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Nick Collins

@nick-collins11.bsky.social
476 followers 370 following 15 posts

Assistant Professor at Weill Cornell Medicine studying the impact of diet and the microbiota on our immune system

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Reposted by Nick Collins
Eduardo Gushiken-Ibañez @egi92.bsky.social · 19/06/2026
After several years of work, I'm happy to share that the main project from my PhD is now published in Nature Microbiology. We show that the skin commensal Malassezia produces tryptophan-derived indoles that activate AhR promoting skin barrier function and tissue homeostasis. doi.org/10.1038/s415...
doi.org
Commensal yeast Malassezia produces tryptophan metabolites to promote tissue homeostasis via the aryl hydrocarbon receptor in mice - Nature Microbiology
A ubiquitous skin fungus, frequently associated with skin pathology, is important for maintenance of the skin barrier function through tryptophan derivatives that act as aryl hydrocarbon receptor agon...
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Nick Collins @nick-collins11.bsky.social · 10/02/2026
Also, we're hiring Postdocs and Techs - please reach out if interested!
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Nick Collins @nick-collins11.bsky.social · 10/02/2026
A great collaboration that came out a few weeks ago with the labs of CJ Guo and David Artis - led by Shanshan Qiao from the Guo lab.
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Nick Collins @nick-collins11.bsky.social · 10/02/2026
Our new paper about how the immune system is rewired when food availability is reduced! An awesome team effort by Luisa Menezes Silva, Mingeum Jeong and @seongji1.bsky.social.
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Reposted by Nick Collins
Michael G. Constantinides @mikerobe.bsky.social · 09/05/2025
Our work co-led by @scripps.edu students Dominic & Jonathan shows that microbial tropism determines how metabolites are presented to #MAIT cells!
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Reposted by Nick Collins
Tania Wong @taniawong.bsky.social · 19/04/2025
Excited to share our preprint demonstrating how fumarate metabolism by host and pathogen promotes pneumonia! Itaconate synergizes with fumarate, driving staphylococcal adaptation for survival. Check it out!👇 www.biorxiv.org/content/10.1...
biorxiv.org
Regulation of airway fumarate by host and pathogen promotes S. aureus pneumonia
Staphylococcus aureus is a leading cause of healthcare-associated pneumonia, contributing significantly to morbidity and mortality worldwide. As a ubiquitous colonizer of the upper respiratory tract, ...
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Nick Collins @nick-collins11.bsky.social · 18/04/2025
A nice write-up on our recent collaborative study, led by the lab of Chun-Jun Guo at Weill Cornell news.weill.cornell.edu/news/2025/04...
news.weill.cornell.edu
Gut Microbes Release Cancer-fighting Bile Acids that Block Hormone Signals
Bacteria naturally present in the human intestine, known as the gut microbiota, can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking ...
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Nick Collins @nick-collins11.bsky.social · 12/01/2025
We are hiring a research technician! This position will be critical to advance our understanding of how diet and the microbiota can enhance our immune system against infections and cancer. If you are interested, please reach out for more information!
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