The neocortex-wide neural activity is organized into distinct networks of areas engaged in different cognitive processes. To elucidate the underlying mechanism of flexible network reconfiguration, we ...

Animals are born with extensive innate behavioral capabilities, which arise from neural circuits encoded in the genome. However, the information ca...

How learning is affected by context is a fundamental question of neuroscience, as the ability to generalize learning to different contexts is necessary for navigating the world. An example of swift co...

How the navigational system of the brain constructs spatial maps that require both rapid changes and representational accuracy is explored.

Neurons in the hippocampus are correlated with different variables, including space, time, sensory cues, rewards, and actions, where the extent of tuning depends on ongoing task demands. However, it r...

Humans are autotelic agents who learn by setting and pursuing their own goals. However, the precise mechanisms guiding human goal selection remain unclear. Learning progress, typically measured as...

Changes in cortical neural ensembles and heightened coupling between the hippocampus and cortex enable the eventual behavioral integration of memories with overlapping sequential information.

The entorhinal cortex (EC) provides the major input to the hippocampus (HPC). Numerous computational models on the EC propose that its grid cells serve as a spatial metric, supporting path integration...

The complexity of natural environments requires highly flexible mechanisms for adaptive processing of single and multiple stimuli. Neuronal oscillations could be an ideal candidate for implementing su...

How cognitive maps of physical and task space interact when executing cognitive tasks is not fully understood. This paper models how the hippocampal-prefrontal circuits solves memory-guided spatial al...

By recording large populations of neurons in behaving monkeys using newly developed silicon probes, we show that intermittent periods of memorandum-specific spiking coexist with synaptic mechanis...

Abstract. Group-level analyses have typically linked behavioral signatures to a constrained set of brain areas. Here, we show that two behavioral metrics—reaction time (RT) and confidence—can be decod...

Russo et al. show that context-specific place cell assemblies support hippocampal integration of past experiences into future plans during goal-directed behavior and propose a biophysical mechanism be...