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Bob Salmond

@salmondleeds.bsky.social
2.1K followers 850 following 46 posts

Associate Professor at University of Leeds. Interested in T cell signalling, metabolism and tumour immunology.

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Reposted by Bob Salmond
UCSF @ucsanfrancisco.bsky.social · 26/09/2026
UCSF’s Kevan Shokat, PhD, just won the $1M Stephenson Global Prize for research in pancreatic cancer. He cracked KRAS, a cancer driver long considered “undruggable.” Drugs built on his work now treat lung and pancreatic cancer. ow.ly/UYuY50ZRSXg
Middle-aged man in a blue lab coat smiling while seated in a scientific laboratory setting.Hand wearing black glove holding five small glass vials with various colored liquids, including pink and orange hues.
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Bob Salmond @salmondleeds.bsky.social · 04/09/2026
Super interesting!!
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Prof Christina Pagel @chrischirp.bsky.social · 31/07/2026
🧵On @thenewsagents.co.uk yesterday, school closures and the lab leak theory were offered as two examples of legitimate questions that were hard to ask. Both have in fact been asked constantly since 2020. But here's a thread on why I think they were wrong and dangerous on school closures 1/12
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The Editorial Board @editorialboard.bsky.social · 31/07/2026
A thread on how heroes like Dr. Anthony Fauci make Trump and the Republicans look like criminals by comparison. That's why they tried to destroy his good name. That's the story.
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Rebecca Drummond 🍄 @therad-lab.bsky.social · 30/06/2026
I wrote a mini review about host-fungal interactions, reflecting on what I've learned since starting my lab. A few bits of advice in here for new PIs! Check it out here: journals.asm.org/doi/10.1128/... #immunosky #microsky 🧪 🍄
journals.asm.org
Hidden battles: dissecting host–fungal interactions and immune heterogeneity in infection outcomes | mSphere
When I began my research group in 2018, I was determined to use an interdisciplinary approach in our work, which focuses on the immunology of fungal meningitis and brain infections. In my original mSp...
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The Seattle Times @seattletimes.com · 06/06/2026
Steven Kahn, director of the UW Diabetes Research Center, was removed by police from a national conference as he and others handed out copies of an editorial.
seattletimes.com
UW diabetes researcher removed from conference by police
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Carl T. Bergstrom @carlbergstrom.com · 06/06/2026
Here's the article. diabetesjournals.org/care/article...
diabetesjournals.org
Misguided Brushes of a Pen Continue to Dismantle and Destroy Biomedical Research in the United States: We Can No Longer Afford Complacency and Fear. We Must All Act Now!
The opinions expressed in this editorial are the personal views of the authors (S.E. Kahn, C.A.M. Anderson, J.B. Buse, and E. Selvin) and do not represent
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Nature @nature.com · 10/05/2026
Obituary: J Craig Venter (1946-2026) maverick biotechnologist who sequenced the human genome go.nature.com/4tk1Psp
go.nature.com
J. Craig Venter obituary: maverick biotechnologist who sequenced the human genome
Nature - The entrepreneur was also a pioneer of synthetic biology.
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Tim Bale @timbale.bsky.social · 05/05/2026
As these things go - and it obviously won't impact on his diehard fans - this, from the Tories, is actually quite an impressive effort.
youtube.com
Nigel Farage Doesn't Want You To Watch This Video
YouTube video by Conservatives
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Oded Rechavi @odedrechavi.bsky.social · 03/04/2026
Every PI
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Bob Salmond @salmondleeds.bsky.social · 22/01/2026
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Bob Salmond @salmondleeds.bsky.social · 17/12/2025
UK to rejoin Erasmus. Great news www.bbc.co.uk/news/live/c4...
bbc.co.uk
Erasmus live updates: Scheme to return for UK students from 2027
British students will be will be able to spend a year studying at EU universities without paying extra fees, and vice versa for European students.
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Reposted by Bob Salmond
Walker Bragman @walkerbragman.bsky.social · 13/12/2025
NEW: @origgio.bsky.social and I went back and fact checked more of the misleading and false narratives in Plague of Corruption, the anti-vax documentary narrated by Liam Neeson. For more of this kind of journalism, support @accountabilityji.bsky.social www.importantcontext.news/p/fact-check...
importantcontext.news
Fact Checking the Liam Neeson-Narrated Anti-Vax Documentary
The false and misleading narratives in Plague of Corruption revisited.
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Bob Salmond @salmondleeds.bsky.social · 05/12/2025
Very much enjoyed BSI Annual Congress in Liverpool. Excellent programme, outstanding speakers and great chance to catch up with a lot of familiar faces #BSI25
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Bob Salmond @salmondleeds.bsky.social · 19/11/2025
What a game. I was an undergrad the last time we were at the WC, been a long time coming!
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Clive McKimmie @clive-mckimmie.bsky.social · 03/11/2025
New paper out in iScience @cellpress.bsky.social We show that #sand_fly biting reprograms skin fibroblasts, making them more permissive to virus infection => #fibroblasts aren’t bystanders, they help define severity/clinical outcome to infection AND #vector biting is key 👉 doi.org/10.1016/j.is...
Diagram showing how sand fly saliva changes fibroblast state to promote arbovirus infection.
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Zoe Gardner @zoejardiniere.bsky.social · 18/10/2025
When was the last time you heard a politician in the media asked anything like- -How will you make sure asylum seekers can reach the UK safely & refugees are protected? -How will you make sure people coming to this country to work or study are treated equally & with respect? I cannot remember.
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Rebecca Drummond 🍄 @therad-lab.bsky.social · 09/10/2025
Very pleased to share the latest data from the lab, out today in @naturecomms.nature.com ! We show 🧠 infiltrating CD4 Tcells drive inflammatory #microglia proliferation during fungal meningitis, contributing towards early clinical symptoms www.nature.com/articles/s41...
nature.com
Brain-infiltrating CD4 T cells drive inflammatory microglia proliferation during cryptococcal meningitis in mice
Nature Communications - Cryptococcal meningitis is a common infection in patients with compromised CD4 T cell function. Using a CD4 T cell activation tracking mouse the authors show the...
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Prof Gavin Yamey MD MPH @gavinyamey.bsky.social · 09/10/2025
“A study, published on Wednesday in the New England Journal of Medicine, showed that last season’s 2024–2025 mRNA COVID vaccines reduced people’s risk of emergency department visits by 29%, their risk of hospitalizations by 39% & their risk of death by 64%” Benefits were seen even if 0 risk factors
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Klaus Okkenhaug @klausokken.bsky.social · 06/10/2025
Nobel prize for Tregs! www.nobelprize.org/prizes/medic...
nobelprize.org
Nobel Prize in Physiology or Medicine 2025
The Nobel Prize in Physiology or Medicine 2025 was awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”
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KOJAMF🤘🖤🤘 @kojamf.bsky.social · 05/10/2025
Dr. Jane Goodall filmed an interview with Netflix in March 2025 that she understood would only be released after her death.
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Dr Vanessa @hpsvanessa.bsky.social · 04/10/2025
I only ever heard second-hand from my German relatives what the 1930s were like but it sounded like this. You see the story, it feels wrong, but everyone else around you is just carrying on, shopping, working, going to the cinema. So you do the same. Keep your head down, maybe this is fine? Normal?
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Denis Wirtz @deniswirtz.bsky.social · 30/09/2025
We have developed hyper-migratory CAR T cells that alleviate ovarian cancer metastatic burden and improve prognosis. We transduce synthetic modular "velocity" receptors that promote fast and deep infiltration of CAR T cells into mets in the liver. More here: www.biorxiv.org/content/10.1...
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Bob Salmond @salmondleeds.bsky.social · 21/09/2025
Latest preprint from us
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Audrey John MD PhD @odomjohnlab.bsky.social · 05/08/2025
To say that "the data show these vaccines fail" in regards to the mRNA plaform is unforgivable. For those of you that don't remember - this is the data from a SINGLE dose. In December 2020. So good I cried in grateful tears.
Kaplan Meier curve showing efficacy of mRNA vaccine against COVID-19
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Jake Scott, MD @jakescottmd.bsky.social · 05/08/2025
JUST IN: HHS shuts down BARDA mRNA vaccine program Scrapping the fastest platform we have is a reckless move rooted in a fundamental misunderstanding of vaccinology. No respiratory vaccine blocks all infections. mRNA vaccines have saved millions of lives. www.hhs.gov/press-room/h...
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Clive McKimmie @clive-mckimmie.bsky.social · 06/08/2025
We knew this deeply misguided man was bad news, but now his actions threaten us all. RNA-based vaccines are safe, effective at preventing disease, and can be rapidly manufactured at scale. Just as the threat of infectious disease increases, we remove our best defence. www.bbc.co.uk/news/article...
bbc.co.uk
RFK Jr cancels $500m in mRNA vaccine development in the US
Since taking office, the vaccine sceptic has made a number of changes to how vaccines are regulated.
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Rep. Jamie Raskin @raskin.house.gov · 05/08/2025
Former Mossad, Shin Bet and IDF leaders join most of the world in demanding an immediate end to the Gaza war, saying it’s now an unjust, immoral and futile war of destruction guided by 'messianic and extremist goals' and threatening ‘the loss of Israel's security and freedom.’ It must end now.
haaretz.com
'A futile war': Former Israeli security chiefs warn current Gaza war has no strategy
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Roychoudhuri Lab @roychoudhurilab.bsky.social · 05/08/2025
Please sign this Parliamentary petition calling for comprehensive trade sanctions on Israel - the limited sanctions on specific members of the Israeli Government by the UK do not go far enough: petition.parliament.uk/petitions/72...
petition.parliament.uk
Petition: Review all trade ties with Israel, suspend 2030 roadmap & impose trade sanctions
We call on the Government to review existing trade ties with Israel, suspend the 2030 Roadmap for UK-Israel bilateral relations and impose trade sanctions upon Israel.
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Iannacone Lab @iannaconelab.bsky.social · 30/06/2025
1/ 🚨 Hot off the press in Nature Immunology: CD4⁺ T cells can license Kupffer cells to rescue dysfunctional CD8⁺ T cells in the liver. Hepatitis B virus (HBV) infection is just the proving ground—this is a paradigm shift in tissue immunity. www.nature.com/articles/s41... 🧵(1/11)
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Prof Christina Pagel @chrischirp.bsky.social · 18/05/2025
A more personal substack post today about the first refugee I hosted through @refugeesathome.bsky.social . It's not something I talk about much but I felt I needed to write something in response to the increasingly hostile environment for refugees. christinapagel.substack.com/p/the-path-t...
christinapagel.substack.com
The path to citizenship the UK has choked off - to our detriment
A story of hope and anger and one man called B.
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lindsay berger sacks @lindsaybergersacks.bsky.social · 16/05/2025
Pres, Gagliardi, of the 🇺🇸 Federation of Musicians: “We will not remain silent as 2 of our members Bruce Springsteen & Taylor Swift r singled out & personally attacked by the POTUS. S&S r not just brilliant musicians, they r role models & inspirations 2 millions of ppl in the US & across the🌍” 👏🏼👏🏼👏🏼👏🏼👏🏼
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Steve Griffin @profstevegriffin.bsky.social · 09/05/2025
My daughter receives world-class care from the paediatric T1D team at @LeedsHospitals It's not a service to be cut. It's the standard of care that the entire #NHS should be aiming for This is not the way forward @wesstreeting.bsky.social @rachelclarke.bsky.social www.bbc.co.uk/news/article...
bbc.co.uk
NHS cuts: Diabetes care, talking therapies and rehab at risk
Diabetes care, rehab centres, end-of-life services and talking therapies at risk in England.
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Stan Oklobdzija @stano.bsky.social · 09/05/2025
"Masked security forces captured an opposition leader in the coastal province of New Jersey as regime officials continue their months-long crack-down against pro-democracy elements in the embattled United States. The arrest comes as the regime issued calls for summary detentions without trial."
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Robert Reich @rbreich.bsky.social · 01/05/2025
Increase in productivity since 1979: 86% Increase in hourly pay since 1979: 31% Just so happens that ~25% of workers were unionized in 1979. Today? 10%. As unions declined, the super-rich have taken a larger share of wealth generated by labor. We must build back union power.
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Linda Sinclair @lindavsinclair.bsky.social · 26/04/2025
Our review on Protein Synthesis and Metabolism in T cells is out @annualreviews.bsky.social @cantrell-lab.bsky.social Protein Synthesis and Metabolism in T Cells #proteomics #immunometabolism #Tcells www.annualreviews.org/content/jour...
annualreviews.org
Protein Synthesis and Metabolism in T Cells | Annual Reviews
T lymphocytes are essential for immune responses to pathogens and tumors. Their ability to rapidly clonally expand and differentiate to effector cells following infection, and then to curb effector fu...
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Bob Salmond @salmondleeds.bsky.social · 26/04/2025
Congrats @lindavsinclair.bsky.social on your (and Doreen’s) Annual Review. A must read. www.annualreviews.org/content/jour...
annualreviews.org
Protein Synthesis and Metabolism in T Cells | Annual Reviews
T lymphocytes are essential for immune responses to pathogens and tumors. Their ability to rapidly clonally expand and differentiate to effector cells following infection, and then to curb effector fu...
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Dr. Lisa Reynolds @drlarey.bsky.social · 25/04/2025
Did you know that there are eosinophils in the thymus? Are you curious about what they might be doing there? If so please have a read of our latest review, where Dominique Gatti has summarized the status of the field and outstanding questions on this topic! :) academic.oup.com/jleukbio/art...
academic.oup.com
Thymic eosinophils: What are you doing here?
Eosinophils are present in thymus of humans and mice, and the heterogeneity of thymic eosinophil populations, their functional capacities, and the factors
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Mark Carney @mark-carney.bsky.social · 16/04/2025
Thank you, Neil, for your support. Keep on Rockin’ in the Free World. tinyurl.com/yzmj52yj
tinyurl.com
Neil Young Archives
NYA contains the complete archives of Neil Young. The site is designed for a chronological exploration of artist output including music, books, films, & videos. Music is streamed in high-res with Xstr...
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Adrian Liston @labliston.bsky.social · 14/04/2025
Our @natrevimmunol.bsky.social review with @abhishekgarglab.bsky.social, @deadoc80.bsky.social and Kellie Smith is out! We attempt to integrate the data on CD8 T cell dysfunction into a new framework of hypofunctionality in cancer and chronic infections! www.nature.com/articles/s41...
nature.com
The diversity of CD8+ T cell dysfunction in cancer and viral infection - Nature Reviews Immunology
Beyond exhaustion, CD8+ T cells can adopt various dysfunctional states, including tolerant, anergic, senescent, ignorant and dying states, that compromise their ability to eradicate viruses or tumours...
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American Society of Hematology @ash.hematology.org · 03/04/2025
Stand up with ASH and #Fight4Hematology! 🩸💪 As executive orders threaten hematologic research and care of patients, ASH has created a new #Fight4Hematology Action Hub to keep you informed and involved. Learn how to protect #hematology: www.hematology.org/a... #HemeSky #MedSky
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Roychoudhuri Lab @roychoudhurilab.bsky.social · 05/03/2025
Thrilled to share new work led by @jieyang437.bsky.social in the lab published today in @Nature. We find that Aspirin prevents metastasis by releasing T cells from immune suppression by platelet TXA2. @Cambridge_Uni @CRUKCamCentre rdcu.be/eci1U
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Bob Salmond @salmondleeds.bsky.social · 01/03/2025
Exciting new paper from Linda Sinclair and colleagues. Check it out!
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Jon Cooper @joncooper-us.bsky.social · 28/02/2025
Pass it on. #StandWithUkraine
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Ursula von der Leyen @vonderleyen.ec.europa.eu · 28/02/2025
Your dignity honors the bravery of the Ukrainian people. Be strong, be brave, be fearless. You are never alone, dear President Zelenskyy. We will continue working with you for a just and lasting peace.
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James O’Brien @mrjamesob.bsky.social · 28/02/2025
He is not just appeasing Putin, he is aligned with him. And every single client journalist, political shill & public/online cheerleader on both sides of the Atlantic is too. Against Zelensky. Against Ukraine. Against freedom. Against the most basic tenets of decency.
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Shaun Lintern @shaunlintern.bsky.social · 28/02/2025
You can send donations yourself direct to ukraine here: war.ukraine.ua/donate/ #SlavaUkraïni
war.ukraine.ua
Donate to Ukraine’s defenders
The National Bank of Ukraine has decided to open a special fundraising account to support the Armed Forces of Ukraine.
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Dr Rachel Clarke @drrachelclarke.com · 28/02/2025
This pair of absolute thugs berating, bullying & humiliating President Zelensky because he won’t roll over for a dictator whose forces have invaded his country, raped & murdered his people, bombed hospitals, killed children & filled mass graves in the forests. What a vile, venal pair they are.
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James O’Brien @mrjamesob.bsky.social · 28/02/2025
I think this is the closest many of us have ever got to seeing the real Trump. The only consistent thread in his entire unhinged rant was the love & praise for Vladimir Putin. Zelensky has more courage & dignity in his little finger than every member of Trump's regime & fan club combined.
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Fran Bottanelli @franbottanelli.bsky.social · 19/02/2025
Long in the making but our protocol for gene editing is online! FAB CRISPR is super easy and allows the generation of N and C terminal fusions with TurboID, SNAP, Halo and mStayGold. A single cloninf step to generate HDR templates! arxiv.org/abs/2502.12675 1/n
arxiv.org
Fast Antibiotic resistance-Based gene editing of mammalian cells with CRISPR-Cas9 (FAB-CRISPR)
Protein tagging with CRISPR-Cas9 enables the investigation of protein function in its native environment but is limited by low homology-directed repair (HDR) efficiency causing low knock-in rates. We ...
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