Sensory nerve activity disrupts how immune cells are organised within lung tumours, weakening the immune response.

Castro-Dopico et al. report the design of reagents to bridge F-actin and Fcγ receptors, endowing a range of antigen-presenting cells with the ability to cross-present antigens from dead tumor cells an...

New research has uncovered an unexpected way to stimulate the immune system against cancer: by subtly disrupting how tumour cells manufacture their proteins.

In this interview, Dr. Lim unpacks the evolving role of cell therapies and reveals the gaps between promise and practice that call for fresh thinking.

A major new UK study, led by The Christie NHS Foundation Trust and The University of Manchester, has been launched to help patients with cancer better tolerate cutting-edge immunotherapy treatments li...

A postdoctoral position is available in the laboratory of Sylvain Delaunay to study how diet affects RNA modifications to drive cancer progression.

YouTube video by CRUK Manchester Institute

This study uncovers a surprising role for GCs in triggering CD8+ T cell–dependent tumour control through downregulation of GARP and thus TGF β signalling.

Dr Claus Jorgensen, Group Leader of the Systems Oncology Group, is looking for a Postdoctoral Scientist to join his group. This is a great opportunity for a self-motivated, innovative, meticulous and ...

Critics question the usability of new league tables meant to inform the public and let them exercise choice.

YouTube video by Francis Crick Institute

Summary:. Immunotherapy has revolutionized survival outcomes for many patients diagnosed with cancer. However, biomarkers that can reliably distinguish treatment responders from nonresponders, predict...

A role for vitamin D in immune modulation and in cancer has been suggested. In this work, we report that mice with increased availability of vitamin D display greater immune-dependent resistance to tr...