Cristina Legido-Quigley @legidoquigley.bsky.social · 22/08/2026follow me for camouflage advice #caturday 1130
Cristina Legido-Quigley @legidoquigley.bsky.social · 28/07/2026Our latest preprint www.linkedin.com/posts/cristi...linkedin.com💊 Our latest preprint 💊 We study liraglutide-induced molecular lipid remodelling in type 2 diabetes. Using targeted lipidomics we show that GLP-1 RA treatment remodels the lipid profile, shifting… |...💊 Our latest preprint 💊 We study liraglutide-induced molecular lipid remodelling in type 2 diabetes. Using targeted lipidomics we show that GLP-1 RA treatment remodels the lipid profile, shifting fr... 020
Reposted by Cristina Legido-QuigleyAdmirable Women @admirablewomen.bsky.social · 24/07/2026Amelia Earhart was born #OTD in 1897. 🛩️ 1929: Co-founded The Ninety-Nines & was its first president 🛩️ 1932: First woman/second person to fly solo/nonstop across the Atlantic 🛩️ 1935: First person to fly solo from Hawaii to California 🛩️ 1937: Disappeared somewhere over the Pacific #Aviation #AvGeek 114548
Reposted by Cristina Legido-QuigleyGeorge Davey Smith @mendelrandom.bsky.social · 22/07/2026Does the (live) shingles vaccine protect against dementia? Fergus Hamilton and colleagues provide important evidence in a new preprint using hospital data from the whole of England in a regression discontinuity design from which we *don't* show evidence of a meaningful protective effect /cont 38245
Cristina Legido-Quigley @legidoquigley.bsky.social · 15/07/2026Our latest paper is out, looks at hormones in Alzheimer's Disease please see as open access publication link.springer.com/article/10.1...link.springer.comSteroid hormones in Alzheimer’s disease: a molecular analysis of blood and cerebrospinal fluid - Alzheimer's Research & TherapyBackground Alzheimer's disease (AD) disproportionately affects women, yet existing studies have been limited to single biofluids, individual hormones, or single dementia subtypes, leaving sex-stratifi... 001
Cristina Legido-Quigley @legidoquigley.bsky.social · 06/06/2026Good weekend from a rainy London #caturday #flowers 080
Reposted by Cristina Legido-QuigleyAdmirable Women @admirablewomen.bsky.social · 31/05/2026Dr. Patricia Bath overcame sexism, racism & poverty and saved the sight of millions of people. She invented the Laserphaco Probe for cataract treatment, 1986; it was patented in 1988. She co-founded the American Institute for the Prevention of Blindness, 1976. She died #OTD in 2019. #WomenInSTEM 143114592709
Reposted by Cristina Legido-QuigleyAdmirable Women @admirablewomen.bsky.social · 30/05/2026Physicist Rosalyn Yalow co-invented a super-sensitive test (radioimmunoassay) that uses tiny amounts of radioactive tags to detect exact levels of insulin in blood & won the 1977 Nobel Prize in Physiology or Medicine (the 2nd woman ever to win in this category). She died #OTD in 2011. #WomenInSTEM 51070234
Reposted by Cristina Legido-QuigleyAmélie Cabirol @acabirol.bsky.social · 21/05/2026Really happy to see our paper finally published in PNAS 🎉 We used honey bees to study how gut microbiota shape cognition and found that learning benefits only appear when the full microbial community is present — not with individual bacterial species alone. www.pnas.org/doi/10.1073/... 2205
Reposted by Cristina Legido-QuigleyCell Reports Medicine @cp-cellrepmed.bsky.social · 16/05/2026Online now: Healthful plant-based diet, gut enterotype, and cognition in a rural Chinese elderly cohort: A longitudinal multi-omics studydlvr.itHealthful plant-based diet, gut enterotype, and cognition in a rural Chinese elderly cohort: A longitudinal multi-omics studyShen et al. report that a healthful plant-based diet is associated with distinct gut microbiome features and a 12-metabolite signature. The diet-cognition association varied by gut microbiome enterotype, with stronger benefits in individuals with non-Prevotella-dominant enterotypes. These findings suggest that gut microbial context may shape diet-cognition associations in later life. 041
Reposted by Cristina Legido-QuigleyDementia Researcher @dementiaresearcher.bsky.social · 15/05/2026Wellcome Discovery Awards fund established researchers and teams to pursue bold ideas that advance health and wellbeing research. www.dementiaresearcher.nihr.ac.uk/funding/well...dementiaresearcher.nihr.ac.ukWellcome Discovery Awards - DEMENTIA RESEARCHERWellcome Discovery Awards fund established researchers and teams to pursue bold ideas that advance health and wellbeing research. 001
Reposted by Cristina Legido-Quigleyfravery.bsky.social @fravery.bsky.social · 11/05/2026Never be in a hurry; do everything quietly and in a calm spirit. Do not lose your inward peace for anything whatsoever, even if your whole world seems upset. ~ Francis de Sales Je Shen (China b. 1973) 583753560
Cristina Legido-Quigley @legidoquigley.bsky.social · 10/05/2026Our latest preprint is out and we found that sugar derivatives are increased in Alzheimer's Disease & identified a pathway that could be modulated www.medrxiv.org/content/10.6...medrxiv.orgPolyol pathway dysregulation in CSF links glucose metabolism to tau pathology inde-pendently of amyloid and genetic predispositionDementia affects approximately 60 million people worldwide, yet molecular mechanisms linking early neuropathological changes to clinical progression remain poorly understood. We performed targeted and... 011
Cristina Legido-Quigley @legidoquigley.bsky.social · 02/05/2026hard work this business of making biscuits #caturday #catsofsky 0141
Reposted by Cristina Legido-QuigleyEric Topol @erictopol.bsky.social · 30/04/2026First randomized trial to show Ozempic reduces alcohol consumption in people seeking treatment for alcohol use disorder. Placebo-controlled, double-blind. Participants with BMI >30 kg/m2. thelancet.com/journals/lan...thelancet.comOnce-weekly semaglutide versus placebo in patients with alcohol use disorder and comorbid obesity: a randomised, double-blind, placebo-controlled trialSemaglutide showed robust therapeutic effects in treatment-seeking participants with obesity and alcohol use disorder and this trial supports previous preclinical and clinical findings suggesting GLP-... 323062
Reposted by Cristina Legido-QuigleyEuropean Medical Journal @emjreviews.com · 01/05/2026Cognitive decline may begin up to 8 years before a heart attack or stroke. ASPREE data from 9,400+ adults shows faster deterioration across memory, fluency & cognition well before cardiovascular events. Explore the findings: www.emjreviews.com/neurology/ne...emjreviews.comCognitive Decline May Precede Cardiovascular EventsCognitive decline may begin years before major cardiovascular events in older adults, according to long-term study data. 021
Reposted by Cristina Legido-QuigleyJeremiah Cohen @jeremiahycohen.bsky.social · 13/04/2026Delighted to share our discoveries about one of the brain's neurotransmitter systems: www.biorxiv.org/content/10.6... Together with colleagues at the @alleninstitute.org, we have learned a lot about a tiny cluster of neurons in the brainstem locus coeruleus (LC) that releases norepinephrine (NE). 1biorxiv.org 7254120
Reposted by Cristina Legido-QuigleyIan Kremer @wolverinebear.bsky.social · 13/04/2026SuperAgers show unique cell signatures in the brain www.nih.gov/news-events/... #Alzheimers #dementia #health #wellness #geroscience #neuroscience #NeuroSkyencenih.govSuperAgers show unique cell signatures in the brainResearchers linked neuron creation to exceptional recall and memory in older adults. 097
Reposted by Cristina Legido-Quigleywomensartbluesky.bsky.social @womensartbluesky.bsky.social · 22/03/2026'The Stacks' by UK textile artist Rachel Wright, machine embroidered on calico with various fabrics #womensart 101416237
Cristina Legido-Quigley @legidoquigley.bsky.social · 18/03/2026Sunrays in London are never going to waste #catsofsky #bsh 010
Cristina Legido-Quigley @legidoquigley.bsky.social · 10/03/2026Trends I've noticed in my underground commute in London, men with red socks, many people reading books, women with blue hair 010
Reposted by Cristina Legido-QuigleyIan Kremer @wolverinebear.bsky.social · 05/03/2026Yale study challenges notion that aging means decline, finds many older adults improve over time ysph.yale.edu/news-article... #Alzheimers #dementia #aging #geriatrics #gerontology #healthysph.yale.eduYale study challenges notion that aging means decline, finds many older adults improve over timeAging in later life is often portrayed as a steady slide toward physical and cognitive decline. But a new study by scientists at Yale University suggests an 34522
Reposted by Cristina Legido-QuigleyGabby Zapata @gabbyzapata.bsky.social · 05/03/2026I created a free pdf of a memory companion discreet card for your loved ones with a medical condition. As my moms caregiver for Alzheimer’s, I find these incredibly useful. English & Spanish! No strings attached, just a daughter that cares ♡ #caregiver #alzheimers shopgabbyzapata.com/products/mem...shopgabbyzapata.comMemory CardsAs my mom's caregiver for Alzheimer's, I am sharing a free downloadable printable pdf of memory cards you can hand out to people in tricky situations. This is a discreet way of letting someone know yo... 1149
Cristina Legido-Quigley @legidoquigley.bsky.social · 04/03/2026It's #WhiskersWednesday and Titi finally likes a toy, on close inspection it is filled with catnip 010
Reposted by Cristina Legido-QuigleyEL PAÍS @elpais.com · 01/03/2026“Sigamos celebrando la música diferente, los idiomas diferentes”. Rosalía gana el premio BRIT Internacional y canta ‘Berghain’ junto a Björksocial.elpais.comRosalía gana el premio BRIT Internacional y canta ‘Berghain’ junto a Björk: “Sigamos celebrando la música diferente, los idiomas diferentes”La catalana convirtió el escenario en el famoso club berlinés y montó su propia rave junto a un grupo de bailarines 0669
Reposted by Cristina Legido-QuigleyScientific American @sciam.bsky.social · 26/01/2026Why does being awake and alive, being yourself, feel like anything at all, and where does this singular sense of awareness come from in the brain?scientificamerican.comInside the incredible, infuriating quest to explain consciousnessWill brain science deliver answers about consciousness or hit another wall? 312329
Reposted by Cristina Legido-QuigleyFerwen @ferwen.bsky.social · 24/01/2026Margaret W. Rossiter coined the term “Matilda effect” to describe the bias against acknowledging the achievements of women scientists. Some cases illustrating the Matilda effect include Eunice Foote, Rosalind Franklin, & Jocelyn Bell Burnell #Womeninstem paleonerdish.wordpress.com/2022/03/07/e...paleonerdish.wordpress.comEunice Foote, climate change, and the Matilda EffectThe birth of modern science was hostile to women’s participation. The world’s major academies of science were founded in the 17th century: the Royal Society of London (1662), the Paris Académie Roy… 9868342
Reposted by Cristina Legido-QuigleyAdmirable Women @admirablewomen.bsky.social · 24/01/2026Marjory Stephenson was born #OTD in 1885 + Helped establish modern microbial biochemistry + Wrote foundational textbook 𝘉𝘢𝘤𝘵𝘦𝘳𝘪𝘢𝘭 𝘔𝘦𝘵𝘢𝘣𝘰𝘭𝘪𝘴𝘮 (1930), shaping the discipline for decades + Co-founded, Society for General Microbiology + 1 of the first 2 women Fellows, Royal Society, 1945 #WomenInSTEM 212259551
Cristina Legido-Quigley @legidoquigley.bsky.social · 25/01/2026😂 too funny not to share, we need a cat catching an invisible spider 041
Reposted by Cristina Legido-QuigleyClaire Murray @drclairemurray.com · 19/01/2026This is one for all the #WomeninSTEM. If you are happy to, could you share some of the more awkward and unusual questions you have been asked? The ones your male colleagues would never be asked. I'm running an event @helmholtz.de with the awesome Michelle Browne for #IDWAGIS 212231
Reposted by Cristina Legido-QuigleyAdmirable Women @admirablewomen.bsky.social · 19/01/2026Atmospheric chemist Susan Solomon was born #OTD in 1956. Solomon, working with colleagues at NOAA, proposed/confirmed the cause of the Antarctic ozone hole, chlorofluorocarbons. She led the Nat'l Ozone Expedition to Antarctica to collect evidence & was the only woman on the team. #WomenInSTEM (1/2) 10924188
Reposted by Cristina Legido-QuigleyPhil Lewis @phillewis.bsky.social · 19/01/2026Dr. Gladys West, the pioneering mathematician whose work laid the foundation for modern GPS technology, has died. She was 95.thezebra.orgDr. Gladys West, Mathematician Whose Work Made GPS Possible, Dies at 95ALEXANDRIA, VA — Dr. Gladys West, the pioneering mathematician whose work laid the foundation for modern GPS technology, has died. She passed away 545270729544
Reposted by Cristina Legido-QuigleyPastelBio @pastelbio.bsky.social · 14/01/2026News in Proteomics Research blog post | Super fast targeted proteomics on an ion trap for IBD monitoring! proteomicsnews.blogs... --- #proteomics #prot-other 011
Reposted by Cristina Legido-QuigleyKameron Hurley @kameronhurley.com · 03/01/2026Pretty cool www.bbc.com/news/article...bbc.comHuntington's disease successfully treated for first timeOne of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC. 10111142551
Cristina Legido-Quigley @legidoquigley.bsky.social · 02/01/2026I was convinced today is #caturday 020
Cristina Legido-Quigley @legidoquigley.bsky.social · 01/01/2026Happy 2026!!! A colder than usual dip in Sitges Barcelona, 4C 🥶 sunny 051
Cristina Legido-Quigley @legidoquigley.bsky.social · 18/12/2025Interesting, in my lab we measure near 1000 lipids in blood CSF brain, & we have found that many fats are needed for a healthy brain. Plenty genes that are risk of dementia make proteins that need to interact with fats, to me it makes sense 150
Cristina Legido-Quigley @legidoquigley.bsky.social · 18/12/2025playful mood two months since adoption, more & more trusting, picking up a drama #caturday #catsofbluesky #whiskerswednesday 050
Cristina Legido-Quigley @legidoquigley.bsky.social · 10/12/2025Looking very pleased with her Liberty's collar made by Lorraine at MoogyandPooch 041
Reposted by Cristina Legido-QuigleyLarry the Cat @number10cat.bsky.social · 01/12/2025On the first day of Christmas my true love gave to me, a partridge in a pear tree. Ate it. 1214242581
Reposted by Cristina Legido-QuigleyKarsten Suhre @ksuhre.bsky.social · 27/11/2025Suspense ! Our new #GWAS with MS #proteomics paper has been scheduled for publication in Nature Genetics on 27 November 2025 at 10:00 (London time) and will be available at the following URL: www.nature.com/articles/s41...nature.com 186
Reposted by Cristina Legido-QuigleyTapasDeCiencia @tapasdeciencia.bsky.social · 26/11/2025🧠 Los científicos han descubierto que el cerebro no envejece de forma lineal, sino que cambia de rumbo cuatro veces a lo largo de la vida. Cada giro marca una edad oculta con consecuencias profundas para nuestra memoria, aprendizaje y salud mental. www.rexmolon.es/rexmolon-pro... 211733
Reposted by Cristina Legido-QuigleyPastelBio @pastelbio.bsky.social · 23/11/2025The pursuit of ultrasensitive phosphoproteomics to unravel signalling in rare cells www.nature.com/artic... --- #proteomics #prot-paper 072
Reposted by Cristina Legido-QuigleySimon Schultz @simonschultz.bsky.social · 23/11/2025An update of one of our papers has been posted to biorxiv. Stas, Yang, Schultz and Go, "Longitudinal three-photon imaging for tracking amyloid plaques and vascular degeneration in a mouse model of Alzheimer's disease". www.biorxiv.org/content/10.1... 1193
Reposted by Cristina Legido-QuigleyPaintings of London @paintingsoflondon.bsky.social · 19/11/2025'Cab in Dean St' by Jonathan Stewardson jonathanstewardson.com ------ 🎵 'A Rainy Night in Soho' by The Pogues youtu.be/PSyL-TrD_2g?... 119432
Reposted by Cristina Legido-QuigleyPaintings of London @paintingsoflondon.bsky.social · 21/11/2025'A late delivery on Shaftesbury Avenue' by Tushar Sabale ------ 🎵 'London is the Place for Me' by Lord Kitchener youtu.be/dGt21q1AjuI?... 211616