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Jose A. Seoane

@seoaneja.bsky.social
290 followers 490 following 6 posts

Head of Cancer computational biology group @ VHIO Stanford & UoBristol postdoc, UDC PhD. Repunantiño

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Reposted by Jose A. Seoane
Vall d’Hebron Institute of Oncology @vhio.bsky.social · 29/09/2026
A study led by Alena Gros, first-authored by Andrea García-Garijo, shows how a blood sample could help identify cancer-specific targets for personalized immunotherapy. ➡️ linke.to/CancerDiscoveryAlenaGros #CAIMI @isciiisalud.bsky.social @contracancerinv.bsky.social @aacrjournals.bsky.social
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Reposted by Jose A. Seoane
Nature @nature.com · 13/06/2026
Why are so many young people developing cancers once considered the purview of old age? go.nature.com/49Yh03A
go.nature.com
Why are so many young people getting cancer? What researchers do and don't know
Nature - Candidates for the trend are emerging, but are likely to vary from one type of tumor to another.
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Reposted by Jose A. Seoane
Vall d’Hebron Institute of Oncology @vhio.bsky.social · 06/06/2026
The last call of our VIDA Postdoctoral COFUND Programme is officially OPEN‼️ 🚀  Funded by a Marie Skłodowska-Curie Actions COFUND Grant, #VHIOVIDAEU is recruiting 4️⃣ postdocs. 🗓️ Apply by Aug 20 👉 linke.to/VHIOVIDAprogramme25 #VHIOVIDA #TranslationalResearch #VHIOAcademy @ec.europa.eu
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Reposted by Jose A. Seoane
Fundación Científica de la Asociación Española Contra el Cáncer @contracancerinv.bsky.social · 31/05/2026
Día Mundial Sin Tabaco. La investigación en prevención ha demostrado que evitar el consumo de tabaco es una de las medidas más eficaces para reducir el riesgo de desarrollar cáncer 💚 Porque investigar también es prevenir #DíaMundialSinTabaco #TodosContraelCáncer #Investigación
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Reposted by Jose A. Seoane
Nature @nature.com · 07/05/2026
Nature research paper: Non-invasive profiling of the tumour microenvironment with spatial ecotypes go.nature.com/42USyMo
go.nature.com
Non-invasive profiling of the tumour microenvironment with spatial ecotypes - Nature
Multimodal machine learning reveals that tumour microenvironments can be decomposed into spatially organized multicellular ecosystems, termed spatial ecotypes, that can be accessed non-invasively via liquid biopsy and used to profile individual cancers and target treatments.
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Reposted by Jose A. Seoane
The New York Times @nytimes.com · 30/04/2026
J. Craig Venter, a scientist and entrepreneur who decoded the human genome, has died at 79.
nyti.ms
J. Craig Venter, Scientist Who Decoded the Human Genome, Dies at 79
A risk-taking outsider, he brought speed, competition and controversy to one of science’s biggest races.
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Reposted by Jose A. Seoane
Nature Medicine @natmed.nature.com · 24/04/2026
An analysis of #exposome traits in patients with early onset CRC (<50 yrs) compared with late-onset CRC (≥70 yrs) based on epigenetic markers shows that pesticide usage, in particular picloram, is associated with early onset colon and rectal cancer.
dlvr.it
Epigenetic fingerprints link early-onset colon and rectal cancer to pesticide exposure - Nature Medicine
An analysis of exposome traits in patients with early-onset colorectal cancer (CRC) (&lt;50 years) compared with late-onset CRC (≥70 years) based on epigenetic markers shows that pesticide usage, in particular of picloram, is associated with early-onset CRC.
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Reposted by Jose A. Seoane
Eric Topol @erictopol.bsky.social · 21/04/2026
Why are we seeing so much early-onset colorectal cancer? The correlation with pesticide exposure and its epigenetic signature, adjusted for all known risk factors. (doesn't establish cause and effect) nature.com/articles/s41...
nature.com
Epigenetic fingerprints link early-onset colon and rectal cancer to pesticide exposure - Nature Medicine
An analysis of exposome traits in patients with early-onset colorectal cancer (CRC) (&lt;50 years) compared with late-onset CRC (≥70 years) based on epigenetic markers shows that pesticide usage, in p...
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Fundación Científica de la Asociación Española Contra el Cáncer @contracancerinv.bsky.social · 21/04/2026
🔬 Un estudio del @vhio.bsky.social publicado en Nature Medicine analiza por primera vez cómo el exposoma (entorno y estilo de vida) puede influir en el cáncer colorrectal en menores de 50 años a través de cambios en el ADN.
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Cancer Computational Biology @cancercompbiolab.bsky.social · 21/04/2026
NEW 📄! Our last Nature Medicine paper, led by @silvanamaas.bsky.social and @seoaneja.bsky.social , identifies picloram (herbicide) as a novel risk factor on early-onset colorectal cancer ( #eoCRC), while confirming well-known risk factors. www.nature.com/articles/s41.... #exposome #epigenetics +
nature.com
Epigenetic fingerprints link early-onset colon and rectal cancer to pesticide exposure - Nature Medicine
An analysis of exposome traits in patients with early-onset colorectal cancer (CRC) (&lt;50 years) compared with late-onset CRC (≥70 years) based on epigenetic markers shows that pesticide usage, in p...
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Science Media Centre España @sciencemediacentre.es · 21/04/2026
➡️Un equipo de @vhio.bsky.social relaciona los cambios provocados por dieta, tabaco y exposición a pesticidas con el desarrollo de cáncer colorrectal en menores de 50 años 🗨️ Robin Mesnage: "Se necesita más trabajo, en concreto, con datos de exposición directa" sciencemediacentre.es/relacionan-l...
sciencemediacentre.es
Relacionan los cambios provocados por dieta, tabaco y exposición a pesticidas con el desarrollo de cáncer colorrectal en menores de 50 años
Un equipo del Vall d'Hebron Instituto de Oncología, en Barcelona, publica un estudio que aborda el impacto del exposoma –cambios en el estilo de vida y factores ambientales– en el cáncer colorrectal d...
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Reposted by Jose A. Seoane
Vall d’Hebron Institute of Oncology @vhio.bsky.social · 21/04/2026
A @natmed.nature.com : un estudi liderat pel VHIO, amb José Antonio Seoane i Silvana Maas, vincula canvis epigenètics per la dieta, el tabac i l’exposició a pesticides amb el càncer colorectal en menors de 50 anys. ➡️ linke.to/NatureMedSeoane #AECCVHIO @caixaresearch.bsky.social
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Jose A. Seoane @seoaneja.bsky.social · 21/04/2026
Delighted to share our new paper which has just been published in Nature Medicine. www.nature.com/articles/s41...
nature.com
Epigenetic fingerprints link early-onset colon and rectal cancer to pesticide exposure - Nature Medicine
An analysis of exposome traits in patients with early-onset colorectal cancer (CRC) (&lt;50 years) compared with late-onset CRC (≥70 years) based on epigenetic markers shows that pesticide usage, in p...
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Reposted by Jose A. Seoane
Nature Portfolio @natureportfolio.nature.com · 15/04/2026
An analysis in Nature Health reveals spatial patterns of pesticide exposure and liver tissue-derived molecular signatures across Peru, establishing links between pesticide usage and cancer insurgence at the national scale. go.nature.com/41hOBAK 🧪
This is figure 1, which shows a high-resolution environmental model of pesticide risk across Peru, designed to support spatial cancer epidemiology.
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Reposted by Jose A. Seoane
Cell - a Cell Press journal @cp-cell.bsky.social · 07/04/2026
Now online! Accelerating discovery of cancer causes for prevention in the era of rising early-onset cancers
dlvr.it
Accelerating discovery of cancer causes for prevention in the era of rising early-onset cancers
Rising early-onset cancers challenge existing frameworks for understanding and managing cancer. This perspective outlines a roadmap for addressing this challenge by advancing the discovery of cancer causes, cancer risk assessment, and cancer preventability characterization.
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Reposted by Jose A. Seoane
danapeer.bsky.social @danapeer.bsky.social · 27/03/2026
I am very pleased with our latest paper showing that cells can remember past injury for a long time! Here a simple interpretable AI was used as a discovery tool to pinpoint the DNA code and biological mechanism. Big foundation models failed. www.science.org/doi/10.1126/...
science.org
Distinctive DNA sequence features define epigenetic longevity of inflammatory memory
Tissues harbor memories of inflammation, which heighten sensitivity to diverse future assaults. Whether and how these adaptations are sustained through time and cell division remain poorly understood....
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Reposted by Jose A. Seoane
Jason Buenrostro @jbuenrostro.bsky.social · 26/03/2026
It’s well known that inflammation increases cancer risk, but how? The answer: the epigenome "remembers" inflammation and primes stem cells for cancer. Here is our paper: nature.com/articles/s41... And a special shoutout to the lead author @snaga13.bsky.social A 🧵
nature.com
Epigenetic memory of colitis promotes tumour growth - Nature
Colonic stem cells retain a memory of inflammation following disease resolution and there is a mechanistic link between chronic inflammation and malignancy, suggesting potential strategies to mitigate...
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Reposted by Jose A. Seoane
CNAG @cnag-eu.bsky.social · 17/03/2026
🧬Continuem celebrant els 25 Anys del Projecte Genoma Humà! 🗣️Descobreix com va ser la creació del primer llibre de la vida, de la mà d'un dels seus creadors: el Dr. @ewanbirney.bsky.social 🗓️08 d'abril, 19h. CosmoCaixa 📝Inscripcions: cosmocaixa.org/es/p/ewan-bi... @easigen-eu.bsky.social #ICTSNews
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Reposted by Jose A. Seoane
Nature @nature.com · 13/03/2026
The rates of more than a dozen cancers are increasing among adults under the age of 50. What are the reasons behind it? go.nature.com/4cKxhLN
go.nature.com
Why are so many young people getting cancer? What the data say
Clues to a modern mystery could be lurking in information collected generations ago.
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Anthony Mathelier @amathelier.bsky.social · 03/03/2026
👇 Still a couple of days to apply to join our amazing team as a Research Scientist / Software Developer. Apply if you want to build and maintain reproducible pipelines for large-scale genomic analysis to support our study of breast cancer cis-regulatory signatures and JASPAR, among other things.
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Cancer Computational Biology @cancercompbiolab.bsky.social · 26/01/2026
What makes HR+ breast cancer tumors immune-cold? New work shows how ER signaling hijacks LCOR, suppressing tumor immunogenicity. Our PI @seoaneja.bsky.social participates on this study led by @tceliaterrassa.bsky.social, uncovering a target to sensitize tumors to ICB. www.jci.org/articles/vie...
jci.org
JCI - Estrogen receptor signaling drives immune evasion and immunotherapy resistance in HR+ breast cancer
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Trevor Graham @trevorgraham.bsky.social · 07/01/2026
With the start of our new study trying to find causes of bowel cancer in young people hitting the headlines today: www.bbc.co.uk/news/article... I'm so glad to see bold efforts to raise awareness, like this giant 5x3m poster on the Croydon station platform I pass by on my to the lab each day
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Kevin Monahan @kevinmonahan.bsky.social · 07/01/2026
Read about our plans to analyse the century long archive at St Mark's Hospital to understand why more young people are being diagnosed with bowel cancer @trevorgraham.bsky.social www-bbc-co-uk.cdn.ampproject.org/c/s/www.bbc....
www-bbc-co-uk.cdn.ampproject.org
Century-old tumours could reveal why more young people are getting bowel cancer - BBC News
Bowel cancer in people under the age of 50 is increasing worldwide and scientists are striving to find out why.
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Vall d’Hebron Institute of Oncology @vhio.bsky.social · 22/11/2025
🚀 Ready to take your career to the next level❓ 8–10 fully funded PhD fellowships now open for Life Sciences & Medical students! Apply now and be the next to turn cancer discoveries into cures  👉 linke.to/PhDfellowships25_VHIO 📅 Deadline: 28 November #SOMMVHIO @cerca.cat
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Cancer Computational Biology @cancercompbiolab.bsky.social · 16/10/2025
Last week, pre-doctoral researchers @juanravm.bsky.social and @mariabuxi.bsky.social attended #CCEsumschool25 to showcase some of our group's research 👏🏼 Thanks to @vhio.bsky.social and @cancercoreeurope.bsky.social for this valuable opportunity for the next generation of cancer researchers 🔬
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Reposted by Jose A. Seoane
Trevor Graham @trevorgraham.bsky.social · 10/09/2025
Studying cancer evolution needs multi-region or single cell seq for phylogenetics, right? Amazingly (I think!) we found single-sample bulk methylation suffices, via analysis of "fluctuating methylation". In @nature.com today led by brilliant @calumgabbutt.bsky.social www.nature.com/articles/s41...
nature.com
Fluctuating DNA methylation tracks cancer evolution at clinical scale - Nature
Cancer evolutionary dynamics are quantitatively inferred using a method, EVOFLUx, applied to fluctuating DNA methylation.
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elDiario.es @eldiario.es · 10/09/2025
Un algoritmo epigenético rastrea el origen del cáncer y predice su progresión
eldiario.es
Un algoritmo epigenético rastrea el origen del cáncer y predice su progresión
Un equipo científico hispano-británico halla una 'caja negra' del cáncer que puede ayudar a desvelar la procedencia de los tumores y anticipar su evolución
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Anshul Kundaje @anshulkundaje.bsky.social · 19/08/2025
@jengreitz.bsky.social l & my lab want to co-hire a computational biologist/biostatistician with project management expertise to help map the regulatory code of the human genome and discover genetic mechanisms of disease. Details below careersearch.stanford.edu/jobs/computa... Plz RT
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Oscar M Rueda @ruedalab.bsky.social · 13/08/2025
Are you looking for a statistics/ML postdoc? Come to work with @antonis02.bsky.social and me in the NEMO study, an international collaboration aiming to detect ovarian cancer earlier through cutting-edge multi-omics, funded by the Alliance for Cancer Early Detection. www.cam.ac.uk/jobs/researc...
cam.ac.uk
Research Associate*/Research Assistant in Multi-omics Early Detection of Ovarian Cancer (Fixed Term)
An exciting opportunity has arisen for a highly motivated Research Associate to join the Centre for Cancer Genetic Epidemiology (CCGE) at the Department of Public Health & Primary Care, University of
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Santiago Carmona 🧬 🖥️ 🧑🏾‍🔬 @carmonation.bsky.social · 05/08/2025
📢 We have an open position at University of Geneva for a PhD student with CS/Math/Physics background to study adaptive immune responses using deep learning. If interested please contact me directly!
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Barriga Lab VHIO @barrigalabvhio.bsky.social · 21/07/2025
We are hiring! We are searching for a motivated bioinformatics scientist interested in joining our team! Apply below: jobs.vhio.net/jobs/6203915...
jobs.vhio.net
2025-040-01 Bioinformatics Scientist - VHIO
Under the leadership of Josep Tabernero, VHIO is an internationally recognized cancer center. Its multidisciplinary, collaborative model drives scientific progress and innovative cancer treatments.
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Reposted by Jose A. Seoane
euanashley @euanashley.bsky.social · 14/06/2025
Atul Butte died yesterday. The world lost a giant. A big bear of a man. With a huge smile. With love for everyone. With energy that could power a room. I loved everything about Atul. I loved how he was always happy. I loved how excited he was about science and helping people.
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David Picard @davidpicard.eurosky.social · 06/06/2025
Reminder that the MSCA postdoctoral program exists. If you have a PhD and want to work in a European lab, you have until September to apply. Just contact them now. ec.europa.eu/info/funding...
ec.europa.eu
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Jonathan Pritchard @jkpritch.bsky.social · 01/06/2025
I have an opportunity to hire a staff scientist for my lab. Looking for someone with outstanding skillset in ML/statistics, genomics applications; interest in mentoring, strong publication record, PD experience required. Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.
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Alejo Rodriguez-Fraticelli @alejofraticelli.bsky.social · 21/05/2025
Our work on lineage tracing with somatic epimutations is finally out in @nature.com! Check out the thread by @larsplus.bsky.social below. EPI-clone is a revolutionary technique for lineage tracing and it will immediately impact how we trace clones everywhere. Detailed protocols coming out soon!
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Vall d’Hebron Institute of Oncology @vhio.bsky.social · 17/04/2025
🚨 Exciting Opportunity ‼️ The #VHIO Undergraduate International Computational Oncology Award is now OPEN 🚀 Join a one-month stay at VHIO’s computational oncology labs & contribute to cutting-edge cancer research! Apply 👉 linke.to/VHIOUndergraduate25 📅 Deadline: May 23rd #SOMMVHIO #CRISVHIO
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IRB Barcelona @irbbarcelona.org · 16/04/2025
🔬Exposomal determinants of non-genetic plasticity in tumor initiation. ✍️ Davide Carra, Silvana C.E. Maas, @seoaneja.bsky.social, @direnaac.bsky.social 📰 @cp-trendscancer.bsky.social  Read more here 🔗 shorturl.at/CaicQ 📌 DOI: doi.org/10.1016/j.trecan.2025.01.010 #IRBScience 🧪
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direnaac.bsky.social @direnaac.bsky.social · 10/04/2025
Excited to share our perspective led by @davidecarra.bsky.social with @silvanamaas.bsky.social & @seoaneja.bsky.social on how non-genetic #plasticity rewires epithelial cells and their stromal/immune/microbial contextures to fuel #cancer initiation, linking exposomal histories with disease fates ⬇️
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IDIBAPS @idibaps.bsky.social · 01/04/2025
📢#JOBOFFER: Junior Group Leader in Computational Cancer Biomedicine to establish an independent research group We seek a talented scientist with expertise in: • Bioinformatics • AI • Multi-omics data integration 📅 Deadline April 14 👉https://f.mtr.cool/tyfiexzxuo
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Julio Saez-Rodriguez @juliosaezrod.bsky.social · 11/02/2025
Post-doc opening to join our lab @ebi.embl.org to develop&apply #bioinformatics and #machine-learning methods to study intra-/extra cellular networks to extract disease mechanisms from #single-cell and #spatial multiomic data - please share 🙏 : embl.wd103.myworkdayjobs.com/EMBL/job/Hin...
embl.wd103.myworkdayjobs.com
Postdoctoral fellow - Saez-Rodriguez Group
Your group Saez-Rodriguez Research Group Your supervisor Julio Saez-Rodriguez Your role As a postdoctoral fellow in the Saez Rodriguez group, you will develop and apply computational methods and tools...
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Johanna Joyce @johannajoyce.bsky.social · 26/01/2025
Rates of #cancer in #young #adults have risen dramatically in recent years - as discussed in this article.. We urgently need to invest in #research 🧪 on early-onset cancers to understand - why? www.theguardian.com/science/2025...
theguardian.com
Ultra-processed food? Forever chemicals? Declining birth rates? What’s behind rising cancer in the under-50s?
Research into the disease has never been more far-reaching, but there is little consensus as to what is causing the rocketing rates of diagnosis in young adults
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carmonasfj.bsky.social @carmonasfj.bsky.social · 09/01/2025
Open call for a Junior Group Leader position in #ComputationalOncology at Vall d'Hebron Institute of Oncology (VHIO) @vhio.bsky.social. See details below and consider applying jobs.vhio.net/en/jobs/5412... #CancerResearch
jobs.vhio.net
2024-081-01 Junior Group Leader - VHIO
Under the leadership of Josep Tabernero, VHIO is an internationally recognized cancer center. Its multidisciplinary, collaborative model drives scientific progress and innovative cancer treatments.
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Elizabeth McKenna @elizsmckenna.bsky.social · 27/11/2024
Now online in Cancer Discovery: Ancestral Differences in Anti-Cancer Treatment Efficacy and Their Underlying Genomic and Molecular Alterations - by Mei Luo, Jingwen Yang, Gordon Mills, Eytan Ruppin, Leng Han, and colleagues doi.org/10.1158/2159...
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Jose A. Seoane @seoaneja.bsky.social · 27/11/2024
www.nature.com/articles/d41...
nature.com
Let the data talk: embrace exploratory research
Open-ended research is essential to building solid hypotheses in the social sciences — without it, even the best-planned analyses can fail.
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Jose A. Seoane @seoaneja.bsky.social · 18/11/2024
Hello world!
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