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Sean Flynn

@seanflynn.bsky.social
1.1K followers 1.4K following 8 posts

Enhancers and 3D genome structure | Lecturer @uniofexeter.bsky.social | sites.google.com/view/flynnlab/

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Reposted by Sean Flynn
Wyoming Wormboy @wyomingwormboy.bsky.social · 07/09/2026
Still in my dahlia phase. They are just so arresting.
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Reposted by Sean Flynn
Stefan Schoenfelder @stefanschoenfelder.bsky.social · 07/08/2026
Very happy to see this story finally out in @natbiotech.nature.com: www.nature.com/articles/s41... Fantastic collaboration with @lancasterlab.bsky.social on how to identify and ‘fix’ differentiation-compromised human pluripotent stem cells. @babrahaminst.bsky.social @mrclmb.ac.uk 🧵 below
nature.com
Reversible epiblast regionalization determines differentiation potential of human pluripotent stem cells - Nature Biotechnology
The differentiation variability of human pluripotent stem cell lines is diagnosed and corrected.
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Giselle Cheung @giselletycheung.bsky.social · 04/07/2026
So excited to finally meet everyone tomorrow! We have a great program planned for you! ☀️🧠💡🏖️ Neuroscience researchers are stronger together (especially in times of uncertainty)! 💪💪💪 @young-pi-neuro26.bsky.social #FENS2026
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Surfin' NuRD @surfinnurd.bsky.social · 02/04/2026
Do you do a PhD on Chromatin in this cool critter? Work with @jordisolana.bsky.social @seanflynn.bsky.social, Magda Strauss and myself @lsiexeter.bsky.social on developing #singlecell #chromatin analyses to better understand pluripotency #planarians. www.exeter.ac.uk/research/ins...
Image of a planarian, from Wiki.
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Sean Flynn @seanflynn.bsky.social · 06/11/2025
Lots of exciting PhD projects available through @swbiodtp.bsky.social If you are interested in our project using stem cells, CRISPR and genomics, please get in touch. Informal inquiries encouraged Project: www.swbio.ac.uk/files/2025/1...
swbio.ac.uk
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Sean Flynn @seanflynn.bsky.social · 21/10/2025
Exciting postdoc opportunity!
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Reposted by Sean Flynn
Di Antonio Research Group @diantoniogroup.bsky.social · 18/09/2025
We are hiring! We are looking for a PDRA to study the epigenetics of breast cancer dormancy using chemical biology and genomics approaches. This is a 3-year position and is aimed at chemical biologists or biologists. Please share and apply using the link below 👇👇👇 www.imperial.ac.uk/jobs/search-...
imperial.ac.uk
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
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Reposted by Sean Flynn
Surfin' NuRD @surfinnurd.bsky.social · 30/08/2025
Check it out, Chromatin Kids! Chromatin remodeller does stuff to Transcription Factors! Functions where it is seldom seen! Both decreases and increases chromatin accessibility! How cool is that?
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Sean Flynn @seanflynn.bsky.social · 02/09/2025
Please share! PhD projects available through @gw4biomeddtp.bsky.social Please get in touch if you are interested in studying chromatin biology in stem cell models gw4biomed.ac.uk/architects-o... gw4biomed.ac.uk/risk-vs-prot... gw4biomed.ac.uk/rna-dependen... gw4biomed.ac.uk/investigatin...
gw4biomed.ac.uk
Architects of the Genome: Using genomic technologies to elucidate the role of CTCF in neurodevelopmental disorders - GW4 BioMed MRC DTP
Project Code MRCNMH26Ex Flynn Project Type The project is primarily wet-lab based, with a dry-lab component in Years 2 and 3. Research Theme Neuroscience and Mental Health Project Summary Download Sum...
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W. Brent Derry @wbderry.bsky.social · 16/07/2025
Model organism communities are fantastic. Good work, "Drosophilists"! www.nature.com/articles/d41...
nature.com
Giant study finds a research field that’s mostly reproducible
Researchers assessed more than 1,000 results from fruit-fly immunity research published between 1959 and 2011. The majority of findings look verifiable.
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Reposted by Sean Flynn
Krzysztof Herka @kherka.bsky.social · 04/06/2025
How does (local #DNA) structure affect (3D #genome) structure? Can mutating G4s abolish #enhancers key for #blood function? In the second part of our explorations of #G4s in gene regulation, we show how abolishing G-quadruplex structures in the genome disrupts enhancers. 1/9 doi.org/10.1186/s130...
doi.org
DNA G-quadruplex structures act as functional elements in α- and β-globin enhancers - Genome Biology
Background Enhancer elements interact with target genes at a distance to modulate their expression, but the molecular details of enhancer–promoter interaction are incompletely understood. G-quadruplex...
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Pradeepa Madapura @pradeepmadapura.bsky.social · 03/06/2025
Happy to be part of this exciting work. A must-read for enhancer aficionados: A massive effort has gone into generating genome-wide STARRseq in hPSCs and conducting functional validation assays. Congratulations to all authors, Stefan and Ufuk, for leading this project 🎉.
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Reposted by Sean Flynn
Surfin' NuRD @surfinnurd.bsky.social · 08/05/2025
Please get in touch if you want to apply for this to work with me on chromatin remodellers, enhancers and lineage commitment in mammalian stem cells at @lsiexeter.bsky.social
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Clem Bernard @clembrnrd.bsky.social · 25/04/2025
I will soon start recruiting for a Wellcome-funded postdoc position! I’ll be at the #BNA2025 meeting next week. If you like cortical development, wiring, and post-transcriptional regulation, do get in touch and we can have a chat in Liverpool! 😀
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Clem Bernard @clembrnrd.bsky.social · 17/04/2025
Job alert 🚨 We are hiring a research assistant! This 7-year position available @exeter.ac.uk from Sept 2025 will involve keeping the lab running as well as contributing to our research activities on brain development. Full details tinyurl.com/23nyds34. Please spread the word!
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Reposted by Sean Flynn
Yaser Atlasi @yatlasi.bsky.social · 31/03/2025
We have a postdoc position in my group in collaboration with EMBL Rome; join us to make important discoveries in this exciting project. Please apply or share. hrwebapp.qub.ac.uk/tlive_webrec...
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All-Ireland Chromatin Consortium @aicc-ireland.bsky.social · 24/03/2025
We are very excited to launch the registration for our 2025 symposium on 'Chromatin, Epigenetics and Transcription' today! Join us at @tcddublin.bsky.social on May 28th for this event featuring keynote, new PI and PhD/postdoc talks and posters! allirelandchromatinconsortium.ie/annual-meeti...
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Sean Flynn @seanflynn.bsky.social · 03/03/2025
We have a funded PhD position available in Exeter @exeter.ac.uk Gene Regulation in Brain Development and Disease 🧬 Please share / repost www.exeter.ac.uk/study/fundin...
exeter.ac.uk
Award details | Funding and scholarships for students | University of Exeter
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Reposted by Sean Flynn
Inês Barroso @inesbarroso.bsky.social · 16/12/2024
jobs.exeter.ac.uk/hrpr_webrecr... Interested in data management? Want a permanent position working in beautiful Devon and work collaboratively to support the work of lots of genomics team? Apply!!
jobs.exeter.ac.uk
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Sean Flynn @seanflynn.bsky.social · 11/12/2024
Thread below on @robinburns.bsky.social et Al’s new paper #evobio #plantscience 🌱
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Sean Flynn @seanflynn.bsky.social · 22/11/2024
If you are interested in #Epigenetics apply for a PhD with Jack Hardwick and Jonathan Hanley in Bristol, and our group in Exeter. Elucidating the role of DNA modifications in neurons Funded by #SWBio DTP Deadline: Dec 4 To apply: www.swbio.ac.uk/programme/ho...
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Reposted by Sean Flynn
All-Ireland Chromatin Consortium @aicc-ireland.bsky.social · 19/11/2024
Nice to see all you chromatin & epigenetics aficionados here! As we build our network back up please repost details for our upcoming webinar this Friday! We are delighted to welcome Emma Farley for her webinar 'Dependency Grammar of Developmental Enhancers' on November 22nd. Registration below 👇
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Surfin' NuRD @surfinnurd.bsky.social · 07/11/2024
Fully funded #PhD Studentship with myself and JJ Phillips at the Living Systems Institute, @uniofexeter.bsky.social "Control of chromatin remodeller activity to direct cell fate decisions" #Chromatin #Transcription #StemCells #StructuralBiology Please re-skeet! www.exeter.ac.uk/research/ins...
exeter.ac.uk
LSI PhD programme | Living Systems Institute | University of Exeter
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Sean Flynn @seanflynn.bsky.social · 14/11/2024
Welcome @kherka.bsky.social, who is working on chromatin and G4s
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