Sign in

Long V. Nguyen

@nguyenlab.bsky.social
44 followers 64 following 12 posts

Oncologist-Scientist @ Princess Margaret Cancer Centre & University of Toronto 🇨🇦 Transcriptional plasticity, functional clonal heterogeneity, cancer stem cells 🧬🔬🧫 lvnguyenlab.ca

PostsRepliesMedia
Long V. Nguyen @nguyenlab.bsky.social · 16/09/2026
Honoured to be named one of Canada’s #Top40Under40! Grateful to my mentors, trainees, collaborators, friends and family for their support. Excited to continue advancing #CancerResearch and patient care @uhn.ca @uhnresearch.ca
131
Long V. Nguyen @nguyenlab.bsky.social · 07/04/2026
🚨 Pre-print alert! Kronheim S et al. Chemotherapy reshapes cellular clonal landscape via persister programs in breast cancer xenografts: doi.org/10.64898/202... In collaboration with @carloscaldas1960.bsky.social & @fgaiti.bsky.social #CancerResearch #SingleCell #Chemotherapy #TumorEvolution
doi.org
230
Reposted by Long V. Nguyen
Carlos Caldas 🇵🇹🇮🇱🇪🇺🇬🇧 @carloscaldas1960.bsky.social · 01/12/2025
Important protocol from @nguyenlab.bsky.social that details method used in our paper published recently @cp-cellreports.bsky.social: www.cell.com/cell-reports... www.sciencedirect.com/science/arti...
sciencedirect.com
Protocol to track single-cell-derived clones using DNA barcoding combined with single-cell RNA sequencing
Clonal fitness and plasticity drive tumor heterogeneity contributing to disease progression and treatment resistance. Here, we provide a protocol to t…
121
Reposted by Long V. Nguyen
Cell Reports Medicine @cp-cellrepmed.bsky.social · 11/11/2025
Online now: The tumor microenvironment of 14,837 breast cancers is associated with clinical outcome independently of genomic subtypes
dlvr.it
The tumor microenvironment of 14,837 breast cancers is associated with clinical outcome independently of genomic subtypes
Tu et al. present a systematic analysis of the tumor microenvironment across 14,837 breast cancers, identifying distinct cellular patterns that predict disease-specific survival independently of genomic and intrinsic subtypes. Characterizing microenvironment composition may provide critical prognostic markers that can complement current molecular classification for treatment selection and preventing recurrence.
0108
Reposted by Long V. Nguyen
Kevin Tu @kevinjtu.bsky.social · 10/11/2025
My poor laptop wishes I learned how to use the cluster earlier, but it’s sacrifice was not in vain! We learned some important things about the breast cancer tumor microenvironment, described in our paper published today: www.cell.com/cell-reports... Here's the 🧵
1145
Reposted by Long V. Nguyen
Research at UHN @uhnresearch.ca · 10/07/2025
Most #cancer cells aren’t able to propagate tumours—but a rare few can. Using genetic barcodes, a team @pmresearch-uhn.bsky.social tracked these rare clones—revealing how they evolve, adapt, and resist treatment. A step toward more targeted cancer therapies. 🔗: www.uhnresearch.ca/news/rare-ca...
174
Long V. Nguyen @nguyenlab.bsky.social · 12/05/2025
I am excited to share the latest publication from the Nguyen, Caldas @carloscaldas1960.bsky.social and Rueda labs @ruedalab.bsky.social. This was a massive effort from a fantastic team and I’m grateful to everyone on the paper for their work on this project! doi.org/10.1016/j.ce... #bcsm #PDTX
doi.org
Redirecting
3146
Long V. Nguyen @nguyenlab.bsky.social · 25/04/2025
wp.me/pfyNu9-lb
wp.me
Welcome to the Nguyen lab, Dr. Sahil Sharma!
We welcomed Dr. Sahil Sharma as the newest addition to the Nguyen lab with our first lab retreat!  Dr. Sharma comes to us after completing a PhD in Experimental Medicine at McGill University w…
030