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David Seki

@sekid.bsky.social
140 followers 146 following 6 posts

Senior PostDoc at Cluster of Excellence “Microbiomes drive Planetary Health“ Human Gut Microbial Ecology, Pharmacology, Neonatal Gut-Immune-Brain Axis Development.

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Reposted by David Seki
Hall Lab @halllab.bsky.social · 11/09/2025
Excited to share our @cp-cellhostmicrobe.bsky.social led by Magda showing how Bif has co-evolved with different animal hosts 🐒🐭🐷🐦 Key takeaways: 🔹 Host ancestry + diet shape Bif evolution 🔹 Mammals enriched for carb-busting enzymes 🔹 Untapped diversity in non-human hosts = new probiotic potential
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Reposted by David Seki
Nature @nature.com · 06/09/2025
Nature research paper: Supervised learning in DNA neural networks go.nature.com/4mOb9lH
go.nature.com
Supervised learning in DNA neural networks - Nature
DNA molecules can be programmed to autonomously carry out supervised learning in vitro, with the system learning to perform pattern classification from molecular examples of inputs and desired responses.
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Reposted by David Seki
Alex Loy @loyteam.bsky.social · 27/08/2025
📢 New paper in @nature.com Microbes rock 🎸🤘 with sulfide and iron minerals I am very excited to share our recent study, which describes a previously unknown microbial energy metabolism ⚡⚡⚡🦠🧫⚡⚡⚡ 🆕 Microbial iron oxide respiration coupled to sulfide oxidation - MISO www.nature.com/articles/s41...
nature.com
Microbial iron oxide respiration coupled to sulfide oxidation - Nature
Genomic and biochemical analyses of prokaryotic sulfur metabolism identify diverse microorganisms with the capacity to oxidize sulfide using iron(iii).
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Reposted by David Seki
Emmanuele Severi @emmseveri.bsky.social · 21/08/2025
www.nature.com/articles/s41... #microsky
nature.com
A novel bacterial protein family that catalyses nitrous oxide reduction - Nature
Cultivation of tropical soil microorganisms combined with physiological experiments and bioinformatics analyses identify a family of clade III lactonase-type nitrous oxide reductases with low sequence...
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Reposted by David Seki
Nature @nature.com · 01/08/2025
Two vaccine candidates using mRNA technology elicit a potent immune response against HIV go.nature.com/4ov7WZI
go.nature.com
mRNA vaccines for HIV trigger strong immune response in people
Results from early-stage trial show that 80% of participants who received one of two HIV vaccine candidates produced antibodies against viral proteins.
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Reposted by David Seki
Nature Portfolio @natureportfolio.nature.com · 31/07/2025
An analysis in Nature Ecology & Evolution shows that near-national-scale losses of bird diversity greatly exceed losses recorded at the local scale in Colombia, suggesting that extrapolations from local studies will severely underestimate biodiversity losses. go.nature.com/3HbRv3s 🧪
This is figure 1, which shows the methodological pipeline.
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David Seki @sekid.bsky.social · 09/04/2025
Excited to finally share results from my first post-doc @halllab.bsky.social 🫡 E.coli commonly occurs in infant gut microbiota, yet its role during healthy development has been disregarded. In our pre-print, we reveal its fundamental involvement in HMO-degradation. www.biorxiv.org/content/10.1...
biorxiv.org
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Reposted by David Seki
Daria Van Tyne @dariavantyne.bsky.social · 21/03/2025
Excited to share our latest, out today in @naturemicrobiol.bsky.social Bacteriocin production facilitates nosocomial emergence of vancomycin-resistant Enterococcus faecium www.nature.com/articles/s41... @idpittstop.bsky.social
nature.com
Bacteriocin production facilitates nosocomial emergence of vancomycin-resistant Enterococcus faecium - Nature Microbiology
Genomic and functional analyses of healthcare-associated vancomycin-resistant Enterococcus faecium reveal that bacteriocin T8 is enriched in emergent lineages and provides a competitive advantage in v...
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Reposted by David Seki
Anthony Shiver @anthonyshiver.bsky.social · 13/03/2025
Interested in the influence of the infant microbiome on health? Quickly interrogating non-model organisms using omic approaches? A new publication, describing genome-scale resources in bifidobacteria, is now available online: doi.org/10.1016/j.ce... #microbiome #microsky
Silhouettes of infant, mouse, chick, and bacteria.
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Reposted by David Seki
Di Jiang @dijiang319.bsky.social · 24/01/2025
This week @science.org Sarfatis, Moffitt et al. from @bostonchildrens.bsky.social @harvardmed.bsky.social @broadinstitute.org Highly multiplexed spatial transcriptomics in bacteria | Science www.science.org/doi/10.1126/... #microsky #microbial #microbiology #genomics #transcriptomic 🦠🧫
science.org
Highly multiplexed spatial transcriptomics in bacteria
Single-cell decisions made in complex environments underlie many bacterial phenomena. Image-based transcriptomics approaches offer an avenue to study such behaviors, yet these approaches have been hin...
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Reposted by David Seki
Samir Giri @isamirgiri.bsky.social · 13/01/2025
Excited to share our opinion piece with the KC Huang Lab. Check it out here: Harnessing gut microbial communities to unravel microbiome functions doi.org/10.1016/j.mi... @typaslab.bsky.social
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Reposted by David Seki
Alexandre Almeida @alexmsalmeida.bsky.social · 10/01/2025
Delighted to share the first peer-reviewed paper from our team @camvetschool.bsky.social where we investigate the ecological dynamics of Enterobacteriaceae in the human gut #microbiome: www.nature.com/articles/s41... @naturemicrobiol.bsky.social
nature.com
Ecological dynamics of Enterobacteriaceae in the human gut microbiome across global populations - Nature Microbiology
Assessing more than 12,000 metagenomic samples from across the world using computational approaches, the authors determined interactions between species that co-colonize or co-exclude Enterobacteriace...
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Reposted by David Seki
Jatin Nagpal @jatinnagpal.bsky.social · 10/01/2025
Host metabolism balances microbial regulation of bile acid signalling | @nature.com www.nature.com/articles/s41...
nature.com
Host metabolism balances microbial regulation of bile acid signalling - Nature
A family of host-derived bile acid–methylcysteamine conjugates functions as FXR antagonists, forming part of a microbiota-dependent metabolic network that regulates FXR-dependent physiology.
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Reposted by David Seki
Hall Lab @halllab.bsky.social · 11/01/2025
1/ 🚨 New preprint alert! 🚨 We’re thrilled to share our latest work exploring microbiome & genomic #Bifidobacterium co-evolutionary & functional signatures across diverse animal hosts. This has been a long time coming, & huge credit to Magda for her incredible hard work as first author! 🐾✨👇
doi.org
Host-specific microbiome and genomic signatures in Bifidobacterium reveal co-evolutionary and functional adaptations across diverse animal hosts
Animal hosts harbour divergent microbiota, including various Bifidobacterium species and strains, yet their evolutionary relationships, and functional adaptions remain understudied. By integrating tax...
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Reposted by David Seki
Hall Lab @halllab.bsky.social · 06/12/2024
🚨 PhD Opportunity @halllab.bsky.social! 🔬 Decoding Early Life Microbiota & Host Interactions 🧬 Ideal for those with bioinformatics/microbiome experience 🌍 Open to international candidates (MSCA mobility rules apply). 📅 Deadline: 18th Dec 🌐 Apply now: www.findaphd.com/phds/project...
findaphd.com
Decoding Early Life Microbiota and Host Interactions at University of Birmingham on FindAPhD.com
PhD Project - Decoding Early Life Microbiota and Host Interactions at University of Birmingham, listed on FindAPhD.com
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