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Danny Saban

@sabanlab.bsky.social
1.1K followers 1.4K following 65 posts

Professor Immunologist leveraging the eye as an organ model system to study #neuroimmunology #mucosalimmunology #immuneprivilege #macrophages #microglia #DC #neutrophils youtube.com/@danielrsaban?si=4cOtXh…

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Reposted by Danny Saban
International Union of Immunological Societies @iuis-online.bsky.social · 30/09/2026
One week to go, and October 8 is World Sight Day. Five speakers on immunotherapy in eye disease: ocular surface disease, uveitis, AMD, and the eye-brain immune axis. Free to attend. Register: loom.ly/x1yU2EM #ImmunologyWithoutBorders #ImmunoHub #WorldSightDay
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Reposted by Danny Saban
ISER @iser.bsky.social · 26/08/2026
Claire Mitchell, Abe Clark, Dan Stamer, and Frank Lovicu after Dan Stamer's #ISER2026 Endre A. Balazs Prize lecture.
Claire Mitchell, Abe Clark, Dan Stamer, and Frank Lovicu on stage.
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Webvision @webvision.bsky.social · 20/08/2026
Niiiiice work from the Williams lab!
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 24/08/2026
Neutrophil remodeling is associated with human meibomian gland dysfunction and enables IFN-γ- and PAD4-dependent gland obstruction in mice www.biorxiv.org/content/10.64898/20…
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Danny Saban @sabanlab.bsky.social · 22/08/2026
Immunotherapy in eye disease: From immune pathobio... by Faculty / Presenters ; Oct 08 2026; immunohub.iuis.org/iuis/2026/we...
immunohub.iuis.org
Immunotherapy in eye disease: From immune pathobiology to... by Faculty / Presenters
; Presenters F. Oct 8 2026; 4230847;
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Danny Saban @sabanlab.bsky.social · 06/07/2026
ICYMI: The human cornea packs 7k nerve endings/mm², all from just a few hundred neurons. How that remarkable convergence is organized, and breaks down has long been difficult to resolve. Our NEI U01 consortium offers a tool-driven roadmap for what comes next iovs.arvojournals.org/article.aspx...
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Reposted by Danny Saban
Mariko Bennett @nachoriko.bsky.social · 24/03/2026
I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.
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Danny Saban @sabanlab.bsky.social · 24/03/2026
Resident tissue #macrophages (RTM) are now recognized as integral regulators of tissue physiology, not transient immune sentinels. one fundamental question remains unresolved: why do some populations achieve lifelong self-maintenance, while others are replaced under steady-state conditions? 🧵1/11
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Waggoner Lab @labwaggoner.bsky.social · 10/03/2026
Long-lived resident tissue macrophages govern intraocular pressure homeostasis by regulating extracellular matrix turnover, contributing to resistance-generating tissues that are dysfunctional in glaucoma @cp-immunity.bsky.social www.cell.com/immunity/ful... @dukeeyecenter.bsky.social
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Danny Saban @sabanlab.bsky.social · 22/01/2026
Preprint of National Eye Institute, U01-Funded Consortium Consensus on Ocular Surface Innervation is out ! "Corneal Innervation Research at a Crossroads: A Tool-Driven Roadmap for the Future "
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Danny Saban @sabanlab.bsky.social · 16/01/2026
#2016Nostalgia when we published our first #microglia paper ! www.nature.com/articles/sre...
nature.com
Fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina - Scientific Reports
Scientific Reports - Fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina
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Reposted by Danny Saban
Cheryl in Nova Scotia 🇨🇦🍁🍁 @minibubbly.bsky.social · 19/12/2025
Surfers in Bondi Beach #Australia hold a tribute the victims of the attack last week. ❤️
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Andres Hidalgo @drusqui.bsky.social · 12/12/2025
I am excited to share our new paper @JExpMed led by our one and only #Alejandra_Aroca
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Danny Saban @sabanlab.bsky.social · 27/11/2025
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Global Immunotalks @globalimmuno.bsky.social · 05/11/2025
Not to be missed! Our next #globalimmuno talk, today Wednesday, November 5th at 9am PST, noon EST, 5pm GMT by Dr. Daniel Saban. Title: “A Neuroimmune Niche that Underpins Touch Sensation” ZOOM LINK: us06web.zoom.us/webinar/regi... LIVE ON YOUTUBE: www.youtube.com/@GLOBALIMMUN...
us06web.zoom.us
Welcome! You are invited to join a webinar: GLOBAL IMMUNOTALKS: Virtual immunology seminar series . After registering, you will receive a confirmation email about joining the webinar.
Subscribe to our YouTube channel to stay updated and participate in the discussions: https://www.youtube.com/c/GLOBALIMMUNOTALKS We now offer: ✅ Live streaming on YouTube (in addition to Zoom) ✅ Asyn...
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Danny Saban @sabanlab.bsky.social · 29/09/2025
Welcome!
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Danny Saban @sabanlab.bsky.social · 07/09/2025
#CSNeuroimmune25 Come learn about a novel neuro immune niche that underpins touch! Littleton Tues P2.38 13:00-14:30 youtu.be/BAtzNKj4wxA?si…
youtu.be
Supplemental Video 2_Littleton et al_2025
YouTube video by Daniel R. Saban
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Kavitha Scranton @kavithascranton.bsky.social · 07/09/2025
Getting ready for #CSNeuroimmune25 tomorrow in NYC! Excited to see everyone, and looking forward to some cool #neuroimmunology! @cp-neuron.bsky.social @cp-immunity.bsky.social www.cell-symposia.com/neuroimmunol...
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Jeremy Berg @jeremymberg.bsky.social · 15/08/2025
Fierce Biotech story about the "priorities" memo www.fiercebiotech.com/research/nih... 1/4
fiercebiotech.com
NIH chief calls for immediate research review, dangling threat of project termination
Jayanta Bhattacharya, M.D., Ph.D., director of the National Institutes of Health (NIH), has called on the agency’s scientific leadership to immediately review all of their current and planned resea | ...
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Itai Yanai @itaiyanai.bsky.social · 14/08/2025
Some say you either have "it" or you don't, and that creativity cannot be learned, but that really misses the point. Creativity is lost in the wrong environment. We need to recognize the "night science" aspect of our work and that we need to nurture it in our training. www.nature.com/articles/d41...
nature.com
Can creativity in science be learnt? These researchers think so
Time pressure gets in the way of ideas. Developing ‘creative oases’ and small grants for risky ideas can encourage innovative thinking in science.
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Reposted by Danny Saban
Jeremy Berg @jeremymberg.bsky.social · 08/08/2025
New Notice about No-Cost Extensions... grants.nih.gov/grants/guide...
grants.nih.gov
NOT-OD-25-142: Update: No-Cost Extension Functionality in eRA
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Update: No-Cost Extension Functionality in eRA NOT-OD-25-142. NIH
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Danny Saban @sabanlab.bsky.social · 05/08/2025
Check out our new preprint on a novel neuro-immune niche that underpins touch in the cornea
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Leon Smyth @leonsmyth.bsky.social · 31/07/2025
Beautiful spatial transcriptomics of developing meninges and meningiomas. Hints into the origins of meningiomas arising from the dural border 🤩🧐
biorxiv.org
Cell atlas of the developing human meninges reveals a dura origin of meningioma
The vertebrate central nervous system is enveloped by the meninges, consisting of the pia, arachnoid, and dura layers. The arachnoid is hypothesised to give rise to the most common primary intracrania...
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Reposted by Danny Saban
@arvoinfo.bsky.social‬ @arvoinfo.bsky.social · 23/07/2025
You don’t see #VisionResearch. But it sees you. Most of us don’t think about vision research. But millions live every day with the impact of it—when it’s there, and when it’s not. Vision research changes lives. bit.ly/3GXVIaZ #SeeWhatMatters #FundFederalVisionResearch
Two persons cooking together in a kitchen, with text stating "15 million Americans are visually impaired" and hashtag "See What Matters."
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Reposted by Danny Saban
Waggoner Lab @labwaggoner.bsky.social · 22/04/2025
Previously unknown prenatally derived macrophage is uniquely involved in lipid metabolism and vascular maintenance and is decreased and dysfunctional in age-related macular degeneration @jem.org rupress.org/jem/article/...
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Reposted by Danny Saban
Journal of Experimental Medicine @jem.org · 20/06/2025
Fortmann, Grant et al. show that prenatally derived #macrophages support choroidal health and decline in age-related #maculardegeneration rupress.org/jem/article/... 📘 In our Clinical #Immunology Collection: rupress.org/jem/collecti... #FOCIS2025
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Lucie Van Emmenis @lucie-jexpmed.bsky.social · 08/07/2025
Wow.. this cover!! 😍 @jem.org looking jazzy this month! Take a look at the July issue here 👉 rupress.org/jem/issue/22...
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Jonathan Kipnis @jonykipnis.bsky.social · 24/07/2025
Excited to share our new work, led by an exceptional graduate student, Tornike Mamuladze, on the role of meningeal mast cells in regulation of brain/dura access points, with implications to CSF flow dynamics and meningitis || www.cell.com/cell/fulltex...
cell.com
Mast cells regulate the brain-dura interface and CSF dynamics
Dural mast cells control cerebrospinal fluid dynamics at critical brain-dura interfaces, specifically arachnoid cuff exit points. Their activation limits pathogen brain entry via histamine-induced vas...
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Reposted by Danny Saban
Neil deGrasse Tyson @neildegrassetyson.com · 19/05/2025
If a foreign adversary snuck into our Federal budget and cut science research and education the way we’re cutting it ourselves — strategically undermining America’s long-term health, wealth, and security — we would likely consider it an act of war.
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Danny Saban @sabanlab.bsky.social · 18/05/2025
Organoids don’t have immune systems
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Reposted by Danny Saban
Kavitha Scranton @kavithascranton.bsky.social · 13/05/2025
Excited to see this collection out! Thank you to all the authors and reviewers who contributed!
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Danny Saban @sabanlab.bsky.social · 07/05/2025
Assistant prof opening for Immunology umc.edu/som/Departme...
umc.edu
Employment Opportunities
The Department of Cell and Molecular Biology at the University of Mississippi Medical Center invites applications for a tenure-track faculty position at the rank of Assistant Professor. We seek an i...
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Reposted by Danny Saban
Kamal M Khanna @khannakm.bsky.social · 25/04/2025
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling: Immunity www.cell.com/immunity/ful... our study out now in@cp-immunity.bsky.social #macrophages
cell.com
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling
The local immunoregulatory mechanisms that safeguard the host from excessive lung infection inflammation remain unclear. Yeung, Yokota et al. uncover the essential role of nerve- and airway-associated...
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Reposted by Danny Saban
PHD Comics @phdcomics.com · 22/04/2025
Reimbursement
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Danny Saban @sabanlab.bsky.social · 10/04/2025
Sejiro Littleton takes home the coveted #GliaCamp best talk award 🥇. “Neuroimmune niche underpins touch.” He’s on the market for a postdoc position, for those who are asking! @MosemanLab @FilianoLab and students organized another wonderful camp ⛺️. @LongJun_Wu killer keynote@ - who can ask for more
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Nature Reviews Immunology @natrevimmunol.nature.com · 03/04/2025
More great content from @preprintclub.bsky.social @epelmanlab.bsky.social. This @biorxiv-immuno.bsky.social preprint from Liu et al. reports that resident tissue macrophages in the conventional outflow tract regulate intraocular pressure.
nature.com
Resident tissue macrophages maintain intraocular pressure by regulating extracellular matrix homeostasis - Nature Reviews Immunology
A preprint by Liu et al. shows that resident tissue macrophages in the conventional outflow tract regulate intraocular pressure in the steady state.
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Danny Saban @sabanlab.bsky.social · 01/04/2025
Thank you @natrevimmunol.bsky.social and Preprint Club, University of Toronto, Alex Lac & ⁦‪Slava Epelman‬⁩ for reviewing our preprint! www.nature.com/articles/s41...
nature.com
Resident tissue macrophages maintain intraocular pressure by regulating extracellular matrix homeostasis - Nature Reviews Immunology
A preprint by Liu et al. shows that resident tissue macrophages in the conventional outflow tract regulate intraocular pressure in the steady state.
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Danny Saban @sabanlab.bsky.social · 14/03/2025
National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Res…
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Eric Topol @erictopol.bsky.social · 10/03/2025
99% of new medicines developed by the pharmaceutical industry depend on NIH research jamanetwork.com/journals/jam...
jamanetwork.com
Comparison of Research Spending on New Drug Approvals by the NIH vs the Pharmaceutical Industry
This cross-sectional study examines National Institutes of Health and pharmaceutical industry investments in recent drug approvals.
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Jeremy Berg @jeremymberg.bsky.social · 03/03/2025
Another Orwellial this morning But with some good news...
media.tenor.com
a cartoon of homer simpson holding a card
ALT: a cartoon of homer simpson holding a card
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 28/01/2025
Resident Tissue Macrophages Govern Intraocular Pressure Homeostasis www.biorxiv.org/content/10.1101/202…
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Danny Saban @sabanlab.bsky.social · 27/01/2025
clip.cafe/halloween-20...
clip.cafe
'I'm a doctor. Lock your doors.' - Halloween
Dr. Sartain: I'm a doctor. Lock your doors.
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Reposted by Danny Saban
Journal of Experimental Medicine @jem.org · 23/01/2025
Our new #immunology collection highlights recent studies on barrier immunity, microbiota, molecular immunology, neuroimmunology, and stem cells and regeneration. Explore new research from JEM to accompany the @midwinter-immun.bsky.social Conference! 📚👉 buff.ly/4geAP6W
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Itai Yanai @itaiyanai.bsky.social · 16/12/2024
🔥Today's new episode of the Night Science Podcast is super cool: A hypothesis is a liability! We talk about the interplay between hypothesis-driven and exploratory research, and discuss the insights of previous guests of the podcast. I'm really curious to know what you'll think!
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Danny Saban @sabanlab.bsky.social · 12/12/2024
Haha!
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Shane Liddelow @liddelowsa.bsky.social · 11/12/2024
3 reviews on planning, execution, & validation of transcriptomic experiments in neuroscience published in @natureportfolio.bsky.social #NatureNeuroscience. A MUST READ if you're doing transcriptomics. 3 reviews, an amazing editorial, a beautiful cover – this is the issue of the year! (mini thread)
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Jaime Grutzendler @jgrutzendler.bsky.social · 10/12/2024
likewise, happy to have contributed to the comprehensive update on this important topic
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BWJones @bwjones.bsky.social · 09/12/2024
Lots of things should scale with GDP. In 1963, we spend 2.5% of GDP on science and research in America. In 2024, we are spending 0.5% GPD on science and research in America.
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Shari Wiseman @shariwiseman.bsky.social · 09/12/2024
Nature Neuroscience is hiring a computational/systems/cognitive editor! Come join our team! Happy to answer any questions. springernature.wd3.myworkdayjobs.com/SpringerNatu...
springernature.wd3.myworkdayjobs.com
Associate or Senior Editor, Nature Neuroscience
Job Title: Associate or Senior Editor, Nature Neuroscience Location: New York, Jersey City, Philadelphia, Washington D.C., Berlin or Shanghai Application Deadline: January 6, 2025 About Springer Natur...
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Danny Saban @sabanlab.bsky.social · 08/12/2024
Looking forward to seeing how CAFE projected our spectral flow dataset from 2021, "Mucosal-associated invariant T cell responses differ by sex in COVID-19: Med www.cell.com/med/fulltext... www.biorxiv.org/content/10.1...
biorxiv.org
CAFE: An Integrated Web App for High-Dimensional Analysis and Visualization in Spectral Flow Cytometry
Spectral flow cytometry provides greater insights into cellular heterogeneity by simultaneous measurement of up to 50 markers. However, analyzing such high-dimensional (HD) data is complex through tra...
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