURSDAY 8th January at 2.30 PM (UK Time). Delighted to have Juan Botia as invited speaker – “Using graph neural networks to expand what we know about neurodegeneration” Join the network or DM for more info
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Laura Winchester @winchesterl.bsky.social · 01/01/2026
Giant lazer celebrations from the diamond light source for new year. #thebeam
The beam laser source from harwell campus
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Laura Winchester @winchesterl.bsky.social · 29/12/2025
Post Christmas work message but finally got our longitudinal proteomics study of Parkinson's subtypes into preprint this month. Dedicated mechanistic modules for 🧠+🩸using the Tracking Parkinson's and GNPC cohorts #parkinsons #academicSky #proteomics www.biorxiv.org/content/10.1...
biorxiv.org
Longitudinal Proteomic Profiling Defines Robust Molecular Subtypes Underlying the Heterogeneity of Parkinson’s Disease
Heterogeneity of Parkinson’s disease (PD) pathology is a barrier to developing therapeutics and understanding progression and prognosis. High throughput proteomic measures can be used to better interp...
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Helen Barrett @helenbarrett.bsky.social · 18/12/2025
Good news at last. www.ctvnews.ca/health/artic...
ctvnews.ca
Study finds potential link between high-fat cheese and lower risk of dementia
A study out of Sweden has looked at the possible link between eating more high-fat cheese, like cheddar, gouda and brie, and a lower risk of developing dementia.
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Dementia Researcher @dementiaresearcher.bsky.social · 21/11/2025
There is still time to register for today Fluid and Neuroimaging Biomarker Forum discussion - todays chat will explore sample handling and data interpretation. 12pm GMT in the Dementia Researcher Community communities.dementiaresearcher.nihr.ac.uk/c/live-poste...
communities.dementiaresearcher.nihr.ac.uk
Fluid and Neuroimaging Biomaker Forum
Fluid and Neuroimaging Biomaker Forum
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Laura Winchester @winchesterl.bsky.social · 01/11/2025
Joint DEMON network working group this month discussing female specific lipid expression in #Alzheimer’s. Please pm me or @saobettencourt.bsky.social for more details. #academicsky ⬇️
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Laura Winchester @winchesterl.bsky.social · 26/10/2025
Enjoying the skeleton hard at work in his lab in this year's local Halloween trail.
Plastic Skeleton in his woodland lab wearing appropriate safety equipment (goggles and lab coat).
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Laura Winchester @winchesterl.bsky.social · 09/10/2025
Last training run yesterday before the Oxford half on Sunday. Running for Alzheimer’s Research UK and still looking for sponsors. And please have a look at all the other ARUK researchers running this weekend. @arukthamesv.bsky.social www.justgiving.com/fundraising/...
Slightly muddy running footpath alongside a farmers field somewhere in darkest Oxfordshire.
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Laura Winchester @winchesterl.bsky.social · 24/09/2025
This is an interesting one for potential reviewers. The authors used the NHANES cohort publications to count the copycats.
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Clare Mackay @claremackay.bsky.social · 20/09/2025
Big news! I loved researching and writing this book, which is all about shedding the shame, and getting really curious about urges to pick, pull and bite. I can't wait to share it with you! It's out on April 2nd, and is available to pre-order now. #bfrb #bfrbs #bodyfocusedrepetitivebehaviors
Picuture showing forthcoming book, called 'Keep your hair on: understanding urges to pick, pull and bite' by Clare Mackay, which will be launched in April 2026
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Laura Winchester @winchesterl.bsky.social · 20/09/2025
Enjoying this as a distraction this morning as well...
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Laura Winchester @winchesterl.bsky.social · 20/09/2025
My moral support for responding to reviewers on a Saturday morning. He's fed up as well. #Caturday
Black cat lying on a sofa
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Dementia Researcher @dementiaresearcher.bsky.social · 15/09/2025
Who’s ready for Manchester 2026? 🧠 AAIC Neuroscience Next is free, global, and packed with chances to present your work. Abstracts open 22 September – are you in? #AAICNeuro pod.fo/e/329e2b
pod.fo
Dementia Researcher: The Road To AAIC Neuroscience Next 2026
In this episode of the Dementia Researcher podcast, host Adam Smith discusses the upcoming AAIC Neuroscience Next Conference with guests Tricia Nicholson, Dr Amanda Heslgrave, and Kalli Mavr...
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Laura Winchester @winchesterl.bsky.social · 15/08/2025
Starting the training runs for Oxford half from the beach this morning. Will be looking for sponsorship when I get home ... www.justgiving.com/team/aruk-ru...
Beach over sand dunes with sun behind cloudsRunning path along the beach
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Iris van Rooij 💭 @irisvanrooij.bsky.social · 12/08/2025
AI slop and the destruction of knowledge irisvanrooijcogsci.com/2025/08/12/a...
irisvanrooijcogsci.com
AI slop and the destruction of knowledge
This week I was looking for info on what cognitive scientists mean when they speak of ‘domain-general’ cognition. I was curious, because the nuances are relevant for something I am researching at t…
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Dylan Williams @dylwil.bsky.social · 12/08/2025
Just came across this graphical abstract for a paper. No idea what they were going for with the whale and rainbow, but at least it is very calming
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Laura Winchester @winchesterl.bsky.social · 15/07/2025
Big day for @neuroproteome.bsky.social All proteomic data released at neuroproteome.org and publications in print. Lots to read on AD, PD, FTD and ALS.
neuroproteome.org
GNPC
The Global Neurodegeneration Proteomics Consortium (GNPC) has brought together top dementia researchers to collaborate on proteomic and associated clinical data analysis to understand and transform patient trajectories.
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Laura Winchester @winchesterl.bsky.social · 25/06/2025
Looking for a new PhD student interested in Alzheimer’s disease and informatics starting in October. Details below.
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Laura Winchester @winchesterl.bsky.social · 06/06/2025
For the June DEMON Biomarker working group we are pleased to host Dr Ehsan Pishva who will be presenting his work on DNA methylation and environmental exposures in Parkinson’s disease. Wednesday 11th June 10am BST. Please message for joining links.
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UK Dementia Research Institute @ukdri.ac.uk · 06/05/2025
🚨Calling all ECRs working on dementia biomarkers! 🚨 Are you interested in helping us shape the scientific programme for a one-day conference in February 2026? Find out more & register your interest 👉 www.dementiaresearcher.nihr.ac.uk/help-design-...
dementiaresearcher.nihr.ac.uk
Help Design a Pioneering Dementia Biomarkers Conference - DEMENTIA RESEARCHER
Are you an ECR working on dementia biomarkers? Help shape a major 2026 conference & UK AAIC hub bid. Volunteer by 11 May to get involved!
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Tom Gauld @tomgauld.bsky.social · 28/04/2025
My latest @newscientist.com cartoon
Title:
SOME GRAMMATICAL VOICES FOR USE IN SCIENTIFIC WRITING

ACTIVE VOICE
e.g.
Our team collected samples and then we tested them.

CLICKBAIT VOICE
e.g.
We collected some samples...
You won't believe what happened next!

PASSIVE VOICE
e.g.
Samples were collected and tested.

HAIKU VOICE
e.g.
Quiet science lab.
Workers arrive with samples.
The testing begins.

PASSIVE-AGGRESSIVE VOICE
e.g. We did all the collecting and testing.
No need to thank us.
Just doing our job.

CONSPIRACY VOICE
e.g.
Mysterious "Samples" were harvested and covertly "tested" by so-called scientists.
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Stephen Turner @stephenturner.us · 14/04/2025
A benchmarking crisis in biomedical machine learning www.nature.com/articles/s41... 🧬🖥️🧪
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Laura Winchester @winchesterl.bsky.social · 07/04/2025
In this month's DEMON Biomarker working group we are looking forward to hearing from @sanasuri.bsky.social who will be discussing her work on predicting dementia risk factors related to the heart and brain. 📅 Wed 9th April 10am (BST). Please message for joining details
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Laura Winchester @winchesterl.bsky.social · 28/03/2025
Sharing on a Friday without the need for any further comment.
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Laura Winchester @winchesterl.bsky.social · 27/03/2025
Lovely paper on cat coat genetics.
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British Society for Immunology @britsocimm.bsky.social · 26/03/2025
Thanks to global immunisation efforts, an estimated 154 million lives have been saved over the past 50 years 🌎 🤝 That’s equivalent to 6 lives every minute. #CelebrateVaccines
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Petra Proitsi @ppetra.bsky.social · 10/03/2025
We're excited to have @dorsaabdolkarimi.bsky.social from @preventiveneur1.bsky.social at our monthly DEMON Biomarkers WG meeting, on Wednesday, 12th March, @ 10am GMT presenting on "Identifying a Signature of Inflammatory Proteins Predicting Dementia." DM me or @winchesterl.bsky.social for details
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Laura Winchester @winchesterl.bsky.social · 27/02/2025
Had a brilliant time in Birmingham this week but I do have to say the Early Careers Day was my favourite this year even if i am biased. Fantastic talks from both early career researchers and our invited experts. #arukconf25
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Cristina Legido-Quigley @legidoquigley.bsky.social · 31/01/2025
I did a list of #WomeinSTEM working in #metabolomics & #lipidomics and #datascience please join or share with others, use it for conferences, media & networking, mentoring, supporting, anything that helps, 300+ women have joined docs.google.com/document/u/0...
docs.google.com
LIST “WOMEN IN METABOLOMICS, LIPIDOMICS, PROTEOMICS AND RELATED DATA SCIENCE”
NAME INSTITUTION COUNTRY Dr. Maria Eugenia Monge CIBION-CONICET Argentina Prof. Elaine Holmes Murdoch University- Imperial College London Australia- UK Dr Ruey-Leng Loo Murdoch University, Au...
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Laura Winchester @winchesterl.bsky.social · 30/01/2025
Next week the DEMON biomarkers working group are hosting Dr Sofia Toniolo who will be talking about the opportunities and pitfalls from digital and plasma biomarkers in Alzheimer’s Disease. 📅 Thursday 6th Feb 10am GMT. All welcome - PM for details.
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Statistical, Translational, and Analytic Genetics Group (KCL) @coleman-group-kcl.bsky.social · 16/01/2025
Just out — great work from Lachlan Gilchrist investigating the genetic relationship between depression and Alzheimer's. Pleased to have been able to contribute a little to this one. Open access, so read all about it below! www.nature.com/articles/s44...
nature.com
Depression symptom-specific genetic associations in clinically diagnosed and proxy case Alzheimer’s disease - Nature Mental Health
Using genome-wide meta-analyses of clinical measures of depression and biobank data, the authors investigate symptom-specific genetic associations between depression and subsequent risk for Alzheimer’...
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Yasset Perez-Riverol @ypriverol.bsky.social · 11/01/2025
Most of this 👇 data is not public, @pride-ebi.bsky.social is trying to change that. Led by @deeptijkundu.bsky.social & our development team, we are building an Affinity Proteomics (AP) Archive. If you have AP data that you can make public, please get in contact. #FAIR #OpenData #proteomics
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Laura Winchester @winchesterl.bsky.social · 10/01/2025
This month the DEMON biomarkers working group have Dr Lazaros Belbasis speaking about his work on Proteome-wide Mendelian randomization to investigate the pathogenesis of Alzheimer’s disease. 📅 Wed 15th Jan 10am GMT. All welcome - PM for details.
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Laura Winchester @winchesterl.bsky.social · 10/01/2025
Brilliant news for UK Biobank researchers!
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Laura Winchester @winchesterl.bsky.social · 01/01/2025
Happy New Year everyone.
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Laura Winchester @winchesterl.bsky.social · 13/12/2024
Looking for new bioinformatics post doc role in 2026? 3 year contract working on proteomic data for AD and PD in Oxford. Do get in touch with any questions - would love to hear from you. #Proteomics #AcademicSky
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Laura Winchester @winchesterl.bsky.social · 09/12/2024
📢 December DEMON Network Biomarkers working group will host Dr Alankar Atreya discussing how changes in sleep detected by wrist devices are related to Alzheimer's progression. ⌚️ Wed 11th 10am GMT. All welcome - please message for teams details.
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Sana Suri @sanasuri.bsky.social · 03/12/2024
New 🫀🧠 paper in eBiomedicine: we show that BMI, blood pressure, and physical activity in childhood and adolescence are linked with early structural differences in brain regions that are known to be affected in dementia. www.sciencedirect.com/science/arti...
sciencedirect.com
Association of early life cardiovascular risk factors with grey matter structure in young adults in the United Kingdom: the ALSPAC study
Cumulative exposures to obesity, hypertension, and physical inactivity from midlife (40–65 years) onwards are three known cardiovascular risk factors …
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Johanna Joyce @johannajoyce.bsky.social · 25/11/2024
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️ So how can we ever achieve #gender #equality? We discuss various strategies in this #Cell Commentary #WomeninSTEM www.cell.com/cell/fulltex... 🧵 1/
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Silvia Paracchini @silparacchini.bsky.social · 22/11/2024
Biobanking with genetics shapes precision medicine and global health doi.org/10.1038/s415...
doi.org
Biobanking with genetics shapes precision medicine and global health - Nature Reviews Genetics
Biobanks help centralize specimen collections, store and disseminate data, and facilitate large-scale analyses. This Review discusses how biobanks facilitate genetics research towards advancing precis...
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