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Vitor Lopes dos Santos

@vitorlds.bsky.social
115 followers 117 following 26 posts
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Vitor Lopes dos Santos @vitorlds.bsky.social · 04/10/2026
US Meddling in Brazil May Decide Latin America’s Future share.google/zGQPHvqAbj56...
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US Meddling in Brazil May Decide Latin America’s Future
Brazil’s presidential election is on a knife-edge. Right-winger Flávio Bolsonaro has powerful interests on his side but is also counting on the Trump administration’s help to push him over the line.
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Jake Watson @jakefwatson.bsky.social · 25/09/2026
Interesting to chat with Lluís Amiguet for today’s ‘La Contra‘ in @lavanguardia.com! Gracias!
lavanguardia.com
Jake Watson, neurocientífico: “Estudiar cerebros de ratón no te descubre todo sobre los humanos”
Tengo 34 años: me quedan muchos para lograr algo en ciencia, pero nunca se sabe. Soy de las islas Orcadas: piérdase allí en mayo. Tengo pareja barcelonesa. Espero hallar en cerebros vivos humanos lo q...
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Helen Barron @helencbarron.bsky.social · 28/07/2026
***New preprint from the lab*** showing “Generative replay across hippocampal-neocortical circuits”. In sleep we show spiking sequences in V1 (sensory neocortex!) that represent information that has not been directly experienced www.biorxiv.org/content/10.6... @bndu.ox.ac.uk @ndcnoxford.bsky.social
biorxiv.org
Generative replay across hippocampal-neocortical circuits
To make flexible decisions, the brain needs to make inferences between events that were not directly experienced together. In sharp-wave ripple (SWR) events, during periods of rest and sleep, spiking ...
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Vitor Lopes dos Santos @vitorlds.bsky.social · 03/04/2026
Very happy to see it out! Congrats!!
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Vitor Lopes dos Santos @vitorlds.bsky.social · 03/04/2026
Cool! Can't wait to read it
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Gabrielle Girardeau @ggirardeau.bsky.social · 01/04/2026
Our paper is out today!!! (not an April fool's day joke) Congrats to authors @azulsilva.bsky.social, @belalima-paiva.bsky.social, Ele Pronier, and mostly to the amazing scientist and human being who led this project @facuumm.bsky.social #neuroskyence #hippocampus www.nature.com/articles/s41...
nature.com
Dorsoventral hippocampus neural assemblies reactivate during sleep following an aversive experience - Nature Neuroscience
Synchronization of sharp-wave ripples across the dorsoventral hippocampus during sleep supports coordinated reactivation that represents negative experiences more faithfully than positive ones.
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Nikolas Karalis @nikolaskaralis.bsky.social · 01/03/2026
I’m building a foundational reading list for our lab (systems & circuit neuroscience, compneuro, modeling, neuromodulators, population coding etc.). I’d like to crowdsource recommendations. Which review(s) would you consider mandatory reading for the next generation of researchers?
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 14/02/2026
A learning-evoked slow-oscillatory architecture paces population activity for offline reactivation across the human medial temporal lobe www.biorxiv.org/content/10.64898/20…
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Marco Pompili @mnpompili.bsky.social · 06/12/2025
Cell assemblies are drawing increasing attention in neuroscience, but one could argue that they are just an epiphenomenon. Is the activity of cell assemblies relevant for the brain? The short answer is yes. The long answer is in our paper, now online at PLOS Biology. 🧵👇 1/10 doi.org/10.1371/jour...
doi.org
Adaptive communication between cell assemblies and “reader” neurons shapes flexible brain dynamics
Cell assemblies have been proposed as key units of brain activity, underlying diverse functions, but their basic features are not well understood. This study shows that interactions between cell assem...
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Liset M. de la Prida @lmprida.bsky.social · 07/12/2025
Happy to announce the 2nd Hippocampus Green Meeting 📍 Barcelona, Spain 🗓️ May 11–12, 2026 Organized together with Manu Valero, Lisa Roux and Dan Bendor 🎤 Keynotes: Nachum Ulanovsky & György Buzsáki ‼️ Call for abstracts now open 🔗 hippocampusgreen.net/wp/ #HippocampusGreen
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Vitor Lopes dos Santos @vitorlds.bsky.social · 06/12/2025
youtu.be/o6UdRXloqGc?...
youtu.be
What Billionaire Tech CEOs Get Wrong About The Future, with Adam Becker
YouTube video by StarTalk
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Dan Levenstein @dlevenstein.bsky.social · 23/11/2025
1) This is a great idea. 2) I would be happy to mentor a project like this. If you want to do a project eg at the intersection of Philosophy of Science and NeuroAI, please feel free to reach out to discuss, or just put my name as a suggested mentor!
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Marco Bocchio @marcobocchio.bsky.social · 19/11/2025
Interested in doing a PhD on how #psychedelics (or other psychoactive substances) impact psychological or social processes @durhampsych.bsky.social ? Have a look at the NINE DTP scheme, now open. DM me if interested.
ninedtp.ac.uk
Home - NINE DTP
Welcome to NINE DTP Delivering Doctoral Training in the Social SciencesThe Northern Ireland and North East Doctoral Training Partnership (NINE DTP) is a collaborative enterprise between seven universi...
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Tim Viney @vineytj.bsky.social · 21/11/2025
***Publication alert*** "Pathological tau alters head direction signaling and induces spatial orientation" www.cell.com/cell-reports...
Title page of our paper
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Adrian Duszkiewicz @adrian-du.bsky.social · 20/10/2025
Thrilled to announce I'll be joining the Division of Neuroscience at @manchester.ac.uk as a Lecturer in Feb '26! The DuLab will explore how the brain integrates sensory streams into internal maps 🌐 using the rodent head-direction circuit, the 'neural compass', as a starting point for the journey 🧭
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Juan Facundo Morici @facuumm.bsky.social · 15/10/2025
Spread the word! 🗣️🎙️ Together with @azulsilva.bsky.social and Bluesky-less Magdalena Miranda, supported by @elife.bsky.social, we’re organizing a webinar bringing together people working in science communication and outreach. Please, feel free to share the flyer with anyone who might be interested!
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James Hyman @jamesmhyman.bsky.social · 02/10/2025
This is beautiful work and quite the discovery. This also plays nicely with the idea that superficial place cells are rigid and deep are flexible. Seems to suggest that the flexibility is more about past rep's integrating with newer rep's, than the opposite.
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The New Yorker @newyorker.com · 01/10/2025
The naturalist Jane Goodall died today at 91. Hope, she argued, is not merely “passive wishful thinking” but a “crucial survival trait.” Revisit a conversation with Goodall, from 2021: nyer.cm/F55JtsS
An image of Jane Goodall and a chimpanzee, from 1965. Photo courtesy CBS Photo Archive / Getty.
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Manfredi Castelli @manfredic.bsky.social · 02/10/2025
I’m pleased to share our new paper, “Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain”, out in @cp-neuron.bsky.social ! With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics
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Mari Sosa @marisosa.bsky.social · 22/09/2025
The Sosa Lab website is now live! www.sosaneurolab.com We will be seeking a postdoctoral researcher to join the growing team! If you are a rodent neuroscientist and interested in doing systems neuro work in the mountains 🏔️, please check out the "Join" page.
sosaneurolab.com
Sosa Lab
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Abhilasha Joshi, PhD @rhythmicspikes.bsky.social · 17/09/2025
1/ 🚨 New preprint! 🚨 Excited and proud (& a little nervous 😅) to share our latest work on the importance of #theta-timescale spiking during #locomotion in #learning. If you care about how organisms learn, buckle up. 🧵👇 📄 www.biorxiv.org/content/10.1... 💻 code + data 🔗 below 🤩 #neuroskyence
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Liset M. de la Prida @lmprida.bsky.social · 04/09/2025
Proud to take on this challenge: building the new Centro de Neurociencias Cajal @institutocajal.bsky.social into a space where neuroscience crosses boundaries and transforms how we understand the 🧠!!
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Vinny Costa @vincentcostaphd.bsky.social · 13/07/2025
Going to open an escape room where hippocampus researchers have to solve riddles without using space as an explanation for everything
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Matteo Guardamagna @matteoguardamagna.bsky.social · 12/07/2025
Our collaboration - from PhD work - examining input-specific (EC L3) contributions to rate and temporal coding in CA1 place cells is now out in @natcomms.nature.com 🔬🧠 rdcu.be/evWtz
rdcu.be
Direct entorhinal control of CA1 temporal coding
Nature Communications - Temporal coding in the hippocampus is thought to be key for memory and predictions. Here, the authors show that blocking one entorhinal input affects two aspects of...
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Dan Levenstein @dlevenstein.bsky.social · 02/07/2025
I know it’s popular to think of citations as attribution of credit, but a part of me also likes to think of them as a trail of fun breadcrumbs for someone 20 years in the future.
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Mike Eliason @holz-bau.bsky.social · 23/06/2025
this heat map study of gender differences of walking through urban environments at night is not surprising, but still sort of incredible to see news.byu.edu/intellect/st...
news.byu.edu
Study visually captures hard truth: Walking home at night is not the same for women
An eye-catching new BYU study shows just how different the experience of walking home at night is for women versus men.
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Athena Akrami @athenaakrami.bsky.social · 18/06/2025
It's so heartbreaking to see one of the 'three angry old men'* flirting w the idea of bombing a country so nonchalantly. Like 90million ppl are at the mercy of the 'noise' in his drift diffusion process--is it accumulating to this bound or that bound😞 *see this: www.theguardian.com/commentisfre...
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Mari Sosa @marisosa.bsky.social · 12/06/2025
It's officially published!! In my main postdoc work with @markplitt.bsky.social and @lgiocomo.bsky.social, we found that the hippocampus simultaneously encodes an animal's spatial position and its experience relative to reward in parallel population codes. 🧵 www.nature.com/articles/s41...
nature.com
A flexible hippocampal population code for experience relative to reward - Nature Neuroscience
Sosa et al. find that hippocampal neural activity in mice encodes both environmental location and experience relative to rewards, spanning distances far from reward, through parallel and flexible popu...
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Hannah Payne @hannahpayne.bsky.social · 11/06/2025
My latest Aronov lab paper is now published @Nature! When a chickadee looks at a distant location, the same place cells activate as if it were actually there 👁️ The hippocampus encodes where the bird is looking, AND what it expects to see next -- enabling spatial reasoning from afar bit.ly/3HvWSum
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Vitor Lopes dos Santos @vitorlds.bsky.social · 07/06/2025
Thank you Sanja!
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Vitor Lopes dos Santos @vitorlds.bsky.social · 06/06/2025
The embedding enables a cool experiment: start with a tetrode in CA1 pyr, lower it gradually, and project the signal at each step. The tetrode follows the predicted path, and the gamma profiles match the silicon probe data beautifully at each step. See one going from CA1 pyr to DG midmol below!
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Vitor Lopes dos Santos @vitorlds.bsky.social · 05/06/2025
If you're interested in the code, see: github.com/vitorlds/Hip... I’ll be updating it soon with a newer Python version and more data! (13/13)
github.com
GitHub - vitorlds/Hipp-LFP-embedding: Code for Lopes-dos-Santos et al. (2025) Cell Reports
Code for Lopes-dos-Santos et al. (2025) Cell Reports - vitorlds/Hipp-LFP-embedding
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Vitor Lopes dos Santos @vitorlds.bsky.social · 05/06/2025
Overall, I had a lot of fun preparing this manuscript. It started as a side project to support various experiments in the lab, but it grew into its own thing. Huge thanks to Demi and David for working with me on this at @mrcbndu.ox.ac.uk, and to our reviewers for helping improve the paper. (12/13)
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Vitor Lopes dos Santos @vitorlds.bsky.social · 05/06/2025
In short: LFPs carry rich circuit information. We mapped oscillations and neuronal firing across CA1–DG layers. This opens new doors for identifying oscillations, circuit motifs, and homogenize layer identification across datasets. Check out the paper: doi.org/10.1016/j.ce... (11/13)
doi.org
Redirecting
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Vitor Lopes dos Santos @vitorlds.bsky.social · 05/06/2025
Using optogenetics, we tested how CA1 interneurons across layers respond to upstream input. CA3 terminal stimulation strongly activated pyramidale (PyrInt) and radiatum (rad) interneurons, while EC terminal stimulation strongly drove LM interneurons. (10/13)
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Vitor Lopes dos Santos @vitorlds.bsky.social · 05/06/2025
Using embedding-guided tetrodes, Demi recorded interneurons in sparse CA1 layers: rad and LM (btw great dataset, stay tuned for future work on this!). Firing behavior was layer-specific; e.g., LM interneurons were barely active in ripples. Preferred theta phase also varied across layers. (9/13)
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Vitor Lopes dos Santos @vitorlds.bsky.social · 05/06/2025
I love this figure By projecting tetrode LFPs from several mice onto the embedding (estimating each tetrode’s “depth”), we recover gradually changing theta and ripple waveforms, as if recorded with a single linear probe. No need for alignment or histology. Just the signals and the embedding. (8/13)
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Vitor Lopes dos Santos @vitorlds.bsky.social · 05/06/2025
Zooming in, the embedding also separates deep vs superficial CA1 pyramidal cells. These groups differ in firing rates (awake and sleep), theta modulation, and coupling to gamma and ripple. This let us replicate findings from fancy silicon probes using tetrodes, and extend them further. (7/13)
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Vitor Lopes dos Santos @vitorlds.bsky.social · 05/06/2025
From our spike analysis: In pyr fast gamma, principal cells fire before interneurons. In rad fast gamma, this flips! Same freq range, but ≠ mechanism. + pyr fast gamma and ripples may arise from the same oscillator: called 'fast gamma' when theta-driven, 'ripples' when driven by SW inputs. (6/13)
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Vitor Lopes dos Santos @vitorlds.bsky.social · 05/06/2025
Histological validation: lower tetrodes along the CA1–DG axis until they reach a target layer, then confirm final position with histology. It’s really robust! Ephys patterns do predict anatomical layers. See two tetrodes going to DG molecular layer below (more examples in the paper!). (5/13)
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Vitor Lopes dos Santos @vitorlds.bsky.social · 05/06/2025
We characterize multiple coexisting gamma rhythms organized anatomically and by theta phase. This spatiotemporal structure was robust across mice in our silicon probe dataset. See examples below and check the paper for all the details (including a few novel gamma rhythms)! (3/13)
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Vitor Lopes dos Santos @vitorlds.bsky.social · 05/06/2025
We start by building an embedding that transforms LFP signals (theta and SWR features) from a single channel into a 2D coordinate, which predicts its anatomical layer along the CA1–DG axis. In essence, the embedding links anatomical position to electrophysiological features. (2/13)
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Vitor Lopes dos Santos @vitorlds.bsky.social · 05/06/2025
I'm pleased to share our new work, “Spatio-temporal organization of network activity patterns in the hippocampus”, out in @cp-cellreports.bsky.social ! With Demi Brizee & David Dupret, we track how oscillations and spiking behaviour map onto hippocampal layers using an LFP-based embedding. (1/13)
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Marco Bocchio @marcobocchio.bsky.social · 28/05/2025
🧠🍄Have you used classic or non-classic #psychedelics? We are running an anonymous online study on how these experiences relate to mental processes. Share your experience (takes less than 15 min):👉 durhamuniversity.qualtrics.com/jfe/form/SV_...
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Emily A. Aery Jones @emilyaeryjones.bsky.social · 23/05/2025
I'm hiring a lab tech! If you know any talented college seniors or recent grads who'd enjoy doing cool neuroscience in Baltimore, please encourage them to consider applying: umb.taleo.net/careersectio...
umb.taleo.net
Laboratory Research Assistant (Contractual)
Click the link provided to see the complete job description.
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George Currie @georgealfredcurrie.bsky.social · 19/05/2025
Does publishing serve science or is science serving publishing? Damian Pattinson and I (@elife.bsky.social) argue scientific publishing has evolved into a system that, rather than facilitate scholarly communication, distorts and dictates it. onlinelibrary.wiley.com/doi/10.1002/... #OpenScience
Screenshot of article summary of: Toward Science-Led Publishing
by Damian Pattinson, George Currie

published as an opinion piece, in Learned Publishing

Summary

The current dynamic of scholarly publishing prioritises the wants of the publishing industry over the needs of the research community.

This article explores this theme through the lens of ‘publisher-led science’ as a description of our current status quo, and through ‘science-led publishing’ as an improved future state.

We argue that financial motivations central to most publishing distort how research is presented, how it is assessed and even what research is undertaken, leading to a system that hinders, rather than facilitates, scientific progress.

We propose three elements of a science-led publishing approach that would accelerate research communication, incentivise collaboration between authors, editors and reviewers, and create a more transparent and equitable research landscape.

We believe that research funding and research assessment are two of the primary levers for wider change in research and research culture and consider the future purpose of scholarly publishing in a world where these proposals have been widely adopted.
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Nosrat Mohammadi @nosrat.bsky.social · 16/05/2025
I made this figure panel size guide to avoid thinking about dimensions every time. Apparently this post is going to be a 🧵! So feel free to bookmark it and save some time of yours.
A scientific figure blueprint guide!If this seems empty it's bcz I don't plan to use it anytime soon!
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Mohamady El-Gaby @melgaby.bsky.social · 09/05/2025
This is not to be missed. You’ll spend your day trying to make RNNs psychotic. And we’ll pay you for it!
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Abhilasha Joshi, PhD @rhythmicspikes.bsky.social · 14/04/2025
Talk 17: @smikulovic.bsky.social talking about how he work led in her lab about neural mechanisms underlying #helping in mice. Such a unique research direction. looking forward to her talk. 🤓
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