Human aging is a heterogeneous, multi-system process that spans molecular, tissue, and physiological decline. In this issue of Cell, Li et al. integrate clinical data, multi-omics, and organ-associate...

Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the n...

Gallrein et al. pair functional assays with clocks to compare chronological versus biological age of single neuron types in C. elegans, to probe their vulnerability or resilience to neurodegeneration,...

Cyril Alias erklärt, wie ein Autopilot Binnenschiffe durch Flussbiegungen und Stromschnellen navigieren könnte.

Alternsforscher Björn Schumacher über ewiges Leben, unseriöse Versprechen und Faktoren, die das Leben wirklich verlängern können.

Ein Gespräch mit dem Biologen Björn Schumacher über die Geheimnisse von Longevity – einem möglichst langen, gesunden Leben.

YouTube video by detektor.fm

The dauer diapause is a naturally occurring extraordinarily long-lived alternative C. elegans larval stage that, upon dauer exit, lives a normal adult life with full reproductive capacity. Here, we d...

The faithful transmission of genomic DNA over succeeding generations is an essential prerequisite for species maintenance. The germplasm theory by August Weismann has been foundational for the current...

Researchers from the University of Cologne discovered how a specific dietary amino acid increases cellular energy, opening new possibilities for treating metabolic diseases / publication in “Nature Ce...

ALT: a computer generated image of a dna molecule with a dark background

YouTube video by CECAD Cologne

Meyer and colleagues refute the idea that, as aging can be tracked precisely by clocks, it must be driven by a biological program. They propose that imperfect maintenance and repair processes resultin...

YouTube video by CECAD Cologne

We are looking to support our rapidly growing team as soon as possible:

A new DFG-funded research group investigates how proteostasis is regulated at the organismal level and its impact on aging and disease.