Join us for a journal club focused on organelle biology of Plasmodium using spatial proteome analysis, with the lead author, Scott Chrisholm

World Chagas Disease Day acts as a reminder of a global health challenge that often goes unnoticed. Manu De Rycker shares what his team are doing to combat this disease.

MPM LMIC award details

Author summary Infection with Cryptosporidium causes diarrhoea, which can be fatal for malnourished children or people who are immunocompromised. There is no vaccine or effective medicines available t...

Bringing together ECR parasitologists from across Scotland to network and showcase their science.

DNA replication initiates at genome sites termed origins. Previous origin mapping approaches in the populations of the protozoan parasite Leishmania m…

Diplonemids are highly diverse and abundant marine plankton with significant ecological importance. However, little is known about their biology, even in the model diplonemid Paradiplonema papillatum ...

In schistosomiasis-endemic regions, the cyclical nature of infection and treatment complicates understanding of host immune responses. Repeated controlled human Schistosoma mansoni infection, designed...

SPPIRIT would like to invite you to join our series of meetings - the SPPIRIT Forum! The forum is a platform where we will discuss parasitology, funding applications, experimental methods, and other t...

MMV announces new partnership using AI-powered image analysis to accelerate malaria drug discovery. The platform will improve identification of compounds with novel modes of action that can help comba...

Quinazolines targeting Trypanosoma cruzi lysyl-tRNA synthetase show partial efficacy in a mouse model of acute Chagas disease.

Chagas disease, caused by infection with the protozoan parasite Trypanosoma cruzi (T. cruzi), is responsible for a large health burden with around 6–8 million people infected globally. The current dru...

Abstract. Population genetic analysis of mosquitoes is important for understanding the distribution of insecticide resistance alleles, devising sustainable

Transcription in trypanosomatids, such as Trypanosoma brucei, is predominantly polycistronic and involves unconventional RNA polymerase II promoters. This study uses precision gene editing, site-satur...

Transcription in trypanosomatids, such as Trypanosoma brucei, is predominantly polycistronic and involves unconventional RNA polymerase II promoters. This study uses precision gene editing, site-satur...

Chemotherapy remains a key component of the arsenal of tools to fight malaria. Specifically, new drugs with diverse mechanism(s) of action are required to combat existing drug resistance. Here, we des...

Author summary Mammalian infection with schistosome worms results in the deposition of parasite eggs in the liver, where they secrete organ damaging toxins. In response, the liver generates a cellular...

Job description We are recruiting postdocs to contribute to research projects in the Mathematical Modelling of Infectious Diseases Unit, at Institut Pasteur in Paris. The candidates will be expected t...

Here the authors demonstrate that the assembly of mitochondrial respiratory supercomplex (III2–IV) from Toxoplasma gondii is critical for parasite fitness. They reveal the basis for cytochrome b inhib...