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Reposted by @sedakoyuncu.bsky.social

Nature Aging @nataging.nature.com · 04/09/2025

Online now! @thevilchezlab.bsky.social @sedakoyuncu.bsky.social identify age-related hyperactivation of EPS8/RAC signaling in C.elegans as a driver of pathological protein aggregation, highlighting EPS8 and its regulators as potential therapeutic targets. www.nature.com/articles/s43...

nature.com

The aging factor EPS8 induces disease-related protein aggregation through RAC signaling hyperactivation - Nature Aging

Aging is a risk factor for neurodegenerative diseases associated with protein aggregation. Here the authors identify age-related hyperactivation of EPS8/RAC signaling in C. elegans as a driver of path...

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