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Dr. Nicola Smyllie

@nsmyllie.bsky.social
62 followers 74 following 5 posts

Investigator scientist at MRC Laboratory of Molecular Biology Neurobiologist researching the circadian clock of the suprachiasmatic nucleus STEM Ambassador Passion for Science Public Engagement All views are my own

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Reposted by Dr. Nicola Smyllie
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 07/07/2026
In June, LMB scientists teamed up with @bioclocksuk.bsky.social for a chronobiology outreach exhibit at #TheBigBangFair, engaging 3000 teachers and students over 3 days. Read more about their exhibit here: mrclmb.ac.uk/news-events/... #LMBNews #PublicEngagement @nsmyllie.bsky.social
LMB scientistsExhibit with brain models and worksheets
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Reposted by Dr. Nicola Smyllie
MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 01/07/2026
📢 Applications are open for our Science Technology Graduate Programme! We're looking for recent graduates (with no postgraduate degree) to join our Proteomics and Metabolomics facilities. If you're looking to gain experience in research, we'd love to hear from you. 🗓️ Applications close 9 August.
lms.mrc.ac.uk
Science technology graduate programme
Our Graduate Programme develops fresh science graduates into highly sought after technicians.
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Dr. Nicola Smyllie @nsmyllie.bsky.social · 11/06/2026
We had a great time representing @mrclmb.ac.uk and @bioclocksuk.bsky.social at #TheBigBangFair this week, bringing brains and body clocks to primary school students and teachers, with the aim of inspiring the next generation to pursue STEM careers.
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Reposted by Dr. Nicola Smyllie
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 27/02/2026
New #LMBResearch led by @drbatmo.bsky.social in John O’Neill’s group (@cellbiol-mrclmb.bsky.social) has identified the molecular switch decides day or night. Click here to read how the mTOR pathway controls when mammals are active and the role it’s played in evolution: mrclmb.ac.uk/news-events/...
Person on ladder adjusting clock hands against a sky transitioning from day to night.
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Reposted by Dr. Nicola Smyllie
Andrew Beale @drbatmo.bsky.social · 27/02/2026
Since I moved to @mrclmb.bsky.social I’ve been trying to answer this: Why are some mammals active at night and others in the day? Today our answer is out @science.org www.science.org/doi/10.1126/.... If you’re interested in circadian biology, evolution or how timing shapes physiology, take a look
science.org
A cellular basis for the mammalian nocturnal-diurnal switch
Early mammals were nocturnal while dinosaurs dominated the daytime. Mammalian transition to daytime activity accelerated after the Cretaceous-Paleogene extinction, but the underlying mechanisms remain...
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Reposted by Dr. Nicola Smyllie
Louise Hunter @feedbacklou.bsky.social · 10/11/2025
4yr MRC-funded postdoc position investigating circadian mechanisms in cardiometabolic disease, currently available @manchester.ac.uk www.jobs.manchester.ac.uk/Job/JobDetai... Come and join our brilliant Centre for Biological Timing team! @bioclocksuk.bsky.social #chronobiology #circadian #postdoc
jobs.manchester.ac.uk
Research Associate in Circadian Mechanisms in Cardiometabolic Disease:Oxford Road
Due to the nature of the funding, KTP Associates who have already completed a KTP are not eligible to apply.
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Reposted by Dr. Nicola Smyllie
BioClocks UK @bioclocksuk.bsky.social · 11/11/2025
Share you #chronobiology research at the upcoming #ClockClub in Nottingham on the 9th of January 2026. Only a few more days until the 14th Nov abstract submission deadline! Send your abstract here: forms.office.com/e/cQDefteB7S
forms.office.com
Microsoft Forms
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Reposted by Dr. Nicola Smyllie
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 10/11/2025
Considering the LMB for your PhD? We’ve got over 25 projects available, covering a wide array of topics. Check them out here: www2.mrc-lmb.cam.ac.uk/students/int... Apply by 2nd DEC for Autumn 2026 admission.
Join the LMB's PhD programme!
Applications now open for October 2026
Deadline 2nd December 2025
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Reposted by Dr. Nicola Smyllie
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 27/10/2025
The M4S Competition has expanded its reach to Birmingham and Manchester, underscoring the programme's success in sparking scientific curiosity among primary students across the UK #LMBNews www2.mrc-lmb.cam.ac.uk/m4s-expansio... @mcrcnews.bsky.social @uom-dcs.bsky.social @unibirmingham.bsky.social
M4S collage with past winners and in action pictures
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Reposted by Dr. Nicola Smyllie
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 13/10/2025
Join us at @pborostemfest.bsky.social on Oct 18 to test your detective skills in an interactive game, matching what you see under a microscope with different areas of LMB’s science #PSF2025 📍 ARU Peterborough 🕚 11:00 – 16:00 (Quiet time 9.30-11) www.peterboroughstemfestival.co.uk/exhibitors/m...
peterboroughstemfestival.co.uk
MRC Laboratory of Molecular Biology - Beauty is in the detail - Peterborough STEM Festival
Have a go at coding with Peterborough CoderDojo!
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Reposted by Dr. Nicola Smyllie
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 04/09/2025
Want to help inspire future generations of scientists? Are you passionate about #SciComm? We have a Public Engagement and Communications Officer (Maternity Cover) position in the LMB engagement & comms team: www.reed.co.uk/jobs/public-... Closes 21 SEP #SciCommJobs
Images of children and young people taking part in Public Engagement activities
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Reposted by Dr. Nicola Smyllie
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 20/08/2025
We’re looking for a #postdoc to join Michael Hastings’ group, studying diet-induced neuroinflammation in the hypothalamus and its modulation by circadian clock mechanisms, in collaboration with John O'Neill's group. www.nature.com/naturecareer... Closes 08 SEP #ScienceJobs #PostdocJobs
Michael Hastings in a light pink shirt stands with arms crossed in front of scientific research posters filled with charts and graphs.
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Reposted by Dr. Nicola Smyllie
BioClocks UK @bioclocksuk.bsky.social · 11/08/2025
☀️ Summer is a great time to observe biological rhythms in action. Look at the insect life around you - do they come out at a particular time of day? 🐝 If so, you've found their 'temporal niche'! 🔗 Learn more through our factsheets here: www.bioclocks.uk/factsheets #SciComm #Ecology 🧪
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Reposted by Dr. Nicola Smyllie
Nature @nature.com · 30/07/2025
To be successful, policymakers need to consider diverse perspectives go.nature.com/3H7XR3X
go.nature.com
Could bridging science and the arts be the key to better policies?
To be successful, policymakers need to consider diverse perspectives. Here’s how we’re reimagining policy process.
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Reposted by Dr. Nicola Smyllie
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 22/07/2025
Are you creative? Curious? Science-savvy? We have a unique opportunity to join the LMB’s VisLab as a Photographer / Videographer where you’ll help communicate ground-breaking research with dynamic visuals. Apply now: mrc.tal.net/vx/mobile-0/... #CambridgeJobs #PhotographyJobs #ScienceCommunication
We're Hiring!
Science Photographer/Videographer
VisLab, MRC LMB
Bring science to life through stunning visuals.
Apply Today
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Reposted by Dr. Nicola Smyllie
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 17/06/2025
Is the next step of your career at the LMB? Come and find us at the @cambridgebiocampus.bsky.social Campus Jobs and Career Fair this Saturday 21st June at the Cambridge Academy for Science and Technology! More details here: cambridge-biomedical.com/event/cbc-jo...
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Reposted by Dr. Nicola Smyllie
BioClocks UK @bioclocksuk.bsky.social · 16/06/2025
What does the evidence say about beating #jetlag? It depends which way you’re going! Check out our full factsheet on Jetlag here: www.bioclocks.uk/factsheets #chronobiology #scicomm 🧪
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Dr. Nicola Smyllie @nsmyllie.bsky.social · 10/06/2025
Thanks to Michael Brunner for writing this #news&views article for @embojournal.org about our recent research on #circadian clock protein dynamics in the SCN: www.embopress.org/doi/full/10....
embopress.org
CRYing for balance: a repressor lingers through peak circadian transcription | The EMBO Journal
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
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Reposted by Dr. Nicola Smyllie
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 03/06/2025
The LMB is committed to being open & honest about why & how we use animals in our research. Our Biological Services Group provide excellent care to our colonies of rodents – our fantastic animal technicians explain why they work with mice in this video: youtu.be/V7CHmPGjvSo #BOARD25 @eara.eu
youtu.be
Why I Work with Mice in Research - An Animal Technician's Point of View
YouTube video by MRC Laboratory of Molecular Biology
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Dr. Nicola Smyllie @nsmyllie.bsky.social · 25/04/2025
A nice summary about my latest paper, and I got to use this image that I had fun putting together (no AI in sight!)
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Reposted by Dr. Nicola Smyllie
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 25/04/2025
Uncovering the hidden complexity behind the brain’s master clock. New research led by @nsmyllie.bsky.social, in Michael Hastings’s group, reveals that body clock proteins PER2 & CRY1 act more independently than previously thought: www2.mrc-lmb.cam.ac.uk/uncovering-t... #LMBResearch 🧪 🕙 🧠
Artistic representation of the complex dynamics exhibited by “clock proteins” within the brain.
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Reposted by Dr. Nicola Smyllie
Andrew Beale @drbatmo.bsky.social · 24/04/2025
If anyone is interested, I've updated our take on a cellular basis of the mammalian nocturnal-diurnal switch @biorxivpreprint.bsky.social We've refined the paper (for the better, hopefully!) - my fave updates are the results from a collab with Zoonomia (Fig 3) www.biorxiv.org/content/10.1...
biorxiv.org
A cellular basis for the mammalian nocturnal-diurnal switch
Early mammals were nocturnal until the Cretaceous-Paleogene extinction enabled diurnal niche expansion. Diurnality evolved multiple times independently, but the mechanisms driving this shift remain un...
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Dr. Nicola Smyllie @nsmyllie.bsky.social · 24/04/2025
Very pleased to see my latest paper out in @embojournal.org Go check it out!
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Reposted by Dr. Nicola Smyllie
The EMBO Journal @embojournal.org · 22/04/2025
Quantitative measures of clock protein dynamics in the mouse suprachiasmatic nucleus extends the #circadian time-keeping model Michael Hastings, Nicola Smyllie @nsmyllie.bsky.social et al @mrclmb.bsky.social www.embopress.org/doi/full/10....
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Reposted by Dr. Nicola Smyllie
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 04/04/2025
LMB scientists showcased their work at the @cambridgefestival.bsky.social with a hands-on activity about the scale of biology and an artistic piece about body clocks. Read about the event here: www2.mrc-lmb.cam.ac.uk/lmb-highligh... #LMBNews #CamFest @nsmyllie.bsky.social
Girl and woman looking under a microscope in an outreach activity
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Reposted by Dr. Nicola Smyllie
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 22/03/2025
LMB @cambridgefestival.bsky.social engagement team ready to go! Join us at CAST today 11-4 to explore the tiny scale of our research, play our mutant matching game & see @nsmyllie.bsky.social Sci-Art collaboration. More details: www.festival.cam.ac.uk/events/molec...
LMB engagement team group photo
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Reposted by Dr. Nicola Smyllie
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 17/03/2025
Looking for something to do next weekend? Join us at @cambridgefestival.bsky.social We’ll be at CAST from 11AM-4PM on 22nd March Discover how scientists unlock the mysteries of life by studying its constituent parts at vastly different scales More details: www.festival.cam.ac.uk/events/molec...
Fluorescent microscopy image
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Reposted by Dr. Nicola Smyllie
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 17/03/2025
We will also display the sci-art collaboration between the contemporary artist Laura Pearson-Clark and Nicola Smyllie @nsmyllie.bsky.social in the LMB's Neurobiology Division
A scientist looking under a microscope and an artist painting
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Reposted by Dr. Nicola Smyllie
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 03/03/2025
📣 Last week to apply to our work experience placements 🧪🔬 Aimed at local Y12 students from state schools interested in a science career 🗓️ 28/07 – 1/08 Eligibility and selection criteria apply Applications by 09/03 Info: www2.mrc-lmb.cam.ac.uk/students/wor... #STEM #WorkExperience #BiologyCareers
Collage showing students in lab based work experience placements
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Reposted by Dr. Nicola Smyllie
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 13/02/2025
📣 Applications are open for our work experience placements 🧪🔬 Aimed at local Y12 students from state schools interested in a science career 🗓️ 28/07 – 1/08 Eligibility and selection criteria apply Applications by 09/03 www2.mrc-lmb.cam.ac.uk/students/wor... #STEM #WorkExperience #BiologyCareers
Collage showing work experience students working in labs
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Reposted by Dr. Nicola Smyllie
Royal Microscopical Society @royalmicrosoc.bsky.social · 11/02/2025
This #WomenInScience Day, why not check out our 'Equity in Microscopy' Resource, which highlights women and other underrepresented people in #microscopy and #cytometry A great resource for conference organisers! Find out more and add to our database: www.rms.org.uk/community/eq...
Woman looking into a microscope, wearing blue, protective gloves and a white lab coat.
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Reposted by Dr. Nicola Smyllie
REVERSED-INEQUALITIES @revers-ed.bsky.social · 11/02/2025
We work today and everyday for the right of every women and girls to be who they want to be. From REVERS-ED we are working to achieve this right from education, so educational inequalities won't be a barrier for any #internationaldayofwomenandgirlsinscience
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Reposted by Dr. Nicola Smyllie
EMBL Events @events.embl.org · 11/02/2025
Happy International Day of Women and Girls in Science 🔬👩‍🔬 🎉 A big thank you to the fantastic scientists we get to work with every day as well as our enthusiastic event participants! Let's continue to break down barriers and advance equality in science 💪 📸 Kinga Lubowiecka/ EMBL
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Reposted by Dr. Nicola Smyllie
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 23/01/2025
The LMB Rising Talent Fellowship for Black heritage scientists is open for applicants! With this 3 year postdoc position we want to enable scientists of Black heritage to learn & grow their experience. To apply and for full details check here: www2.mrc-lmb.cam.ac.uk/recruitment/...  Please share!
Apply now!
LMB Rising Talent Fellowship
3-year postdoctoral fellowship for Black heritage scientists
Visit www.mrc-lmb.cam.ac.uk for more information
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Reposted by Dr. Nicola Smyllie
BioImagingUK @bioimaginguk.bsky.social · 07/02/2025
Thanks to our partners! @physicsoflifeuk.bsky.social @blackinplantsci.bsky.social @royalmicrosoc.bsky.social
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Reposted by Dr. Nicola Smyllie
BioClocks UK @bioclocksuk.bsky.social · 10/02/2025
What are the pressing questions about mental health and the body clock? Have your say in picking the top 10 questions for research to answer: edinburgh.eu.qualtrics.com/jfe/form/SV_... @circadianmhnetw.bsky.social @jameslindalliance.bsky.social #circadian #chronobiology #mentalhealth #SciComm 🧪
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Dr. Nicola Smyllie @nsmyllie.bsky.social · 10/02/2025
My first post where I'm highlighting my latest sci-art collab! Artist, Laura Pearson-Clark, has created a stunning piece inspired by #astrocytes and #circadianrhythms in the brain. She draws parallels between brain networks and networks in the natural world. www.instagram.com/p/DF3Rna4IxV...
instagram.com
Redirecting...
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