Nature Communications - Primary sclerosing cholangitis (PSC) is an autoimmune condition affecting the liver. Here, the authors generate an immunobiliary transcriptomic atlas and show that dendritic...

Nature Reviews Gastroenterology & Hepatology, Published online: 07 April 2026; doi:10.1038/s41575-026-01188-7Concerns have been raised as to whether microplastics and nanoplastics (MNPs) influence human health. This Perspective examines the emerging evidence on MNP accumulation in the liver and its potential effects on human liver health and disease. Research gaps and priorities are also addressed.

This two day symposium will highlight cutting edge research in immunity in health and disease.

The microbial metabolite trimethylamine (TMA), the precursor of TMAO, which is associated with adverse cardiometabolic outcomes, is shown to have beneficial metabolic and anti-inflammatory effects in the host in the context of obesity.

The Centre for Predictive in vitro Models (CPM) represents multidisciplinary research focusing on the development and use of predictive in vitro models at Queen Mary University of London. This incorpo...

Mapping of the neutrophil compartment using single-cell transcriptional data from multiple physiological and patological states reveals its organizational architecture and how cell state dynamics and trajectories vary during health, inflammation and cancer.

Nature Reviews Gastroenterology & Hepatology, Published online: 13 October 2025; doi:10.1038/s41575-025-01114-3This Roadmap presents and outlines the creation of the Human Liver Cell Atlas as a reference map and resource for the liver community, providing an overview of the steps needed to build the atlas, as well as outlining the major challenges and potential of this venture.

Applications for 2026 entry will open on Tuesday 7 October 2025 at midday (BST) and close at 23:59 (GMT), Tuesday 18 November 2025.

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

Nature Reviews Gastroenterology & Hepatology, Published online: 22 September 2025; doi:10.1038/s41575-025-01118-zThis Review provides a comprehensive overview of the role of tissue-resident memory CD8+ T cells in hepatic immune responses, explores their dual function in liver immunoprotection and immunopathology, and discusses their therapeutic potential.

Are you an early career researcher interested in the cell or molecular mechanisms underlying disease? Do you have an outstanding record and an innovative research plan?

Cellular & Molecular Immunology - Myeloid cells in chronic liver inflammation

Rapid extracellular antibody profiling reveals a contribution of autoantibodies to the effectiveness of checkpoint immunotherapy for cancer.

Applications are now open for up to five postdoctoral positions in the area of developmental epigenetics.

We are recruiting Programme Leader Track positions focusing on 1) Metabolic Physiology using murine and/or human in vivo models and 2) Immunometabolism.

The MRC Laboratory of Medical Sciences (LMS) is a biomedical research institute where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. LMS...

In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.

Nature - In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.

Nature Reviews Gastroenterology & Hepatology, Published online: 22 May 2025; doi:10.1038/s41575-025-01068-6Hepatic stellate cells (HSCs) are best known as the primary fibrogenic liver cell type. This Review provides a comprehensive overview of protective and pathogenic HSC functions in health and disease and discusses novel therapeutic concepts derived from this dual role.

Severe alcohol-related hepatitis (sAH) is an inflammatory condition with high short-term mortality. Hypothesis-driven approaches have failed to identify effective treatments. Given the role of lipids ...

We are looking for a highly motivated and talented lab technician to join our team at the VIB-UGent Center for Inflammation Research which is focused on understanding the functional heterogeneity of m...

As proof of principle, an analysis using a suite of human-aligned immunocompetent mouse models of hepatocellular carcinoma identifies a promising therapeutic candidate, cladribine, which acts in a highly effective subtype-specific manner in combination with standard-of-care therapy.

Hepatic stellate cells regulate hepatocyte functions via R-spondin 3.

Research Assistant (Computational biology) (Fixed Term) in the Department of Oncology at the University of Cambridge.

Immune responses lie at the heart of almost every aspect of human health, including host responses to infection, autoimmunity, cancer, metabolism and aging. While adaptive immune responses by B and T…

We are looking for a Research Assistant with a background in immunology/neurobiology to join the interdisciplinary laboratory of Dr Fränze Progatzky at the Kennedy Institute.

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

People with chronic liver disease have dramatic changes to the types and functions of bacteria in the gut and mouth, a new study has revealed.