iiinova — where your digital self keeps evolving

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Carl T. Bergstrom @carlbergstrom.com · 03/10/2026

I have absolutely wondered about this. Amazing.

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Patrick McHale @patrickmchale.bsky.social · 18/12/2025

if you haven't played julia's OTGW game, it's over there!

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Sean Marshall @seanyyz.bsky.social · 14/07/2026

Why I’m a fan of the Oxford comma.

TORONTO STAR
BOOK REVIEW
Sylvia Plath, a New York vigilante and Shah of Iran featured in latest historical fiction

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lauren @lauren.rotatingsandwiches.com · 17/05/2026

if i was going to give a college commencement speech i would make sure to start with something the students could rally behind. something like "we will mechanically suck the youth from your bones to feed a mechanical eschaton, which my generation will use to climb heaven and become new gods"

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rax ‘levon honkers’ king @raxkingisdead.bsky.social · 11/03/2026

rebecca solnit today rebecca solnit tomorrow rebecca solnit forever

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Ben Collins @bencollins.bsky.social · 18/02/2026

A post so smart I'm almost afraid to share it. www.garbageday.email/p/the-only-t...

The question of our time is how do you artistically rebel — and win — against a totally flat cultural landscape? And before my readers, who I assume are all approximately 36 years old and very tired, say, “so what, who cares?” This does matter. I mean, just look around right now lol. You know things are bad when even OpenAI President Greg Brockman is posting stuff, like “Taste is a new core skill.” If people had taste, your company wouldn’t exist, Greg.

But if everything is just attention now, and attention is completely commodified by algorithmic tech platforms, how can you push back against that? Well, I am slowly coming around to a theory on the new cool: You have to essentially pre-deplatform yourself.

Culture right now is determined not by human teams of editors and producers picking and choosing what youth culture gets the spotlight, but, instead, by the unthinking algorithms that power YouTube and TikTok. Which means the only things that have the level of scarcity and danger required to be seen as cool by young people will, slowly, but surely, be whatever is unacceptable on those platforms.

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Philip Gourevitch @pgourevitch.bsky.social · 18/02/2026

notorious radical left communist rag says tax the rich

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Abdalla Alkhawaja @alkhawaja.bsky.social · 20/01/2026

Excited to share our latest work in @ajhgnews.bsky.social 🧬📄 We mapped the regulatory landscape of human liver at single-nucleus resolution using snMultiome, connecting genetic variants to the cell-type mechanisms underlying cardiometabolic disease. www.sciencedirect.com/science/arti...

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Rebecca Solnit @rebeccasolnit.bsky.social · 08/01/2026

Violence is too often sloppy; it spills over. Misogynists kill a lot of men, racists kill white people, ICE in its attacks on immigrants and anyone who looks like them just killed a white US citizen. When you're a hammer, everything looks like a nail; when you're a gun everyone is a target.

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Chris Evans @muc5bio.bsky.social · 02/12/2025

This is an important and information rich article. I wondered about the effects by Institute. The table below (which is snipped here but is in the article) has that info. Broken down by # of grants and $ amounts.

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Emily C. Hughes @emilyhughes.bsky.social · 09/11/2025

pre-writing a devastating obituary for your enemy is god-tier hating of a kind you don’t often see anymore. renaissance haterism. beautiful stuff.

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Jeremy Berg @jeremymberg.bsky.social · 08/11/2025

Bluetorial-Jim Watson I met Jim Watson a few times but did not know him well. However, I was greatly influenced by his book “The Double Helix”. He was a complicated human being with some very, very bad features, but some good contributions. What follows is my personal perspective. 1/41

media.tenor.com

a cartoon says hey everybody an old man 's talking while bart simpson looks on

ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on

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Michel Nivard @michelnivard.bsky.social · 28/11/2024

🚨 This will become a curated list of awesome tools for complex trait genetics, **add yours**! it may become a review in which case those who contribute are invited as co-authors.

github.com

GitHub - MichelNivard/awesome-complex-trait-genetics: A list of awesome tools for complex trait genetics.

A list of awesome tools for complex trait genetics. - MichelNivard/awesome-complex-trait-genetics

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Dr. Lisa Corrigan @drlisacorrigan.bsky.social · 19/10/2025

In social movement studies, we talk about how marches and protests expand the threshold of acceptable risk so that people take more and bigger social risks IN PUBLIC, EN MASSE. This is extremely important for the bourgeois white folks holding signs and building social rapport.

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Graham Coop @gcbias.bsky.social · 15/10/2025

We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT

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Val Gartner @vgartner.bsky.social · 30/09/2025

Just pre-ordered it! Looking forward to reading it!

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Simon Fisher @profsimonfisher.bsky.social · 07/08/2025

If someone you know buys into claims about "genetic optimization" of embryos using polygenic scores of cognition, just send them our 2024 paper on Beethoven & musicality. We wrote it to help communicate limits of individual-level genetic predictions & complexity of links between DNA & behaviour. 🧪👇

cell.com

Notes from Beethoven’s genome

Wesseldijk et al. compare the genomic information collected from Ludwig van Beethoven with population-based datasets used to quantify musical achievement.

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Carl T. Bergstrom @carlbergstrom.com · 16/07/2025

1. Kevin Gross and I just posted a new science-of-science preprint. This one explores the looming peer review crisis. As many of you know, it's becoming significantly more difficult for journal editors to find scholars willing to serve as peer reviewers for submitted manuscripts.

arxiv.org

Will anyone review this paper? Screening, sorting, and the feedback cycles that imperil peer review

Scholarly publishing relies on peer review to identify the best science. Yet finding willing and qualified reviewers to evaluate manuscripts has become an increasingly challenging task, possibly even ...

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Katie Mack @astrokatie.com · 26/06/2025

The maddening thing is that this would have been PAINFULLY OBVIOUS if they had ANY EXPERIENCE AT ALL working with the government! In any way! Or if they had asked a single question!! 😖

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Evolutionary Ecology Group, Cambridge @eegcam.bsky.social · 20/06/2025

We are excited to announce that tidypopgen – a new package for rapid population genetic workflows in R – is now available at evolecolgroup.github.io/tidypopgen/ 🧬💻 Read more in the preprint describing its features here: www.biorxiv.org/content/10.1... #popgen #Rpackage #genetics 1/2

evolecolgroup.github.io

Tidy Population Genetics

We provide a tidy grammar of population genetics, facilitating the manipulation and analysis of data on biallelic single nucleotide polymorphisms (SNPs). `tidypopgen` scales to very large genetic data...

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Yoav Gilad @ygilad.bsky.social · 10/06/2025

People always stop me in the street to ask: "Yoav, where are the disease-associated eQLTs? We found a lot in GTEx but we can't find anymore. Do you know where they are?" (For the record, no one has ever asked me this, but it is a really good question!) I think we know where they are.

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Peter Gleick @petergleick.bsky.social · 31/05/2025

There are 2 previous historical cases of countries destroying their science and universities, crippling them for decades: Lysenkoism in the USSR and Nazi Germany. The Trump administration will be the 3rd. It's not just budgets but research, institutions, expertise, and training the next generation.

Graphs showing 25 years of budgets for the National Institute of Health, NASA, and the NSF. In all cases, the proposed budget for next year is far, far below any year of the previous quarter century.

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Alondra Nelson @alondra.bsky.social · 13/05/2025

"For me, the answer now lies in refusal, the withdrawal of participation from systems that require dishonesty as the price of belonging." Today I am resigning from the National Science Board and the Library of Congress Scholars Council. I wrote about my decision in TIME. time.com/7285045/resi...

time.com

Why I’m Resigning from the NSF and Library of Congress

I cannot participate in systems that require dishonesty as the price of belonging.

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Ellen Leffler @ellenleffler.bsky.social · 28/04/2025

Postdocs: Human Genetics at Utah will be hosting our annual Rising Stars in Genetics and Genomics Symposium in Sept. Apply here: shorturl.at/wBMg2 There will be sessions on developmental, evolutionary and disease genetics. A chance be invited to SLC to network here and with peers! Please share.

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Jeremy Berg @jeremymberg.bsky.social · 23/04/2025

ACTION ITEM-----ACTION ITEM Implementation of Schedule F This is what a lot of us have been worried about. This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs. BUT THERE IS A COMMENT PERIOD... 1/n

media.tenor.com

the word alert is in a purple circle

ALT: the word alert is in a purple circle

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Cara Pelletier @scaradactyl.bsky.social · 17/04/2025

Hi, I’m autistic and I’m the mayor of my city.

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Michael Love @mikelove.bsky.social · 17/04/2025

My list of interesting, new packages in Bioconductor 3.21: bedbaser - A client for BEDbase. bedbaser provides access to the API. It also includes convenience functions to import BED files into GRanges objects and BEDsets into GRangesLists. bioconductor.org/packages/bed... BEDbase url: bedbase.org

bioconductor.org

bedbaser

A client for BEDbase. bedbaser provides access to the API at api.bedbase.org. It also includes convenience functions to import BED files into GRanges objects and BEDsets into GRangesLists.

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Julia Angwin @juliaangwin.com · 12/04/2025

Courage is contagious. But how do we catch it? For months, @amifieldsmeyer.bsky.social and I have been asking dissidents and activists from around the world how we can topple authoritarianism. We assembled their lessons into a field guide to courage. www.newyorker.com/news/the-wee...

newyorker.com

So You Want to Be a Dissident?

A practical guide to courage in Trump’s age of fear.

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Andrew Simon @simongandrew.bsky.social · 29/03/2025

One of many moments in Omar El Akkad’s new book, “One Day, Everyone Will Have Always Been Against This,” that will stop you in your tracks.

There is an impulse in moments like this to appeal to self-interest. To say: These horrors you are allowing to happen, they will come to your doorstep one day; to repeat the famous phrase about who they came for first and who they'll come for next. But this appeal cannot, in matter of fact, work. If the people well served by a system that condones such butchery ever truly believed the same butchery could one day be inflicted on them, they'd tear the system down tomorrow. And anyway, by the time such a thing happens, the rest of us will already be dead.
No, there is no terrible thing coming for you in some distant future, but know that a terrible thing is happening to you now. You are being asked to kill off a part of you that would otherwise scream in opposition to injustice. You are being asked to dismantle the machinery of a functioning conscience.
Who cares if diplomatic expediency prefers you shrug away the sight of dismembered children? Who cares if great distance from the bloodstained middle allows obliviousness. Forget pity, forget even the dead if you must, but at least fight against the theft of your soul.

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no brain, only alison @alisonborealis.bsky.social · 25/03/2025

33% increase in Texas maternal mortality. Holy shit.

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Aidan Quinn @aidoq.bsky.social · 17/03/2025

Actuarial studies aren’t going to convince anyone who wants to defund the #NIH but in terms of ROI that seems like a pretty solid multiple, not to mention the benefits to life and health! 🧪

news.harvard.edu

NIH funding delivers exponential economic returns — Harvard Gazette

Report finds all 50 states reap gains in patient health, job creation, research resources, business development.

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FragileNucleosome @fnucleosome.bsky.social · 10/03/2025

🥁We are just 3 days away from our next #FragileNucleosome seminar! We are delighted to host, 2 amazing ECR researchers @rachelhoffman.bsky.social & @jonmarkert.bsky.social this Wed! PS1: Don't forget that US has switched to PDT PS2: The recurring registration link: us06web.zoom.us/webinar/regi...

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Hank Green @hankgreen.bsky.social · 02/03/2025

We are experiencing an assault on science unparalleled by anything I’ve seen in my life. It’s not one issue or another anymore, the entire institution is under attack by the most powerful individuals in the country. This Friday, where will you be? standupforscience2025.org

standupforscience2025.org

STAND UP FOR SCIENCE

March 7, 2025. Washington DC and nationwide. Because science is for everyone.

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Eric Topol @erictopol.bsky.social · 01/03/2025

Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter www.nytimes.com/2025/03/01/u...

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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 27/02/2025

Very sad to see that #RareDiseaseDay event at FDA-NIH has been cancelled. Cuts that limit rare disease research and cures (1) leave patients behind, and (2) forfeit precious opportunity to learn more about common human diseases. udnf.org/udnf-stateme...

udnf.org

Statement on Rare Disease Day, Research and Funding - UDNF

UDNF Statement on Rare Disease Day 2025 Cancellation, Research Funding, and Policy Impacts on the Ultra-Rare and Undiagnosed Community

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Eric Topol @erictopol.bsky.social · 03/02/2025

An update with latest data available for graph of life expectancy vs health care expenditures per capita for 20 countries and one outlier.

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Harmit Singh Malik @harmitmalik.bsky.social · 28/01/2025

If you have been affected by the fires in LA, or are concerned about your ability to keep precious Drosophila strains going during the latest funding crisis, we will host your strains as a backup. Please email me. Please amplify. If you are also able to host fly strains, add your name as well.

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Jonathan Lambert @jonlambert.bsky.social · 28/01/2025

Scientists -- I'm looking to talk to researchers about how all this uncertainty around paused grant reviews and a potentially massive freeze on federal funding is affecting you and your research plans. DM, email or reach out on signal.

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Molly Przeworski @mollyprz.bsky.social · 05/12/2024

Most of the talks from our Oct meeting are now online, with a few more to come: www.precisionmedicine.columbia.edu/videos

precisionmedicine.columbia.edu

Video Library | Precision Medicine

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Dr. Kat Napaaqtuk❄️ @napaaqtuk.bsky.social · 12/12/2024

Saw this on Facebook, of all places. Good advice on how to take steps to make sure your treatments are covered by insurance. Thank you @rahaeli.bsky.social for this thread.

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Alison Mudditt @amudditt.bsky.social · 10/12/2024

Thrilled to share news of a generous $3.3M grant from the Bill & Melinda Gates Foundation to support PLOS's commitment to pioneer a shift away from traditional publishing models and APCs - learn more about our plans below. theplosblog.plos.org/2024/12/plos...

theplosblog.plos.org

PLOS receives $3.3M grant to support Open Access publishing & business model transformation - The Official PLOS Blog

Note: PLOS issued the following press release on Tuesday, December 10. PLOS has been awarded a $3.3million grant from the Bill &amp…

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Mark Peifer (He, him) @peiferlabunc.bsky.social · 11/12/2024

"All four of these patients had undergone stem cell transplants for their blood cancer treatment. Their donors also had the same HIV-resistant mutation that deletes a protein called CCR5, which HIV normally uses to enter the cell."

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Stephen Turner @stephenturner.us · 09/12/2024

Spread-gl: visualising pathogen dispersal in a high-performance browser application academic.oup.com/bioinformatics/adv… 🧬🖥️🧪 github.com/GuyBaele/SpreadGL

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Stephen Turner @stephenturner.us · 05/12/2024

📍Pinned Post: Welcome to the papers with code feed! bsky.app/profile/did:... Papers from PubMed, bioRxiv, Bature, PLoS, etc, with links to GitHub will be included here. Anyone can post to this feed. See also: blog.stephenturner.us

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Chen-Yang Su, PhD @chenyangsu.bsky.social · 17/11/2024

I thought it could be nice to connect the community of researchers in human genetics, so here is the Genetics Starter Pack! 🧬 #academicsky Let me know if you would like to be added or know someone to add. Enjoy and share! go.bsky.app/LN2NRuB

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Eric Topol @erictopol.bsky.social · 20/11/2024

A big day of output for the Human Cell Atlas, a global collaborative project with 100 countries to understand our ~37 trillion cells A Wikipedia of our cells, a "remarkable achievement" nature.com/articles/d41... nature.com/immersive/d4...

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Eric Topol @erictopol.bsky.social · 18/11/2024

A mechanism for why durable weight loss is so difficult: epigenetic memory of fat cells www.nature.com/articles/s41...

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John Prensner @johnprensner.bsky.social · 16/11/2024

Wow this is an essential study to read for any genome folks 🧬💻 🧪 #GeneSky

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