Sign in

Institute of Molecular Genetics

@imgprague.bsky.social
1.1K followers 2.4K following 165 posts

Public scientific institution, part of the Czech Academy of Sciences. Research in molecular, structure and cell biology, immunology, genomics and bioinformatics.

PostsRepliesMedia
Institute of Molecular Genetics @imgprague.bsky.social · 31/08/2026
🧬 Same gene, different disease severity. Why? New research by @huranovalab.bsky.social reveals how different BBS2 mutations can have distinct effects on the BBS and ciliary function. 🔬 Published in Cell Communication and Signaling. Read more: www.img.cas.cz/2026/08/9200...
011
Institute of Molecular Genetics @imgprague.bsky.social · 27/08/2026
🧬 Who will be our next PhD Representatives? Sindija Šmite & Kristína Jamrichová have helped shape our PhD community for the past two years. Now we’re looking for two PhD candidates to work alongside our PhD Committee. 💬 Could it be you – or someone from your lab? 👀👇 @svobodalab.bsky.social
Two IMG PhD Representatives, Sindija Šmite and Kristína Jamrichová, standing together at the infamous staircase of the Institute of Molecular Genetics. The banner reads: “A healthy research culture starts with being heard. Meet the IMG PhD representatives.”
141
Institute of Molecular Genetics @imgprague.bsky.social · 28/07/2026
🇺🇸➡️🇨🇿 What does an undergraduate biology student from Boston take home after seven weeks at IMG? According to Sasha Vorobyov: Community. Curiosity. Excellence. Read her story: www.img.cas.cz/2026/07/9232...
img.cas.cz
Across the Atlantic for Science: An American Student’s Summer at the Czech Academy of Sciences
From Boston to Prague, Sasha Vorobyov spent seven weeks discovering how science is communicated beyond the laboratory—and found that learning goes both ways.
010
Institute of Molecular Genetics @imgprague.bsky.social · 27/07/2026
We are deeply saddened by the tragic passing of our colleague Professor Pavel Jungwirth. He inspired generations of scientists through his research, mentorship and unwavering commitment to science. Our sincere condolences to his family and colleagues at IOCB Prague. www.uochb.cz/en/news/811/...
uochb.cz
Pavel Jungwirth, a leading figure in the world of chemistry, has died
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences is deeply saddened to announce that on Thursday 23 July 2026, our outstanding colleague, teacher, mentor and…
061
Institute of Molecular Genetics @imgprague.bsky.social · 23/07/2026
🧬 Registration is now open for the 8th CCP Phenogenomics Conference! Join leading experts in rare diseases, disease models, gene & cell therapies, and translational research. 📍 Prague & Online 📅 9–11 September 2026 👇 More info below!
010
Institute of Molecular Genetics @imgprague.bsky.social · 15/07/2026
Looking for an employer where you don't have to choose between science and family? We're celebrating 15 years of our IMG preschool Atomik, supporting researchers through one of the most important stages of their lives. www.img.cas.cz/2026/07/9215...
020
Institute of Molecular Genetics @imgprague.bsky.social · 01/07/2026
👏 Congratulations to our colleague Prof. Meritxell Alberich Jordà! Meri served as Chair of the Scientific Program Committee for the EHA2026 Congress—one of the world's leading hematology meetings, bringing together more than 17,000 participants from around the globe.
010
Institute of Molecular Genetics @imgprague.bsky.social · 22/06/2026
🧬 News from IMG: David Staněk and colleagues report an antisense oligonucleotide strategy that rescues PRPF31 expression in patient-derived retinal cells carrying a splicing mutation causing retinitis pigmentosa. Published in Molecular Therapy. Read more HERE: 🔗 www.img.cas.cz/2026/06/9194...
033
Institute of Molecular Genetics @imgprague.bsky.social · 22/06/2026
🏆 Congratulations to Rohin Sengupta, PhD@IMG, on winning a Poster Prize at #EuroEvoDevo2026 in Glasgow! 🎉 His award-winning poster presented research from a project led by Iryna Kozmikova, exploring the evolutionary origins of the chordate body plan. A fantastic achievement among 314 posters
040
Reposted by Institute of Molecular Genetics
HuranovaLab @huranovalab.bsky.social · 28/02/2026
Today is the global Rare Disease Day 2026 and we together with colleagues from @imgprague.bsky.social want to raise awareness of research on rare diseases #ciliopathy #BardetBiedlSyndrome
021
Institute of Molecular Genetics @imgprague.bsky.social · 26/02/2026
🚀Open PhD positions! ⏳Time is running fast. 👋We are looking for you. 🧡APPLY NOW img.cas.cz/phd
000
Institute of Molecular Genetics @imgprague.bsky.social · 25/02/2026
🚀Open PhD position! 🩸Dissect the molecular mechanisms that enables balancing immune responsiveness with self-preservation in hematopoesis. We seek a PhD candidate for our supporting environment in a state-of-the-art institution. 🧡APPLY NOW img.cas.cz/phd
021
Institute of Molecular Genetics @imgprague.bsky.social · 24/02/2026
🚀Open PhD positions! 🧬We currently seek motivated PhD candidates for our projects at IMG. You may join Subhadip in a friendly, supportive and international Lab of Developmental Mechanobiology 🧡APPLY NOW img.cas.cz/phd
000
Institute of Molecular Genetics @imgprague.bsky.social · 24/02/2026
🚀Open PhD position! Lab of Integrative Biology is seeking a new talent. 💪Ultimate goal: Provide mechanistic insight into cytoskeletal targeting strategies in cancer and support the development of plectin-directed therapies. 🧡APPLY NOW img.cas.cz/phd
010
Institute of Molecular Genetics @imgprague.bsky.social · 23/02/2026
🚀Open PhD position! Join our newly established Lab of Immunophysiology. 👉How lymphoid and myeloid immune cells communicate to maintain homeostasis and respond to infection. Use mouse models, single-cell RNA seq, and genetic screens to uncover the regulatory pathways. 🧡APPLY NOW img.cas.cz/phd
011
Institute of Molecular Genetics @imgprague.bsky.social · 20/02/2026
🚀Open PhD position! Lactation requires tightly coordinated DNA replication, transcription, and DNA damage responses to sustain milk production. This PhD project will uncover the molecular mechanisms driving these processes in mammary epithelial cells. 🧡APPLY NOW img.cas.cz/phd
021
Institute of Molecular Genetics @imgprague.bsky.social · 14/02/2026
🚀Open PhD position! This project studies how primary cilium structure shapes its function and transport🦠, using advanced imaging to uncover mechanisms underlying ciliopathies🔬 Laboratory of Cell Motility is seeking a candidate with a deep interest in cilia biology 🧡APPLY NOW img.cas.cz/phd
021
Institute of Molecular Genetics @imgprague.bsky.social · 13/02/2026
We would like to invite you to celebrations of the Rare Disease Day organized by @czphenogenomics.bsky.social ⤵
000
Institute of Molecular Genetics @imgprague.bsky.social · 12/02/2026
Prague became my 2nd home, says Mehak about her PhD transition. Read the full interview ➡ www.img.cas.cz/2026/02/8964... Do you wish to join us in one of the safest cities in the world? 🧡APPLY NOW img.cas.cz/phd
010
Institute of Molecular Genetics @imgprague.bsky.social · 10/02/2026
🚀Open PhD position! Combine bioinformatics, single-cell and spatial multi-omics, with machine learning to uncover how the vertebrate head evolved. 🧫Laboratory of Transcriptional Regulation is seeking a highly motivated PhD candidate. Come and join us 🧡APPLY NOW img.cas.cz/phd
031
Institute of Molecular Genetics @imgprague.bsky.social · 09/02/2026
🚀Open PhD position! Genome instability promotes cancer development. This project will examine metabolic signaling defects to reveal cell vulnerabilities and novel chemotherapeutics. 🧬Laboratory of Cancer Cell Biology is seeking a new team player. Do you fit? 🧡APPLY NOW img.cas.cz/phd
022
Institute of Molecular Genetics @imgprague.bsky.social · 04/02/2026
🚀Open PhD position! Join Nenad at IMG and share with us: 💛Experience 🧡Friendship 💙Professionalism 💜PhD community APPLY NOW: img.cas.cz/phd
011
Institute of Molecular Genetics @imgprague.bsky.social · 03/02/2026
🚀Open PhD position! Ever wondered how cells polarize during early development? This PhD project dives into how mechanochemically-driven cell polarization evolves. 🧪 Genomics 🔬 Biophysics 📊 Fitness analysis Hooked? 🧡APPLY NOW img.cas.cz/phd
021
Institute of Molecular Genetics @imgprague.bsky.social · 29/01/2026
🚀Open PhD position! Join our newly established Lab of Immunophysiology. 🧪How do lymph nodes maintain immune tolerance? We‘ll study how fibroblastic reticular cells present self-antigens to support Treg maintenance and prevent autoimmunity. 👉Do you know lab work and coding? 🧡APPLY NOW img.cas.cz/phd
011
Institute of Molecular Genetics @imgprague.bsky.social · 27/01/2026
Joining IMG was the right choice 🎉 Read the full interview with our PhD student Kristína Jamrichová www.img.cas.cz/2025/02/8515... Be like Kristína, join us now! APPLY HERE img.cas.cz/phd
010
Institute of Molecular Genetics @imgprague.bsky.social · 26/01/2026
🚀Open PhD position! Lab of Cell and Developmental Biology is seeking a new team player. 🤝Join us to study stem cells, DNA repair, and how 💥cancer💥 really starts. 👉We seek independent thinker ready to learn both experimental and computational approaches. 🧡APPLY NOW img.cas.cz/phd
041
Institute of Molecular Genetics @imgprague.bsky.social · 22/01/2026
Join the Laboratory of Haematooncology and study chronic inflammation, aging and blood stem cells🩸 👩‍🔬👨‍🔬We seek a highly motivated, enthusiastic and hard-working PhD student with a strong team spirit 🤝We offer a friendly and supportive environment in a state-of-the-art institution APPLY: img.cas.cz/phd
020
Reposted by Institute of Molecular Genetics
Czech Academy of Sciences @czechacademy.bsky.social · 21/01/2026
Hope for rare anemia patients: Czech scientists create "perfect" mouse model Researchers from @czphenogenomics.bsky.social @imgprague.bsky.social achieved a breakthrough in understanding Diamond-Blackfan anemia, a severe genetic disease causing anemia and birth defects in children. bit.ly/4r4dg6I
onlinelibrary.wiley.com
Rps19R67∆ mutation creates a model of Diamond–Blackfan anemia and reveals downstream mediators of p53 pathway
Diamond–Blackfan anemia (DBA) is a rare bone marrow failure syndrome accompanied by cardiovascular, skeletal, and urogenital abnormalities. Most of the affected individuals carry mutations in ribosom...
021
Institute of Molecular Genetics @imgprague.bsky.social · 21/01/2026
💪PhD at IMG is always a good choice. Join @sindija.s, our student representative, and start enjoying what IMG offers. 🧡PhD Conference, Career Day, Green Swap and much more - come and see! Wanna help Sindi organizing PhD events? APPLY NOW ➡ img.cas.cz/phd
010
Institute of Molecular Genetics @imgprague.bsky.social · 19/01/2026
🚀Open PhD position! Lab of Integrative Biology @gregorlab.bsky.social is seeking a new talent. 💪Ultimate goal: Develop AAV-compatible mini-plectins to treat muscular dystrophy and cardiomyopathy 👉Profile: MSc, interest in biology, motivation, independence 🧡APPLY: img.cas.cz/phd
002
Institute of Molecular Genetics @imgprague.bsky.social · 15/01/2026
🤝Join us in Prague! Browse our open PhD positions at www.img.cas.cz/phd Join a global team and supportive environment, work with top-notch facilities, and enjoy our IMG community! ➡APPLY NOW!
032
Institute of Molecular Genetics @imgprague.bsky.social · 13/01/2026
🚀CALL for PhDs just launched🚀 We are accepting applications for the PhD program 🚨APPLY NOW!🚨 📅28. 2. 2026 ➡www.img.cas.cz/phd
041
Institute of Molecular Genetics @imgprague.bsky.social · 09/01/2026
🎉Publication in Nature Communications!🎉 The immune system at diagnosis in type 1 diabetes in children isn’t overactive, it’s immature🧒 Veronika Niederlova @vercanie.bsky.social and her colleagues showed that key immune cells fail to fully develop, allowing autoimmunity to arise⚖️
111
Reposted by Institute of Molecular Genetics
Veronika Niederlova @vercanie.bsky.social · 05/01/2026
Our paper on #tcells in Type 1 #Diabetes is now out in @natcomms.nature.com 👩‍🔬 rdcu.be/eXEH6 T cells in T1D show higher stem-like signatures and signs of Treg dysfunction. Thanks all the collaborators! @imgprague.bsky.social
rdcu.be
Imbalance of stem-like and effector T cell states in children with early type 1 diabetes across conventional and regulatory subsets
Nature Communications - Dysregulation of the T cell compartment is a driving factor in the development of Type 1 diabetes (T1D). Here, the authors present a single-cell gene expression analysis of...
031
Institute of Molecular Genetics @imgprague.bsky.social · 06/01/2026
🎉New publication in NatCom! @sumbalovakoledova.bsky.social and her colleagues identified specialized contractile fibroblasts that actively guide growth and branching of the mammary gland during puberty. 👉These cells are temporary – once their job is done, they transform into other cell types.
162
Institute of Molecular Genetics @imgprague.bsky.social · 31/12/2025
PF 2026 🧡💙
010
Institute of Molecular Genetics @imgprague.bsky.social · 24/12/2025
Merry and scientifically peaceful Christmas! ✨🧬We wish you lovely holidays, minimal cellular stress, stable DNA, functional RNA, well-tempered reactions, and lots of joy not only in the laboratory. 🧡💙Thank you for being with us. And we look forward to another year full of discoveries.
000
Institute of Molecular Genetics @imgprague.bsky.social · 16/12/2025
📣We’re proud to announce the successful completion of our first Single-Cell RNA-seq course at the Institute of Molecular Genetics 📅 1–3 December 2025 🤝 In collaboration with ELIXIR CZ, @ibtcas.bsky.social and MetaCentrum
121
Institute of Molecular Genetics @imgprague.bsky.social · 15/12/2025
🔥 WE ARE HIRING! 🔬Join Filip Šenigl and dive into the world of somatic hypermutation, DNA repair, and transcriptional kinetics! Work with cutting-edge methods (CRISPR/Cas9-degron, CUT&RUN, integration libraries) and contribute to high-impact immunology research. www.img.cas.cz/group/jiri-h...
121
Institute of Molecular Genetics @imgprague.bsky.social · 12/12/2025
🚨 New publication in Leukemia! The germline JAK2-R1063H variant drives risk of thrombosis and accelerates leukemic transformation. Our data highlight its impact on stem cell aging and disease progression. ​ 👏Great work by Veronika Zimolová, Lucie Láníková et al
141
Reposted by Institute of Molecular Genetics
HuranovaLab @huranovalab.bsky.social · 08/12/2025
Our lab has two new members Hanka and Eashayan #cilia #fun #Xmas #photoshooting @imgprague.bsky.social
051
Institute of Molecular Genetics @imgprague.bsky.social · 25/11/2025
🚨Welcoming António P. Baptista, who just launched the Laboratory of Immunophysiology at IMG. His research dives into how immune cells develop and react during infection. ➡Read what he said about his experience, Prague and moving with family: www.img.cas.cz/2025/11/8874...
011
Institute of Molecular Genetics @imgprague.bsky.social · 07/11/2025
🎓 PhD Bootcamp: A weekend full of learning, exploring, and networking!🌟 This traditional event brought together our new PhD students - and for the first time, also the advanced ones🤝 We didn’t forget to spend time outside 🏞️ and enjoy fun evenings together!✨
020
Institute of Molecular Genetics @imgprague.bsky.social · 05/11/2025
New publication in Nature Communications from Lukáš Čermák lab ⚖️Cells need the right balance between old and new MCM proteins for error-free DNA copying 🧩We identified DCAF12 as a key factor that controls how new MCM complexes are assembled www.nature.com/articles/s41...
nature.com
CRL4DCAF12 regulation of MCMBP ensures optimal licensing of DNA replication - Nature Communications
MCM2-7 complexes drive genome duplication, but their assembly in human cells is not fully understood. Here, the authors identify the CRL4-DCAF12 ubiquitin ligase as crucial for MCM2-7 maturation, safe...
131
Institute of Molecular Genetics @imgprague.bsky.social · 17/10/2025
🧬Get a feeling of electron microscopy in biomedicine in one week 🔬Learn principles of electron microscopy and become an independent user 👩‍🏫Highly experienced tutors – focus on hands-on training Register now – spots are limited to 15 participants! course.img.cas.cz/tem/
132
Institute of Molecular Genetics @imgprague.bsky.social · 16/10/2025
Huge congratulations to Jiří Černý! 📸Nikon Small World - 2025 Photomicrography Competition announced its winners! www.nikonsmallworld.com
130
Reposted by Institute of Molecular Genetics
Czech Academy of Sciences @czechacademy.bsky.social · 15/10/2025
NIVB unites top research institutes in the Czech Republic accelerating drug and vaccine development against viral and bacterial diseases: @iocbprague.bsky.social @imgprague.bsky.social @mbuavcr.bsky.social @charlesuni.cuni.cz @masarykuniversity.bsky.social @vschtpraha.bsky.social Biology Centre CAS
174
Reposted by Institute of Molecular Genetics
IOCB Prague @iocbprague.bsky.social · 13/10/2025
👥 Last month, we hosted Dr. Hana Hanzlikova ( #unibern / @imgprague.bsky.social @czechacademy.bsky.social) for another lecture in the #DanaHockováLecture Series. #IOCB #IOCBPrague #WomenInScience
061
Institute of Molecular Genetics @imgprague.bsky.social · 10/10/2025
“Scientists’ salaries in the Czech Republic are significantly lower than in Western Europe, which makes it difficult to attract top international talent,” says Meritxell Alberich Jordà, one of the Forbes Top Women Scientists in the Czech Republic forbes.cz/nejvetsi-brz...
forbes.cz
Největší brzda vědy? Kurýr si v Česku vydělá víc než univerzitní profesor
Kvůli nízkým platům ve vědě přichází Česko o řadu talentovaných lidí, kteří odcházejí dělat špičkovou vědu do světa.
021
Reposted by Institute of Molecular Genetics
Zuzana Sumbalova Koledova @sumbalovakoledova.bsky.social · 06/10/2025
Our study on fibroblast functional heterogeneity in mammary glands is out in @natcomms.nature.com! This tour de force by Jakub Sumbal reveals contractile fibroblasts in TEB niche. Great collaboration @imgprague.bsky.social with @frelab.bsky.social @institutcurie.bsky.social ▶️https://rdcu.be/eIIKD
031