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Vini John

@vjohn07.bsky.social
84 followers 173 following 6 posts

Post-doc at Frey lab @ CHLA. Interested in studying mucosal immunity.

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Reposted by Vini John
Payal Yokota @payalyokota.bsky.social · 28/03/2026
Seven subsets, two fates: mouse γδ T cells in cancer immunity: Trends in Immunology www.cell.com/trends/immun... @coffeltlab.bsky.social #gdTcells
cell.com
Seven subsets, two fates: mouse γδ T cells in cancer immunity
The importance of γδ T cells in cancer, as defenders against tumorigenesis, was established more than 2 decades ago. Since that time, research using mouse models of cancer has brought to light a nonun...
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Nick Collins @nick-collins11.bsky.social · 10/02/2026
Also, we're hiring Postdocs and Techs - please reach out if interested!
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Vini John @vjohn07.bsky.social · 07/02/2026
Exciting study on Gamma Delta T cells and colitis!
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Mucosal Immunology @mucosalimmunol.bsky.social · 25/08/2025
Time for the August episode of the #MucosalMonday MI Podcast featuring a discussion with @michael-silverman.bsky.social, @marionbrunck.bsky.social, and Agnes Garcias Lopez; Medical mystery from @ashu-mangalam.bsky.social; and MI research with @kknoop.bsky.social open.spotify.com/show/0Q4Ve1x...
open.spotify.com
Timing Exposure to Microbes
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Mucosal Immunology @mucosalimmunol.bsky.social · 13/08/2025
Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling in this work from @saraalonsomera.bsky.social @edelblumlab.bsky.social and colleagues: www.mucosalimmunology.org/article/S193...
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The American Association of Immunologists @aai.org · 31/07/2025
🚨 AAI is proud to announce the launch of the AAI RESTORE Grants Program, an $8M emergency funding initiative to support scientists whose immunology-focused federal research grants were abruptly terminated or frozen in 2025. 🔗 ow.ly/rwMU50Wy3Mp #AAIRESTORE
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California Institute for Regenerative Medicine (CIRM) @cirmnews.bsky.social · 28/07/2025
It’s great to hear about the various career paths in the #RegenerativeMedicine field—from R&D and lab work to policy and #SciComms. Thank you to our panelists for sharing their experiences and insights. #CIRMTraineeConference
CIRM Trainee Networking Conference career panel sessions discussing their experiences and personal journeys of having a career in regernative medicine.
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γδ T cell Forum @forum-gd.bsky.social · 28/07/2025
Small intestinal γδ T17 cells promote SAE through STING/C1q-induced microglial synaptic pruning in male mice #gdTcells @natcomms.nature.com
nature.com
Small intestinal γδ T17 cells promote SAE through STING/C1q-induced microglial synaptic pruning in male mice - Nature Communications
Sepsis-associated encephalopathy (SAE) is a severe and often fatal consequence of sepsis. Here authors show in a mouse model of sepsis that γδ T17 cells, migrating from the small intestine to the meni...
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Eberl Lab 👨🏻‍🔬👩🏽‍💻🔬🧫 @eberllab.bsky.social · 23/05/2025
The perfect end to a great #gammadeltatoronto conference: our latest review has just been published in Advances in Immunology! "Modulation of humoral immunity by γδ T cells: A potential adjuvant strategy for vaccination" 👉🏼 authors.elsevier.com/a/1l8ltErwXf... #gdTcells @forum-gd.bsky.social
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Amy Engevik @amyengevik.bsky.social · 24/05/2025
Happy #FluorescenceFriday!
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Waggoner Lab @labwaggoner.bsky.social · 23/05/2025
Secretory IgM regulates gut microbiota homeostasis and metabolism @natmicrobiol.nature.com www.nature.com/articles/s41...
nature.com
Secretory IgM regulates gut microbiota homeostasis and metabolism - Nature Microbiology
Rainbow trout with depleted secretory IgM reveal interesting insights into the elusive role of this immunoglobulin in maintaining gut microbiota.
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Eduardo Villablanca @ejvillablanca.bsky.social · 14/05/2025
We’re excited to share our recently published story “A zebrafish model of intestinal epithelial damage reveals macrophages and igfbp1a as modulators of mucosal healing” in @mucosalimmunol.bsky.social Fantastic work led by @ramoralescastro.bsky.social ! www.mucosalimmunology.org/article/S193...
mucosalimmunology.org
A zebrafish model of intestinal epithelial damage reveals macrophages and igfbp1a as major modulators of mucosal healing
The intestine is a semipermeable tissue responsible for the absorption of essential nutrients while limiting exposure to harmful environmental factors. To maintain these functions, the intestinal epit...
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Vini John @vjohn07.bsky.social · 14/05/2025
Check out this paper on the role of ACC1 in γδT17 cells in vivo in a psoriatic mouse model #gdtcells
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Waggoner Lab @labwaggoner.bsky.social · 06/05/2025
Immune–epithelial–stromal networks define the cellular ecosystem of the small intestine in celiac disease www.nature.com/articles/s41... @natimmunol.bsky.social
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Vini John @vjohn07.bsky.social · 06/05/2025
If you are at #AAI25 in Hawaii and interested in learning about intestinal epithelial and IEL crosstalk. Please do stop by my poster # 1107 today from 10:30-11:45am. Session Title: MUC6P -Regulation of Mucosal Immunity. @squeakyanimal.bsky.social #Immunology2025
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Parse Biosciences @parse.bsky.social · 06/05/2025
The Parse team is presenting one more scientific poster this morning at @aai.org! Meet us at board 1187 at 10:30 to learn about how Evercode technology as the only all-in-one solution for humanized transgenic mice. www.parsebiosciences.com/aai-2025/
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Michal Caspi Tal, PhD @immunofever.bsky.social · 06/05/2025
1/ My group is at #IMMUNOLOGY2025 presenting our research. For those of you following along from home I want to share 1 min videos of each presenting their posters. @PaigeSHansen did an incredible job here presenting her about Lyme disease and gynepathologies.
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The American Association of Immunologists @aai.org · 04/05/2025
#ICYMI scenes from #IMMUNOLOGY2025™ from Saturday, May 3! #AAI2025
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Marvic Carrillo Terrazas @marvicct.bsky.social · 03/05/2025
Aloha!🌺 Super excited for another year at #Immunology2025 representing the Chu Lab👩🏻‍🔬 @chulab.bsky.social This time I’ll be sharing the induction of pro-inflammatory responses by B. fragilis isolated from an IBD patient👀 Want to hear all about it? Stop by poster #1046☕️ #LatinaInSTEM
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Immunology Podcast @immunologypodcast.com · 02/05/2025
Can't make it to #IMMUNOLOGY2025? Brenda and Jason will be recording from Honolulu to keep you up to date!🎙️ Our first daily episode will be released on May 4. Stay tuned! #AAI2025
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Prof. Akiko Iwasaki @virusesimmunity.bsky.social · 02/05/2025
Excited to participate in the 2025 annual American Association of Immunologists meeting in Honolulu 🏝️ Looking forward to seeing my colleagues and learning about the latest advances in immunology. #AAI2025 and #Immunology2025 @aai.org
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Waggoner Lab @labwaggoner.bsky.social · 08/04/2025
ICOS+CD4 T cells define a high susceptibility to anti-PD-1 therapy-induced lung pathogenesis @jci-insight.bsky.social insight.jci.org/articles/vie...
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The American Association of Immunologists @aai.org · 05/04/2025
Heading to #IMMUNOLOGY2025™? Want to maximize your experience? Join our webinar for insider tips on scientific highlights, networking in our new MHC collaboration zones, social events, and more. Register now and ask your questions live: ow.ly/veEt50Vv9Iq. #Immunology
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Nature Microbiology @natmicrobiol.nature.com · 04/04/2025
Out now! Live bacteria can translocate to other tissues via Colonic goblet cell-associated passages which may be beneficial to the host! #MicroSky #MicrobiomeSky 🦠 www.nature.com/articles/s41...
nature.com
Colonic goblet cell-associated antigen passages mediate physiologic and beneficial translocation of live gut bacteria in preweaning mice - Nature Microbiology
Colonic goblet cell-associated passages allow translocation of live bacteria to other organs in early life, potentially leading to beneficial impacts.
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American Physiological Society @apsphysiology.bsky.social · 03/04/2025
#APS2025 starts in three weeks! We're excited to share some programming highlights, including our #NobelLaureate and prestigious award winners who are keynote speakers, and our game-changer sessions. Read more: ow.ly/Re2950VtNTa #WeArePhysiology🧪
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Vini John @vjohn07.bsky.social · 01/04/2025
Super proud of my former lab mate and friend. It’s been amazing to witness this journey from the very beginning to the grand finale hehehe. Thrilled to be a part of it-Congratulations, Sree! ☺️ 🎉🎉🎉 www.nature.com/articles/s41...
nature.com
Colonic goblet cell-associated antigen passages mediate physiologic and beneficial translocation of live gut bacteria in preweaning mice - Nature Microbiology
Colonic goblet cell-associated passages allow translocation of live bacteria to other organs in early life, potentially leading to beneficial impacts.
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Edelblum Lab @edelblumlab.bsky.social · 26/03/2025
📣 New preprint drop! In #ScienceImmunology, we found that regulatory #CD39 γδ IELs are reduced in #IBD, now @saraalonsomera.bsky.social shows that gut #microbiota promote enhanced CD39 expression in γδ IELs through #TCR and IL-15 activation. #gdTcells #GIresearch #Gastrosky @sinaiimmuno.bsky.social
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Edelblum Lab @edelblumlab.bsky.social · 25/03/2025
If you read our #ScienceImmunology paper and want to know how the #microbiota induces #CD39 to promote a #gdTcell #immunoregulatory phenotype, check out our new #preprint!
biorxiv.org
Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling
Intraepithelial lymphocytes expressing the γδ T cell receptor (γδ IEL) provide continuous surveillance of the intestinal epithelium. We report that mice harboring a microbiota-specific hyperproliferat...
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Reposted by Vini John
Waggoner Lab @labwaggoner.bsky.social · 26/03/2025
Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling @edelblumlab.bsky.social doi.org/10.1101/2025...
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Society for Mucosal Immunology @societymucosalimm.bsky.social · 24/03/2025
It's here! Check out the latest Mucosal Immunology Podcast featuring Dr. Cecilia Johansson from Imperial College London, and solve the new Medical Mystery from Ashu Mangalam. 🩺✨ 🎧 Tune in now: socmucimm.org/resources/mu... #MucosalMonday @mucosalimmunol.bsky.social
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Edelblum Lab @edelblumlab.bsky.social · 22/03/2025
#Bluetorial: In our latest paper on #gdTcells and #IBD in #ScienceImmunology we found that γδ IEL number and regulatory function are severely compromised BEFORE ileal inflammation occurs, suggesting that γδ IELs may maintain IEL homeostasis in response to a pro-inflammatory microenvironment. 1/n
media.tenor.com
two men are riding a bicycle with a basket on it .
ALT: two men are riding a bicycle with a basket on it .
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Waggoner Lab @labwaggoner.bsky.social · 21/03/2025
Multiple layers of γδ IEL dysregulation and loss of their immunosuppressive capacity occur before the onset of chronic ileitis www.science.org/doi/10.1126/... @nbgolovchenko.bsky.social @sciimmunology.bsky.social @edelblumlab.bsky.social
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Vini John @vjohn07.bsky.social · 22/03/2025
Very interesting study on gdT cells
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The American Association of Immunologists @aai.org · 19/03/2025
Registration is open for the 2025 AAI Immunology Courses! 🔬 Enhance your knowledge from introductory to advanced. ➡️ Introductory (UCLA): July 8-13. ➡️ Advanced (Boston): July 27-Aug 1. Learn from leading experts! Register now: ow.ly/ACr850VkUm9 #Immunology #AAIcourses
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