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Kevin Monahan

@kevinmonahan.bsky.social
345 followers 385 following 67 posts

Gastroenterologist from @StMarksGenomics.bskyb.social with an interest in hereditary bowel cancer and occasional rants about other random things profiles.imperial.ac.uk/k.monahan

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Kevin Monahan @kevinmonahan.bsky.social · 17/03/2026
Charlie Grinstead is raising money for St Mark's Hospital Foundation by running the London Marathon - please support him! www.justgiving.com/page/charlie...
justgiving.com
Charlie's London Marathon 2026 Fundraiser for St Mark's Hospital Foundation
Help Charlie Grinstead raise money to support St Mark's Hospital Foundation
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International Society for Gastrointestinal Hereditary Tumours @insight-org.bsky.social · 06/03/2026
Another fantastic day at #InSiGHT2026 🔬 Day 3 highlighted major progress in hereditary GI cancers: From gastric & #PancreaticCancer updates to key advances in #LynchSyndrome. Great talks, global insights, and an excellent panel discussion. #GICancerPrevention #MedicalResearch
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International Society for Gastrointestinal Hereditary Tumours @insight-org.bsky.social · 07/03/2026
✨ We were truly privileged to welcome Dr Poh-Koon Koh, Senior Minister of State for Health and Manpower, Singapore, as our Guest of Honour on Day 4 of #InSiGHT2026. It was an inspiring session followed by meaningful discussions. 👏 #GuestOfHonour #AdvancingGIcancerResearch
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International Society for Gastrointestinal Hereditary Tumours @insight-org.bsky.social · 07/03/2026
That’s a wrap on #InSiGHT2026! A huge thank you to our scientific committee, organisers, speakers, participants, sponsors & partners for driving an incredible exchange of ideas. Your commitment to advancing research and care in hereditary GI cancer makes all the difference. 🌟 #InSiGHTcommunity
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International Society for Gastrointestinal Hereditary Tumours @insight-org.bsky.social · 05/03/2026
Our Young InSiGHT members are off to a strong start of #InSiGHT2026! Day 1 - Padel session full of energy & teamwork Day 2 - Breakfast session with great conversations & new connections And this is only the beginning! We can't wait to see this #InSiGHTCommunity grow 🌟 #GIcancer #YoungInSiGHT
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International Society for Gastrointestinal Hereditary Tumours @insight-org.bsky.social · 05/03/2026
Ready for Day 3 of #InSiGHT2026 ?👀 Don’t miss these exciting sessions: 🧬Session 7: Hereditary Gastric Cancer Surveillance and Management 🔬Session 8: Advances in Pancreatic Cancer Research 🧪Sessions 9 & 10: Advances in Lynch Syndrome Research #InSiGHTCommunity #GIcancer #LynchSyndrome
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Kevin Monahan @kevinmonahan.bsky.social · 26/02/2026
Improving care for Lynch syndrome patients: integrating surveillance into England’s national bowel cancer screening programme link.springer.com/article/10.1...
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Kevin Monahan @kevinmonahan.bsky.social · 05/02/2026
COLO-REACH UK = the new name for the EOCRC Research Consortium (REsearch in Early Age Colorectal cancer Hub) supporting collaboration between UK clinical academics and patients in research of bowel cancer in people below age 50 years @bowelcanceruk.bsky.social
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Trevor Graham @trevorgraham.bsky.social · 19/01/2026
Open postdoc position in our lab @icr.ac.uk to develop a cfDNA test for #early detection of colorectal #cancer in inflammatory bowel disease #IBD: jobs.icr.ac.uk/vacancies/14... It's bench-to-bedside research, translating biology of pre-cancer evolution. Funded by @bowelcanceruk.bsky.social
jobs.icr.ac.uk
Postdoctoral Training Fellow - Genomics and Evolutionary Dynimcs in Sutton | The Institute of Cancer Research
View details and apply for this Postdoctoral Training Fellow - Genomics and Evolutionary Dynimcs vacancy in Sutton. Salary: Dependent on relevant Postdoctoral experience. Durati...
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Kevin Monahan @kevinmonahan.bsky.social · 12/01/2026
Outcomes from the English National #LynchSyndrome transformation project: New diagnoses of LS have consistently increased each year from a total of 545 in 2020 to a total of 1394 in 2024 (an increase of 255% vs. a target of >50%). onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Outcomes from the English National Lynch Syndrome transformation project
The elevated cancer risk conferred by Lynch syndrome can be mitigated through preventive interventions. However, Lynch syndrome often goes underdiagnosed. The National Lynch Syndrome Transformation P...
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Kevin Monahan @kevinmonahan.bsky.social · 07/01/2026
Read about our plans to analyse the century long archive at St Mark's Hospital to understand why more young people are being diagnosed with bowel cancer @trevorgraham.bsky.social www-bbc-co-uk.cdn.ampproject.org/c/s/www.bbc....
www-bbc-co-uk.cdn.ampproject.org
Century-old tumours could reveal why more young people are getting bowel cancer - BBC News
Bowel cancer in people under the age of 50 is increasing worldwide and scientists are striving to find out why.
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International Society for Gastrointestinal Hereditary Tumours @insight-org.bsky.social · 25/11/2025
We’re proud to present the current Council members of The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), driving progress in research, collaboration, and patient care worldwide. Learn more about us👉 shorturl.at/6cyJV #Genetics #GIHealth #HereditaryGICancer #InSiGHT
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Kevin Monahan @kevinmonahan.bsky.social · 27/11/2025
Diagnostic yield of colonoscopy in Lynch Syndrome We demonstrate a high adenoma burden with distinct phenotypic and gene-specific characteristics in a UK LS population undergoing high quality surveillance fg.bmj.com/content/earl...
fg.bmj.com
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Trevor Graham @trevorgraham.bsky.social · 17/11/2025
@kevinmonahan.bsky.social & I have an open clinical #PhD position between @stmarkshospital.bsky.social and @icr.ac.uk If you're interested in the biology of pre-cancer in the bowel & want to translate biology for cancer prevention this one could be for you... funded by the brilliant #40tude
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Kevin Monahan @kevinmonahan.bsky.social · 16/11/2025
We are looking for our new Tom Smith Clinical Research Fellow in #LynchSyndrome and Early Onset ColorectalCancer with @trevorgraham.bsky.social in translational science … thanks to 40tude curing colon cancer for supporting this fellowship - get in touch! @stmarksgenomics.bsky.social @icr.ac.uk
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Kevin Monahan @kevinmonahan.bsky.social · 12/11/2025
We had the 3rd meeting of the UK EOCRC Research Consortium in beautiful Edinburgh yesterday supported by British Society of Gastroenterology (BSG) and @bowelcanceruk.bsky.social attended by over 50 UK academics - celebrating our first project funding success only 1 year after foundation
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The Irish Times @irishtimes.com · 07/11/2025
James D Watson, co-discoverer of the structure of DNA, dies aged 97
irishtimes.com
James D Watson, co-discoverer of the structure of DNA, dies aged 97
Remembered for breakthrough with Francis Crick, Watson was later ostracised by the scientific establishment over comments on race
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Kevin Monahan @kevinmonahan.bsky.social · 23/10/2025
Low Yield of Genetic Testing in Serrated Polyposis Syndrome journals.lww.com/ctg/fulltext...
journals.lww.com
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St Mark’s Hospital and Academic Institute @stmarkshospital.bsky.social · 17/10/2025
And they’re off! 🏁 👟 Elaine Burns🚶‍♀️Vs Danilo Miskovic 🏃 Our colon cancer workshop is on day 2 of ‘Frontiers’ - run or walk with our experts 🌟 (Must watch video below 👇🏻😜) Sign up to be in with a chance to participate - bit.ly/4ktsvDc @lnwh.bsky.social @kevinmonahan.bsky.social
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Kevin Monahan @kevinmonahan.bsky.social · 11/10/2025
'Everybody's unique in their own way' - Tadej Pogačar Love this guy - The true #GOAT www.cyclingnews.com/news/everybo...
cyclingnews.com
'Everybody's unique in their own way' - Tadej Pogačar plays down greatness after record-breaking fifth consecutive Il Lombardia victory
Pogačar dedicates his victory to teammate Rafał Majka
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ralucagordan.bsky.social @ralucagordan.bsky.social · 03/10/2025
I'm very pleased to announce the official publication of our lab's paper "DNA mutagenesis driven by transcription factor competition with mismatch repair" in today's issue of Cell! www.cell.com/cell/abstrac...
cell.com
DNA mutagenesis driven by transcription factor competition with mismatch repair
Competition between transcription factors and mismatch repair machinery drives localized hypermutation at regulatory elements, with implications for cancer and genome evolution.
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St Mark’s Hospital and Academic Institute @stmarkshospital.bsky.social · 03/10/2025
Can we prevent IBD? We are delighted to have Prof. Johan Burisch as one of our visiting professors for this years Frontiers congress 🙌🏻 Hear more about Prof. Burisch in the video below ⬇️ Register now - bit.ly/4ktsvDc @lnwh.bsky.social @kevinmonahan.bsky.social
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International Society for Gastrointestinal Hereditary Tumours @insight-org.bsky.social · 30/09/2025
Final Call for Abstracts – Deadline Today!⏳ Don't miss your chance to be part of the #InSiGHT2026 Biennial Meeting in #Singapore! 🌏 🗓️ Submission Deadline: 30 September 2025 ⏰ Time: Midnight (Singapore Time) / 6pm CET Submit your abstract now! insight2026.org/abstract-sub... #Genetics #GIcancer
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International Society for Gastrointestinal Hereditary Tumours @insight-org.bsky.social · 29/09/2025
🚨 Final Call: Abstract submissions for #InSiGHT2026 close TOMORROW – Sept 30! Join the global conversation on hereditary GI tumours. Submit now 👉 insight2026.org Let your research drive progress. #MedicalResearch #Genetics #GIcancer #AbstractSubmission
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Kevin Monahan @kevinmonahan.bsky.social · 27/09/2025
Our results support universal and paired somatic and germline multi-gene panels for all EOCRC patients, regardless of MMR status or family history onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
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Kevin Monahan @kevinmonahan.bsky.social · 27/09/2025
Genetic testing appears to have limited utility in SPS patients and may primarily identify those with an incidental diagnosis of Lynch syndrome pubmed.ncbi.nlm.nih.gov/41002021/
pubmed.ncbi.nlm.nih.gov
Low Yield of Genetic Testing in Serrated Polyposis Syndrome - PubMed
Genetic testing demonstrated a low diagnostic yield in this SPS cohort, suggesting undefined genetic risk or involvement of other pathophysiological factors. Therefore, genetic testing appears to have...
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Calum Gabbutt @calumgabbutt.bsky.social · 10/09/2025
Cancer is an evolutionary disease, but does knowing a cancer’s evolutionary past help predict its future? Out today in @nature, we learnt the evolution of 2000 lymphoid cancers and found it was highly correlated with clinical outcomes! (1/7) rdcu.be/eFrrc
rdcu.be
Fluctuating DNA methylation tracks cancer evolution at clinical scale
Nature - Cancer evolutionary dynamics are quantitatively inferred using a method, EVOFLUx, applied to fluctuating DNA methylation.
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Vaughn Cooper @vscooper.micropopbio.org · 21/09/2025
Lineage tracking using methylation states from longitudinal bulk sampling. Sounds 🆒 and given recent work by @trevorgraham.bsky.social and colleagues, looks real. Wondering about other applications like 🦠🧫 👉🏻News and views: www.nature.com/articles/d41... 👉🏻Paper www.nature.com/articles/s41...
nature.com
Epigenetic clues from cancer’s past foretell its future
An innovative method to trace tumour evolution using patterns of fluctuating DNA modifications could be implemented in the clinic to predict cancer progression.
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International Society for Gastrointestinal Hereditary Tumours @insight-org.bsky.social · 19/09/2025
🚨 It’s here! The Scientific Program for InSiGHT 2026 (4–7 March, Singapore 🇸🇬) is now live! 🔗 Check out the full program: insight2026.org/scientific-programme 🧬 Abstracts due 30 Sept – submit yours: insight2026.org/abstract-submission-guidelines #InSiGHT2026 #HereditaryCancer #GICancerResearch
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International Society for Gastrointestinal Hereditary Tumours @insight-org.bsky.social · 11/09/2025
🚀 Exciting news! We’re launching Young-Insight for InSiGHT members under 40. Join our first meeting to share ideas & shape the future of our community. Email admin@insight-group.org with subject “Young Insight” to get involved! 🌍✨ #InSiGHT
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Kevin Monahan @kevinmonahan.bsky.social · 06/09/2025
The registries’ combined experiences underscore the critical need for integrated, culturally sensitive strategies combining genetic testing, enhanced surveillance, and family-based management to improve outcomes #Polyposis #LynchSyndrome link.springer.com/article/10.1...
link.springer.com
Comparative insight: hereditary colorectal cancer registries in Iran, Singapore, and South Africa - Familial Cancer
This study compares three hereditary colorectal cancer (CRC) registries—the Iranian Hereditary Colorectal Cancer Registry (IHCCR), the Singapore Polyposis Registry (SPR), and the University of Cape To...
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International Society for Gastrointestinal Hereditary Tumours @insight-org.bsky.social · 08/08/2025
📢 Join us in Singapore for the InSiGHT Biennial Meeting, 4–7 March 2026! 🔹 Abstract Deadline: 20 Sept 2025 🔹 Early Bird: 10 Jan 2026 Link ➡️ insight2026.org Let’s advance hereditary GI cancer research together! #InSiGHT2026 #MedicalResearch #GItumours
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Kevin Monahan @kevinmonahan.bsky.social · 11/08/2025
Come and work with us! We are seeking a Regional #LynchSyndrome Nursing Lead band 8 for 12 months to provide teaching and training across North London #Genomics apps.trac.jobs/job-advert/7...
apps.trac.jobs
Regional Lynch Syndrome Nursing Lead | Job advert | Trac
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Kevin Monahan @kevinmonahan.bsky.social · 21/07/2025
Please follow @insight-org.bsky.social on BlueSky and join us for insight2026.org in Singapore, abstract submission now live!
insight2026.org
InSiGHT 2026
Register Now Submit AbstractSubmit your abstracts by 20 September 2025.For Inquiries: Please feel free to email us directly:info@insight2026.orgregistration@insight2026.orgabstract@insight2026.orgGol...
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Kevin Monahan @kevinmonahan.bsky.social · 21/07/2025
Please follow @insight-org.bsky.social on BlueSky and join us for insight2026.org in Singapore, abstract submission now live!
insight2026.org
InSiGHT 2026
Register Now Submit AbstractSubmit your abstracts by 20 September 2025.For Inquiries: Please feel free to email us directly:info@insight2026.orgregistration@insight2026.orgabstract@insight2026.orgGol...
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International Society for Gastrointestinal Hereditary Tumours @insight-org.bsky.social · 21/07/2025
👋 Welcome to InSiGHT on BlueSky! We are a global community of researchers, clinicians, and scientists dedicated to advancing the understanding, diagnosis, and management of hereditary GI cancers. Follow us for updates on scientific advances, clinical guidelines, and upcoming events. #InSiGHT
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Kevin Monahan @kevinmonahan.bsky.social · 13/07/2025
Abstract submission is now open for #Insight2026 ! Deadline 7th September #LynchSyndrome #Polyposis #EOCRC @soniakupfer.bsky.social @swatipatelmd.bsky.social @cgaigc.com @stmarksgenomics.bsky.social @plsdatabase.bsky.social insight2026.org
insight2026.org
InSIGHT 2026
REGISTRATION NOW OPEN Register NowCall for Abstracts Now Open! Submit Your AbstractWelcome MessageWelcome to Singapore, Selamat Datang, 欢迎, வருக வருக. On behalf of InSiGHT, we are delighted to invite....
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Kevin Monahan @kevinmonahan.bsky.social · 07/07/2025
Mainstreaming clinicians in colorectal and Gynae teams… think about this study!
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Kevin Monahan @kevinmonahan.bsky.social · 01/07/2025
Join us 19-21 November for a bigger and better St Mark's Frontiers in Colorectal Disease Meeting, in a beautiful venue in King's Cross London! Extremely good value, with hybrid options @stmarkshospital.bsky.social sayso.health/events/front...
sayso.health
St Mark's Frontiers 2025
Register now for our Annual Frontiers in Colorectal and Intestinal Disease Congress, from the 19th–21st November 2025.
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Kevin Monahan @kevinmonahan.bsky.social · 01/07/2025
Join us 19-21 November for a bigger and better St Mark's Frontiers in Colorectal Disease Meeting, in a beautiful venue in King's Cross London! Extremely good value, with hybrid options @stmarkshospital.bsky.social sayso.health/events/front...
sayso.health
St Mark's Frontiers 2025
Register now for our Annual Frontiers in Colorectal and Intestinal Disease Congress, from the 19th–21st November 2025.
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Kevin Monahan @kevinmonahan.bsky.social · 26/06/2025
Missed opportunities: Germline testing following tumor sequencing pubmed.ncbi.nlm.nih.gov/40554180/
pubmed.ncbi.nlm.nih.gov
Missed opportunities: Germline testing following tumor sequencing - PubMed
In this cohort, 60 % of the eligible population by ESMO criteria did not receive GT, most commonly due to lack of referral (over 2/3 of patients). Further, 50 % of patients not referred for GT had mut...
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Kevin Monahan @kevinmonahan.bsky.social · 24/06/2025
Great to meet up with Pam from Lynch Syndrome UK at BSG Live 2025 in Glasgow today! @thepoodoctor.bsky.social @lynchsyndromeuk.bsky.social @stmarksgenomics.bsky.social
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Kevin Monahan @kevinmonahan.bsky.social · 10/06/2025
On behalf of InSiGHT, we are delighted to welcome you to the #InSiGHT2026 meeting in Singapore, taking place from 4 – 7 March 2026 #LynchSyndrome #Polyposis @cgaigc.com @stmarksgenomics.bsky.social insight2026.org
insight2026.org
InSIGHT 2026
REGISTRATION NOW OPEN Register NowCall for Abstracts Now Open! Submit Your AbstractWelcome MessageWelcome to Singapore, Selamat Datang, 欢迎, வருக வருக. On behalf of InSIGHT, we are delighted to invite....
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Kevin Monahan @kevinmonahan.bsky.social · 10/06/2025
On behalf of InSiGHT, we are delighted to welcome you to the #InSiGHT2026 meeting in Singapore, taking place from 4 – 7 March 2026 #LynchSyndrome #Polyposis @cgaigc.com @stmarksgenomics.bsky.social insight2026.org
insight2026.org
InSIGHT 2026
REGISTRATION NOW OPEN Register NowCall for Abstracts Now Open! Submit Your AbstractWelcome MessageWelcome to Singapore, Selamat Datang, 欢迎, வருக வருக. On behalf of InSIGHT, we are delighted to invite....
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Trevor Graham @trevorgraham.bsky.social · 07/06/2025
Lovely new paper from @leedham-simon.bsky.social dissecting epithelium-microenvironment crosstalk through BMP & wnt signalling in the intestine. Inhibition of BMP antagonist GREM1 may forestall polyp formation in Hereditary Mixed Polyposis Syndrome (HMPS). www.nature.com/articles/s41...
nature.com
Epithelial GREMLIN1 disrupts intestinal epithelial-mesenchymal crosstalk to induce a wnt-dependent ectopic stem cell niche through stromal remodelling - Nature Communications
The authors show that aberrant epithelial GREM1 expression remodels intestinal stroma to form ectopic stem cell niches in mice. Anti-GREM1 reversed these changes, highlighting a potential strategy for...
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Kevin Monahan @kevinmonahan.bsky.social · 08/06/2025
In Our Scope of Practice: Genetic Risk Assessment and Testing for GI Cancers and Polyposis in Gastroenterology - @amergastroassn.bsky.social @soniakupfer.bsky.social www.gastrojournal.org/article/S001...
gastrojournal.org
In Our Scope of Practice: Genetic Risk Assessment and Testing for GI Cancers and Polyposis in Gastroenterology
Gastrointestinal (GI) clinicians are a critical touchpoint for individuals at risk for genetic and familial syndromes that increase risk of colorectal, gastric and pancreatic cancer. While advances in...
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Kevin Monahan @kevinmonahan.bsky.social · 05/06/2025
Are you an #endoscopist? Interested in assessing & managing advanced #colonic #polyps? Can we improve our #training in this? @stmarkshospital.bsky.social We are keen to hear your views. Please complete this short survey @esge-news.bsky.social docs.google.com/forms/d/e/1F...
gbr01.safelinks.protection.outlook.com
Optical assessment of advanced colorectal polyps survey and quiz
Thank you for undertaking this survey and quiz. It should take 5-10 minutes to complete. All responses are completely anonymous. Please only respond once.
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CGA-IGC @cgaigc.com · 03/06/2025
Led by our 2024 president, Bryson Katona, MD, PhD, our Executive Council developed a 3-year strategic plan to guide our society's future We’re proud to share this as we mark our 30th anniversary. Explore the plan 👉https://link.springer.com/article/10.1007/s10689-025-00473-9 #HereditaryGICancer
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Kevin Monahan @kevinmonahan.bsky.social · 20/05/2025
If you are a from a #colorectalcancer #MDT and offering mainstream #genetic testing to your own patients then please consider joining Detect2 which may half your workload! We’re delighted to have recruited our first 3 patients… get in touch or click below for more www.detect-2.co.uk
detect-2.co.uk
DETECT-2
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