The authors present a framework to isolate condensed marker gene signatures by requiring both conserved cell-type specificity and conserved expression across multi-species scRNA-seq datasets. Bone mar...

Eight integrated mutational footprints collectively explain the mutational processes in 85% of primary prostate cancer genomes.

With funding from the German Research Foundation’s (DFG) Heisenberg Program, DKFZ researcher Aurélie Ernst aims to investigate how massive changes in the genome contribute to the development of cancer...

Three researchers at the German Cancer Research Center (DKFZ) have each been awarded a Starting Grant from the European Research Council (ERC) this year. Daniel Kirschenbaum, Lena Kutscher, and Michael Scherer impressed the ERC with their innovative research approaches to fundamental questions in cancer medicine. With the funding, they plan to investigate why certain brain tumors occur more frequently in boys than in girls, how brain tumors suppress the immune system, and which epigenetic characteristics make cancer cells resistant to drugs.

Gleich drei Forschende am Deutschen Krebsforschungszentrum (DKFZ) erhalten dieses Jahr einen Starting Grant des Europäischen Forschungsrats (ERC). Daniel Kirschenbaum, Lena Kutscher und Michael Scherer überzeugten mit innovativen Forschungsansätzen zu grundlegenden Fragen der Krebsmedizin. Mit den Fördermitteln wollen sie untersuchen, warum bestimmte Hirntumoren bei Jungen häufiger auftreten als bei Mädchen, wie Hirntumoren die Immunabwehr ausbremsen und welche epigenetischen Eigenschaften Krebszellen resistent gegen Medikamente machen.

Three researchers at the German Cancer Research Center (DKFZ) have each been awarded a Starting Grant from the European Research Council (ERC) this year. Daniel Kirschenbaum, Lena Kutscher, and Michae...

Background Cell state-specific gene expression programs emerge from the interplay between cis-regulatory elements (CREs), such as enhancers, and transcription factors (TFs). Massively parallel reporte...

Ein Team unter Leitung von Forschenden aus dem Deutschen Krebsforschungszentrum (DKFZ) und dem Stammzell-Institut HI-STEM* hat einen vielversprechenden neuen Ansatz zur Behandlung von fortgeschrittene...

Descubre los proyectos y avances clave en investigación contra el cáncer que cuentan con el apoyo de la Asociación Española Contra el Cáncer en 2025

dplyr but make it bussin fr fr no cap. Contribute to hadley/genzplyr development by creating an account on GitHub.

IDH-mutant gliomas represent a subtype of diffuse gliomas that primarily affect patients in early to mid-adolescence. These tumors are classified into three distinct CNS WHO grades of malignancy. Accu...

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Ein interdisziplinäres Team aus Wissenschaftlerinnen und Wissenschaftlern vom Berlin Institute of Health in der Charité (BIH), vom Max Delbrück Center, dem Deutschen Krebsforschungszentrum (DKFZ), dem...

Leukemia - DNA demethylation-mediated downregulation of MNX1 in acute myeloid leukemia