Intra-tumour heterogeneity (ITH) and cellular plasticity contribute to therapy resistance. Single-cell transcriptomics is the gold standard for assessing ITH, but this approach remains costly and slow...

Intra-tumour heterogeneity (ITH) and cellular plasticity contribute to therapy resistance. Single-cell transcriptomics is the gold standard for assessing ITH, but this approach remains costly and slow...

PROUD I𝟏𝟗 𝐕𝐈𝐁 𝐫𝐞𝐬𝐞𝐚𝐫𝐜𝐡𝐞𝐫𝐬 𝐫𝐞𝐜𝐨𝐠𝐧𝐢𝐳𝐞𝐝 𝐚𝐬 𝐂𝐥𝐚𝐫𝐢𝐯𝐚𝐭𝐞 𝐇𝐢𝐠𝐡𝐥𝐲 𝐂𝐢𝐭𝐞𝐝 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡𝐞𝐫𝐬 𝟐𝟎𝟐𝟓 Yes, you read that right. And we are beyond proud. But what does this actually mean? Every year, Clarivate highlights ...

Nature Cancer - The complex nature of metastasis-initiating cells (MICs) has long hindered our understanding of how cancer spreads and how to prevent it. A study now identifies a potential MIC...

Position summary The Chris Marine lab at the VIB Center for Cancer Biology (https://ccb.sites.vib.be/en) is actively seeking a skilled bioinformatician proficient in analyzing and integrating single-...

In this essay, I will put forth what I see as a major conceptual challenge for biology in the next decade, one that is inspired by Crick’s Central Dogma: understanding information flow in the cell in ...