iiinova — where your digital self keeps evolving

How cool is that? I am utterly exhausted & mind-boggled with the phenomenal synthetic hybrid chromosomes (Chromosome I of S. cerevisiae & S. paradoxus) & unexpected colony morphologies described by #ChrisNeVille lab of #IanEhrenreich @usc.edu @dornsife.usc.edu #Yeast26 @genetics-gsa.bsky.social

[1/3] Monday at #Yeast26 was extremely busy (no excuses), but I just wanted to thank @maitreya.bsky.social @uwgenome.bsky.social , #MichaelLaw @stockton.edu (and…help!! I’m missing names!!) for putting together the “Teaching with Purpose: Implementing the New #Genetics #LearningOutcomes” workshop,…

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Nick Silva @nicholasjsilva.bsky.social · 29/04/2026

How can you not stop in your tracks when you see “Yeast Killer” on a slide?? Extremely cool to learn about #mycoviruses from #MengxiTan lab of @marcmeneghini.bsky.social @utoronto.ca. Incredible to see they’ve uncovered even more #viruses with the #1011YeastGenomes #Yeast26 @genetics-gsa.bsky.social

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Reposted by Sally G Pasion

My paper is finally out in @natcomms.nature.com ! 🐟🐭🧠 Thankful to the contributors and @annamolofskylab.bsky.social for the support! How does the developing brain clear millions of dying neurons? Read below, if interested. #zebrafish #neuroscience #microglia #devbio @zebrafishrock.bsky.social 1/5

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Surprised that #evolution of #fluconazole #DrugResistance monitored in yeast lineages in different environments collapsed into six fitness response clusters. Stunning work by @kgslab.bsky.social #ArizonaStateUniversity #ASUBiodesignCenterforMechanismsofEvolution #Yeast26 @genetics-gsa.bsky.social

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Welcome to Wednesday morning and the FINAL #Yeast26 session focusing on #Evolution and #PopulationGenetics with co-cruise directors @maitreya.bsky.social @uwgenome.bsky.social and #GregoryLang #LehighUniversity to close our YGM! @genetics-gsa.bsky.social

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Congratulations to @schacherer.bsky.social @unistra.fr recipient of the #Yeast26 GSA Medal! Great to hear the journey to identifying structural variants in #1011YeastGenomes, tackling heritability, genetic diversity, and genotype-phenotype @genetics-gsa.bsky.social

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Thanks #LindaHuang @umassboston.bsky.social for reminding/teaching us to end yeast #meiosis with four spores requires wrapping each nucleus with a prospore membrane, like pulling a ski mask down from the top of your head past your ears and under your chin. #Yeast26 @genetics-gsa.bsky.social

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How to monitor the #stress response of one protein in a single cell in response to salt stress as shared by #RachelKocik lab of @audreygasch.bsky.social #UWisc-Madison #Yeast26 @genetics-gsa.bsky.social

Delineating the role of #Bck2 in controlling cell size for triggering Start presented by #ShifuWu lab of #JanSkotheim @stanford.edu #Yeast26 @genetics-gsa.bsky.social

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As a yeast geneticist, I wonder how yeast cells die. This clever Yeast Lifespan Machine holds the mother cell and buds are washed away to allow study of the aging mother cell. #KiyanShabestary #CalicoLifeSciences has focused on analyzing gene expression changes in scRNAseq from aging yeast. #Yeast26

Fascinating to see the detailed analysis of the #fibril structures generated by the #prion form of the translation termination factor #Sup35 in yeast shared by #WenjuanZhang @ucl.ac.uk #amyloid #[PSI^+] #Yeast26 @genetics-gsa.bsky.social

I am easily fascinated by #WordClouds and these are all about #aging! And then you get to see an atlas of the age-sensitive proteome (where are they, how much, protein interactions) #KaiZhou @buckinstitute.org #Yeast26 @genetics-gsa.bsky.social #HallmarksOfAging

Wow! In this morning’s #Yeast26 Disease Models and Aging session, @richasardana.bsky.social @cornelluniversity.bsky.social @cornellvet.bsky.social is using #Ers1, the yeast homolog of #cystinosin (#CTNS) to uncover potential drug targets for #Cystinosis @genetics-gsa.bsky.social

As we start this morning’s #Yeast26 session on “Disease Models & Aging” with co-chairs #DanielGottschling, #CalicoLifeSciences and #AllysonO'Donnell #UniversityOfPittsburgh, I'm having a back-to-the-future moment of a long-ago meeting enthralled when Dan Gottschling explained aging studies in yeast😮

Learned about using an oligo pull down assay to show that the zinc finger domain of transcription factor #Mig1 binds to #GQuadruplex DNA from #MeenuSharma from lab of #NayunKim #UTAustinCollegeOfPharmacy #Yeast26 @genetics-gsa.bsky.social #G4

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Thanks #BrianMetzger #PurdueUniversity for your deep dive into how gene expression noise contributes to the evolution of gene regulation! #Yeast26 @genetics-gsa.bsky.social

I just learned I have ONE thing in common with #Yeast26 YGM Lifetime Achievement Awardee, #PhilHieter @ubcmedicine.bsky.social: We never took a formal genetics class😀. Congratulations to an inspiring scientist who has impacted and improved the yeast community and beyond. @genetics-gsa.bsky.social

I’ve been chasing #helicases intentionally or accidentally for decades. Such a cool surprise to hear from #MatthewBochman #IndianaUniversity about using Helicase-AID to connect the yeast #RECQL4 homolog #Hrq1 to #RNAPolIII transcription. #Yeast26 @genetics-gsa.bsky.social

Love hearing about #OkazakiFragmentProcessing!! Thought-provoking results about changes in OFP when dNTP levels are elevated or skewed using rnr1 mutants from #JenniferSurtees @ubuffalo.bsky.social. Eager to hear more – no pressure! #Yeast26 @genetics-gsa.bsky.social

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Having fun learning about #LatticePoisoning & #Ty1 retrotransposon restriction factors from #SeanBeckwith @hopecollege.bsky.social. Looking forward to seeing undergrads (#AwesomeAbraham, #AlexaMacKersie, & #MackenzieStreeter) who are presenting Ty1 posters at #Yeast26 too! @genetics-gsa.bsky.social

Intriguing integrated model #CellMap approach to support predicting gene functions and protein-protein interactions in yeast and in humans presented by #DuncanForster @utoronto.ca @donnellycentre.bsky.social labs of @garybader.bsky.social and #CharlesBoone #Yeast26 @genetics-gsa.bsky.social

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Happy Monday #Yeast26 people!! It’s Genomics and Systems Biology to start this morning with co-chairs @elena-kuzmin.bsky.social @concordia.ca and #SabineVanSchie @umasschan.bsky.social @genetics-gsa.bsky.social

Congratulations to #KarenArndt #UniversityOfPittsburgh presenting the #Yeast26 Lee Hartwell lecture and sharing the journey from #RTF1 to the #PafComplex (#Paf1C) (leaving me scrambling to learn about #AnchorAway). @genetics-gsa.bsky.social

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It’s the first #Yeast26 #GeneRegulation session, and I’m learning about #plant TPL corepressor interacting with SPT4, SPT5, and SPT6 from @leydonsaurus.bsky.social #UniversityOfWashington with help from a #SyntheticGeneticArray (I see you #GrantBrown @utoronto.ca) @genetics-gsa.bsky.social

Man wearing white short sleeve shirt with some blue horizontal stripes is standing at a podium to the right of a giant slide about that is titled: We identified genetic interactors through Reporter Synthetic Genetic Array. On the slide, below the title is a black horizontal line. On the left half of the line, there is a red rectangle labeled RFP. On the right half of the line is a yellow rectangle labeled YFP. There is the word “Repressed” positioned above and between the two rectangles, and there is an inhibitory line that points from “Repressed” to the horizontal line between the two colored rectangles. To the right of the horizontal line and the yellow YFP rectangle is a representation of a budding yeast cell (a large circle with a small circle positioned at about 4 o’clock of the large circle, outside of the large circle, but touching the edge of the large circle) that is filled in with the color red. Below the horizontal line is an arrow pointing to a grey rectangle that is a photograph with an ordered array of spots that appear to be different colors. A small 4 x 4 patch of the spots has been zoomed in and sits above the top right of grey rectangle and shows some spots are yellow and some are red. On the bottom right half of the slide is visible the image of a man’s face (a collaborator).

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Good morning #Yeast26, and thanks for coming to today’s first session on #GenomeIntegrity!! What a breathtaking space for pondering deep scientific thoughts😊. @genetics-gsa.bsky.social

Large meeting hall with open beams and arches on the ceiling over an array of rows of wood chairs harboring over 100 folks facing the camera.

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