One-shot tissue dynamics reconstruction can infer changes in tissue composition over time, from single-time-point spatial proteomics of human cancers.

Integration of pre-treatment tumour features in predictive models using machine learning could inform on response to therapy.

Scientists uncover how a small number of cancer cells can drive tumour growth in breast cancer.

Inflammatory cytokines hijack a brain circuit to cause apathy in cancer

Epigenetic alterations co-evolve with genetic mutations to drive carcinogenesis and treatment response. Resolving genome-epigenome coevolution requires accurate multi-omic single cell measurement. Her...

View details and apply for this Postdoctoral Training Fellow - Computational Single Cell Biology (Dr Stephen-John Sammut) vacancy in Chelsea . Salary: Starting salary is based on previ...

Nature Communications - NA-PHER2 was a neoadjuvant trial of HER2-targeted trastuzumab and pertuzumab plus the CDK4/6 inhibitor palbociclib with or without endocrine therapy in HER2-positive,...

npj Breast Cancer - A pooled analysis evaluating prognostic significance of Residual Cancer Burden in invasive lobular breast cancer

Our proposed method shows promise as a tool for studying the tumour vasculature and its relationship with surrounding cells and tissue types. Furthermore, the correlation with tumour grade highlights ...

New data tool could bring RNA sequencing into standard clinical practice, improving diagnosis and treatment

Integration of pre-treatment tumour features in predictive models using machine learning could inform on response to therapy.