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Zhang, Chen, and colleagues present Thor, a platform that turns spot-level spatial transcriptomics into single-cell gene maps using the paired histology image, without using single-cell RNA-seq data.…

Announcing taxburst for metagenome taxonomy!

Food-specific immunoglobulin E (IgE) triggers life-threatening anaphylaxis; however, for unclear reasons, some people with food-specific IgE are asymptomatic upon allergen consumption. We studied stra...

New tool combines biological knowledge with machine learning to help researchers extract meaningful insights from complex omics data.

This opinion piece discusses the Bioconductor project for open-source bioinformatics and the engineering concepts underlying its effectiveness to date…

Fine tune which notifications you receive, opt-in to receive push notifications from specific accounts, and receive notifications when someone likes or reposts posts you’ve reposted.

Women are more likely to take on behind-the-scenes duties at work—extra tasks like onboarding or event planning—and it's hurting their careers. Here's how to say no.

Nature - Concern rises among researchers after agency officials ask for a list of projects funded to study the jabs.

Germinal centre B cells modify their mutation rate to preserve high-affinity receptors, thereby safeguarding high-affinity B cell lineages and enhancing the outcomes of antibody affinity maturation.

NicheCompass is a graph variational autoencoder approach for identifying cellular niches defined by cell–cell communication and other interactions, applicable to a broad variety of spatial multi-omic ...

Your group Saez-Rodriguez Research Group Your supervisor Julio Saez-Rodriguez Your role As a postdoctoral fellow in the Saez Rodriguez group, you will develop and apply computational methods and tools...

The authors show that brain inflammation in COVID-19 correlates with viral load, systemic inflammation and virus-sensing pattern recognition receptors. Microglial dysfunction occurs at sites of vascular inflammation with myelin injury and synapse loss.

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TSLP acts on Tregs to control allergic airway inflammation.

In this review we summarise current understanding of immune changes associated with oral immunotherapy (OIT), as established through molecular profiling of the transcriptome. Changes observed during ...