Reposted by Silvia Paracchini
Nature research paper: Lifespan single-cell transcriptomic atlas of the human prefrontal cortex
go.nature.com/4cZeZ8P
go.nature.com
Lifespan single-cell transcriptomic atlas of the human prefrontal cortex - Nature
The dorsolateral prefrontal cortex exhibits non-linear, cell-type-specific transcriptional trajectories characterized by dynamic remodelling during development, relative stability in midlife and selective molecular reactivation in late adulthood.