A decade on from the launch of an ambitious project, it’s time to revisit the reasons for constructing a human genome from scratch.

A decade on from the launch of an ambitious project, it’s time to revisit the reasons for constructing a human genome from scratch.

Job Description The Department of Genome Sciences has an outstanding opportunity for a Research Scientist Engineer 2 to join the team. About this Opportunity Reporting to the Principal Investigator, t...

The ability to design and engineer mammalian genomes across arbitrary length scales would transform biology and medicine. Such capabilities would enab…

We are working to solve the biggest mysteries in bioscience.

The nuclear lamins are extremely long-lived proteins in most cell types. As a consequence, lamin function cannot be effectively dissected with temporal precision using standard knock-down approaches. ...

Mammalian metabolic engineering is critical to advancing basic biology, bioproduction, and cell therapy. However, as pathway complexity increases, so does the size of both the combinatorial design spa...

Mammalian metabolic engineering is critical to advancing basic biology, bioproduction, and cell therapy. However, as pathway complexity increases, so does the size of both the combinatorial design spa...

Mammalian cells were engineered to synthesize valine, a metabolic capacity that had been lost from the lineage of higher eukaryotes for >500 million years.

Mammalian metabolic engineering is critical to advancing basic biology, bioproduction, and cell therapy. However, as pathway complexity increases, so does the size of both the combinatorial design spa...

The REX element is associated with long-range enhancer–promoter interactions.

A barcoded CRISPR base editing system isolates target clones from complex mammalian, yeast and bacterial populations.

Background Inducible gene expression circuits enable precise control over target gene activation and are widely used in direct reprogramming. However, their usability is often compromised by DNA methy...

We are working to solve the biggest mysteries in bioscience.

June 19-20 2025, Vancouver, BC, Canada